“…The 14-3-3 proteins are a family of ubiquitous and exclusively eukaryotic proteins with an astoundingly significant number of binding partners. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A series of 3(2)-phosphonylated thiazolo[3,2-a]oxopyrimidines was synthesized for the first time by the reactions of chloroethynylphosphonates with unsubstituted and 5(6)-substituted 2-thiouracils. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Exostosin-like 3 (EXTL3) encodes the glycosyltransferases responsible for the biosynthesis of the backbone structure of heparan sulfate (HS), a sulfated polysaccharide that is ubiquitously distributed on the animal cell surface and in the extracellular matrix. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In an analysis of these datasets it was observed that a single dataset does not have the types of infrared images, visible and three-dimensional light, for the same sample. Given this context, the present work conceived this 3D facial dataset, with its respective visible light image and infrared spectrum, providing the entire image acquisition process from the Kinect One device. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Vimentin, an intermediate filament protein present in leukocytes, blood vessel endothelial cells, and multiple mesenchymal cells, such as mouse embryonic fibroblasts (MEF 3T3), is crucial for various cellular processes, as well as for maintaining the integrity and durability (stability) of the cell cytoskeleton. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, the functions of many kinases are regulated through protein–protein interactions, which in turn are mediated by phosphorylated motifs and often involve associations with the scaffolding and chaperon protein 14-3-3. Therefore, the aim of this review article is to provide an overview of the state of the art on 14-3-3-mediated kinase regulation, focusing on the most recent mechanistic insights into these important protein–protein interactions and discussing in detail both their structural aspects and functional consequences.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MATERIALS AND METHODS: 3T3-L1 preadipocytes were incubated with differentiation induction medium in the presence or absence of 0.5, 2.5, or 5 µM juglanin for an 8-day differentiation period. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nanoparticles of pure α-La(IO(3))(3) and pure δ-La(IO(3))(3) were synthesised via the new method depending on the source of iodate ions, thereby demonstrating the versatility of the synthesis route. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The cell viability of podocytes decreased after lyso-Gb3 treatment in a dose-dependent manner, with increasing RIPK3 expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The seven 14-3-3 isoforms are highly abundant human proteins encoded by similar yet distinct genes. 14-3-3 proteins recognize phosphorylated motifs within numerous human and viral proteins. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patients with schizophrenia exhibit irregular neuronal circuit and network activity, but the causes and consequences of such activity remain largely unknown. Inhibition of 14-3-3 proteins in the mouse brain leads to the expression of multiple schizophrenia endophenotypes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The title compound, tri­carbonyl­tris­(dimethyl sulfoxide)­molybdenum, [Mo(C(2)H(6)OS)(3)(CO)(3)] or fac-[Mo(CO)(3)(DMSO)(3)], crystallizes in the triclinic space group P [Image: see text] with two mol­ecules in the unit cell. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…3H-1,2-Dithiole-3-thiones are among the best studied classes of polysulfur-containing heterocycles due to the almost explosive recent interest in these compounds as sources of hydrogen sulfide as an endogenously produced gaseous signaling molecule. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…TE generally requires parenteral nutrition (PN) during childhood or intestinal bowel transplantation. We report three unrelated families with six children with TE. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Structural comparison with dinuclear thiocyanate‐bridged (PN)(2)La(μ‐1,3‐SCN)(2)La(PN)(2) (3) and azide‐bridged (PN)(2)La(μ‐1,3‐N(3))(2)La(PN)(2) (4) complexes indicates that the [SCP](−) coordination mode is mainly governed by electronic, rather than steric factors. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…One primary reason for this could be that IP(3)R2 has been used to represent all astrocytic IP(3)Rs, including IP(3)R1 and IP(3)R3. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…[Image: see text] Titanium(III) is a useful strong reductant and is usually standardized with iron(III) in volumetric analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We report a new class of antileishmanial leads, the 3-arylquinolines, that potently block proliferation of the intramacrophage amastigote form of Leishmania parasites with good selectivity relative to the host macrophages. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso