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1761“…We analyzed the synaptic density, 3D spatial distribution, and type (asymmetric/symmetric), as well as the size and shape of each synaptic junction of 4945 synapses that were fully reconstructed in 3D. …”
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1762“…We then briefly describe the implication of 14-3-3s in the central nervous system and focus on their interaction with LRRK2, α-Synuclein, and Parkin, three of the major players in PD onset and progression. …”
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1763“…It was found that 4-hydroxy-2-butenoic ester (11) could not react with 3,4-dihydro-isoquinoline (4a). Individual addition reactions of γ-mercapto-α,β-unsaturated esters (18) and -unsaturated amide (19) with 3,4-dihydroisoquinolines (4) were carried out under appropriate conditions to provide the corresponding thiazolo[2,3-α]isoquinoline derivatives with good yields (up to 87%) and significant diastereomeric selectivity. …”
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1764por Venkataramanan, Srivats, Gadek, Margaret, Calviello, Lorenzo, Wilkins, Kevin, Floor, Stephen N.“…DDX3 is a DEAD-box RNA helicase that regulates translation and is encoded by the X- and Y-linked paralogs DDX3X and DDX3Y. …”
Publicado 2021
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1765por Sakurai, Takuma, Horigome, Ayako, Odamaki, Toshitaka, Shimizu, Takashi, Xiao, Jin-Zhong“…Hydroxycarboxylic acid receptor 3 (HCA(3)) was recently identified in the genomes of humans and other hominids but not in other mammals. …”
Publicado 2021
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1766“…More importantly, this review put more efforts to illustrate how the 3D biomaterial systems affect to modulate antitumor immune activities, where we discussed how significant the roles and behaviours of 3D macroscale scaffolds towards in situ cancer immunotherapy in order to direct the design of 3D immunotherapeutic.…”
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1767por Mersaoui, Sofiane Y., Guilbert, Cynthia, Chou, Hsiang, Douillet, Christelle, Bohle, D. Scott, Stýblo, Miroslav, Richard, Stéphane, Mann, Koren K.“…In human and mouse, inorganic arsenic (iAs) is metabolized in a series of methylation steps catalyzed by arsenic (3) methyltransferase (AS3MT), forming methylated arsenite (MAsIII), dimethylarsenite (DMAIII) and the volatile trimethylarsine (TMA). …”
Publicado 2022
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1768por He, Lingli, Yu, Zhuoya, Geng, Ze, Huang, Zhuo, Zhang, Changjiang, Dong, Yanli, Gao, Yiwei, Wang, Yuhang, Chen, Qihao, Sun, Le, Ma, Xinyue, Huang, Bo, Wang, Xiaoqun, Zhao, Yan“…Ca(V)3.3 contains a long bended S6 helix from domain III, with a positive charged region protruding into the cytosol, which is critical for T-type Ca(V) channel activation at low voltage. …”
Publicado 2022
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1769“…Herein, we report a ring-opening 1,3-arylboration of aryl cyclopropanes using BCl(3) in the presence of arene nucleophiles. …”
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1770“…Cutis Vertcis gyrata is an uncommon neurocutaneous syndrome characterized by excessive growth of the skin of the scalp or the face, forming folds of similar aspect to cerebral cortex gyri. Three categories have been individualized: the primary form, essential or non‐essential, and the secondary form.…”
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1771“…The above findings illustrate that the proposed three-phase 3D electrochemical process is feasible for the efficient treatment of greywater.…”
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1772por Fratilescu, Ion, Lascu, Anca, Taranu, Bogdan Ovidiu, Epuran, Camelia, Birdeanu, Mihaela, Macsim, Ana-Maria, Tanasa, Eugenia, Vasile, Eugeniu, Fagadar-Cosma, Eugenia“…Porphyrins are versatile structures capable of acting in multiple ways. A mixed substituted A(3)B porphyrin, 5-(3-hydroxy-phenyl)-10,15,20-tris-(3-methoxy-phenyl)-porphyrin and its Pt(II) complex, were synthesised and fully characterised by (1)H- and (13)C-NMR, TLC, UV-Vis, FT-IR, fluorescence, AFM, TEM and SEM with EDX microscopy, both in organic solvents and in acidic mediums. …”
Publicado 2022
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1773por Jehan, Frédéric, Zarka, Mylène, de la Houssaye, Guillaume, Veziers, Joëlle, Ostertag, Agnès, Cohen‐Solal, Martine, Geoffroy, Valérie“…We investigate the role of Matrix Metalloproteinase 3 (MMP3) on bone in mice, by using Mmp3 knockout (Mmp3 KO) in the context of estrogen deficiency, and in human, by analyzing the association of promoter polymorphism with bone mineral density in postmenopausal women and with MMP3 expression. …”
Publicado 2022
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1774por Zhao, Yongheng, Fang, Guangchi, Guo, Yulan, Guibas, Leonidas, Tombari, Federico, Birdal, Tolga“…We present 3DPointCaps++ for learning robust, flexible and generalizable 3D object representations without requiring heavy annotation efforts or supervision. …”
Publicado 2022
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1775por Perry-Hauser, Nicole A., Kaoud, Tamer S., Stoy, Henriette, Zhan, Xuanzhi, Chen, Qiuyan, Dalby, Kevin N., Iverson, Tina M., Gurevich, Vsevolod V., Gurevich, Eugenia V.“…We identified a 16-residue arrestin-3-derived peptide expressed as a Venus fusion that leads to activation of JNK3α2 in cells. …”
Publicado 2022
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1776“…Fusion of the fibroblast growth receptor 3 and the transforming acidic coiled coil containing protein—FGFR3-TACC3 fusion—is prevalent in 3–4% of human glioblastoma. …”
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1777por Parvizian, Mahsa, Duràn Balsa, Alejandra, Pokratath, Rohan, Kalha, Curran, Lee, Seungho, Van den Eynden, Dietger, Ibáñez, Maria, Regoutz, Anna, De Roo, Jonathan“…The precursor conversion chemistry and surface chemistry of Cu(3)N and Cu(3)PdN nanocrystals are unknown or contested. …”
Publicado 2022
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1778
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1779“…This article reviews the evidence behind a novel biomarker 14-3-3 η that has been found to provide additional diagnostic and prognostic information as well as predicting response to treatment. …”
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1780por Kodan, Lachmi R., Verschueren, Kim J.C., Paidin, Raez, Paidin, Rubinah, Browne, Joyce L., Bloemenkamp, Kitty W.M., Rijken, Marcus J.“…Obstetrical hemorrhage was less often the underlying cause of death over the years (19 of 64 [30%], vs 13 of 65 [20%], vs 7 of 62 [11%]), whereas all other obstetrical causes occurred more often in confidential enquiry into maternal deaths III (eg, suicide [0; 1 of 65 (2%); 5 of 62 (8%)]) and unspecified deaths (1 of 64 [2%]; 3 of 65 [5%]; and 11 of 62 [18%] in confidential enquiry into maternal deaths I, II and III respectively). …”
Publicado 2021
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