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  1. 2441
    “…Cytotoxic T lymphocytes are effector CD8(+) T cells that eradicate infected and malignant cells. …”
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    NFATc1 controls the cytotoxicity of CD8(+) T cells
  2. 2442
    “…A large population of CD8(+) T cells is in direct and constant contact with the IECs and the intraepithelial lymphocytes (IELs). …”
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    Intestinal Barrier Interactions with Specialized CD8 T Cells
  3. 2443
    “…Among a plethora of soluble factors, IL-8 has been considered one of the most relevant to support CLL B cell progression in an autocrine fashion, even though the expression of IL-8 receptors, CXCR1 and CXCR2, on leukemic B cells has not been reported. …”
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    Revisiting the role of interleukin-8 in chronic lymphocytic leukemia
  4. 2444
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    Structural basis of human kinesin-8 function and inhibition
  5. 2445
    “…TRPM8 is a Ca(2+)-permeable nonselective cation channel belonging to the melastatin sub-group of the transient receptor potential (TRP) family. …”
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    TRPM8 is required for survival and radioresistance of glioblastoma cells
  6. 2446
    “…BACKGROUND: Histone deacetylase 8 from Schistosoma mansoni (SmHDAC8) is essential to parasite growth and development within the mammalian host and is under investigation as a target for the development of selective inhibitors as novel schistosomicidal drugs. …”
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    Analysis of the interactome of Schistosoma mansoni histone deacetylase 8
  7. 2447
    por Schmidt, Megan E., Varga, Steven M.
    Publicado 2018
    “…In addition, memory CD8 T cells are capable of providing protection against secondary infections. …”
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    The CD8 T Cell Response to Respiratory Virus Infections
  8. 2448
    “…Hoxb8 mutant mice exhibit compulsive grooming and hair removal dysfunction similar to humans with the OCD-spectrum disorder, trichotillomania. …”
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    Corticostriatal circuit defects in Hoxb8 mutant mice
  9. 2449
    “…Gene editing of mouse Mxra8 or human MXRA8 resulted in reduced viral infection of cells, and reciprocally, ectopic expression resulted in increased infection. …”
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    Mxra8 is a receptor for multiple arthritogenic alphaviruses
  10. 2450
    “…Mutations of the gene MEGF8 cause Carpenter syndrome in humans, and the mouse orthologue has been functionally associated with Nodal and Bmp4 signalling. …”
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    The Drosophila homologue of MEGF8 is essential for early development
  11. 2451
    “…Zinc finger DHHC-type containing 8 (ZDHHC8) is a putative palmitoyltransferase that is highly expressed in the brain. …”
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    ZDHHC8 critically regulates seizure susceptibility in epilepsy
  12. 2452
    por Chan, Carmen
    Publicado 2018
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    Highlights – 8(th) Nursing Symposium on Cancer Care
  13. 2453
    “…Persistent infection or chronic inflammation contributes significantly to tumourigenesis and tumour progression. C-X-C motif ligand 8 (CXCL8) is a chemokine that acts as an important multifunctional cytokine to modulate tumour proliferation, invasion and migration in an autocrine or paracrine manner. …”
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    The CXCL8-CXCR1/2 pathways in cancer
  14. 2454
    “…Additionally, several functional 2,8-ethanonoradamantane derivatives have been prepared.…”
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    Alternative Access to Functionalized 2,8-Ethanonoradamantane Derivatives
  15. 2455
    “…We also discuss some unresolved problems, such as how CD8(+) Trm cells adapt to the local tissue microenvironment, how Trm cells interact with other immune cells during their development and maintenance, and the mechanisms by which CD8(+) Trm cells confer immune protection. …”
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    CD8(+) Resident Memory T Cells and Viral Infection
  16. 2456
    “…The 8-hydroxyquinoline pharmacophore scaffold has been shown to possess a range of activities as metal chelation, enzyme inhibition, cytotoxicity, and cytoprotection. …”
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    Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products
  17. 2457
    “…A general scheme for the synthesis of C8-arylpurine phosphoramidites has been developed. …”
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    A General Synthesis of C8-Arylpurine Phosphoramidites
  18. 2458
    “…In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. …”
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    Investigating the Activity Spectrum for Ring-Substituted 8-Hydroxyquinolines
  19. 2459
    “…8-Gingerol is one of the principal components of ginger, which is widely used in China and elsewhere as a food, spice and herb. …”
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    Immunosuppressive Activity of 8-Gingerol on Immune Responses in Mice
  20. 2460
    “…Condensation of 3-acetyl-8-ethoxycoumarin (3) with thiosemicarbazide gave ethylidenehydrazinecarbothioamide 5, which was transformed into the thiazolidin-4-one derivatives 6,7. …”
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    Synthesis, Reactions and Antimicrobial Activities of 8-Ethoxycoumarin Derivatives
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