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  1. 2461
    “…Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare primary human immunodeficiency characterized by recurrent cutaneous and systemic infections, as well as atopy and cancer susceptibility(5). …”
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    Expanded skin virome in DOCK8-deficient patients
  2. 2462
    “…To investigate the role of E2F8 in human placental development, E2F8 localisation was examined in the human placenta and E2F8 mRNA expression was detected in primary cultured EVTs. …”
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    The role of E2F8 in the human placenta
  3. 2463
    “…Our research aimed at clarifying the antifungal mechanism of action of clioquinol, 8-hydroxy-5-quinolinesulfonic acid, and 8-hydroxy-7-iodo-5-quinolinesulfonic acid (three 8-hydroxyquinoline derivatives). …”
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    New insights into the mechanism of antifungal action of 8-hydroxyquinolines
  4. 2464
    por Edzuka, Tomoya, Goshima, Gohta
    Publicado 2019
    “…Kinesin-8 is required for proper chromosome alignment in a variety of animal and yeast cell types. …”
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    Drosophila kinesin-8 stabilizes the kinetochore–microtubule interaction
  5. 2465
    “…A number of cadherins were found to be expressed differentially, with Cadherin-8 (Cdh8) selectively present in the IZ stream. …”
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    Cadherin 8 regulates proliferation of cortical interneuron progenitors
  6. 2466
    “…The authors report a rare case of cystic lymphangioma in the right elbow of an 8-month-old baby treated successfully by complete surgical resection.…”
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    Elbow Cystic Lymphangioma in an 8-Month-Old Boy
  7. 2467
    por Straiton, Jennifer
    Publicado 2019
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    Welcome to Volume 8 of the International Journal of Hematologic Oncology
  8. 2468
    “…A common ZnT8 gene (SLC30A8) polymorphism increases the risk of type 2 diabetes mellitus (T2DM), and rare mutations may present protective effects. …”
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    Genetic, Functional, and Immunological Study of ZnT8 in Diabetes
  9. 2469
    por Cheyuo, Cletus, Aziz, Monowar, Wang, Ping
    Publicado 2019
    “…We propose further investigation of the molecular pathways for MFG-E8 signaling in NSPC and effective strategies for MFG-E8 delivery across the blood–brain barrier, which will help develop MFG-E8 as a future drug candidate for the bedside management of neurodegenerative diseases.…”
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    Neurogenesis in Neurodegenerative Diseases: Role of MFG-E8
  10. 2470
    “…With the rapid development of experimental and computational methods, it is of great interest to integrate these approaches to illuminate the conformational landscapes of target proteins. SETD8 is a protein lysine methyltransferase (PKMT), which functions in vivo via the methylation of histone and nonhistone targets. …”
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    The dynamic conformational landscape of the protein methyltransferase SETD8
  11. 2471
    “…CD8 T cells are infrequently considered part of germinal center reactions. …”
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    CXCR5+ CD8 T Cells: Protective or Pathogenic?
  12. 2472
    “…In addition, we focus on whether the differentiation state of CMV-specific CD8 T cells is unique in comparison with other chronic viruses and we will discuss the possible impact of factors such as antigen exposure and aging on the advanced differentiation status of CMV-specific CD8 T cells.…”
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    The hallmarks of CMV-specific CD8 T-cell differentiation
  13. 2473
    por Hassan, Neelam, Lorenzi, Alice
    Publicado 2017
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    8. A diagnostic and management dilemma of coexisting arthropathies
  14. 2474
    “…DiGeorge syndrome critical region 8 (DGCR8) is a critical component of the canonical microprocessor complex for microRNA biogenesis. …”
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    Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis
  15. 2475
    “…In this paper, the potential existence of two-gap superconductivity in Mo(8)Ga(41) is addressed in detail by means of thermodynamic and spectroscopic measurements. …”
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    Single-gap superconductivity in Mo(8)Ga(41)
  16. 2476
    por Liu, Xia, Li, Lingyun, Peng, Guangyong
    Publicado 2019
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    TLR8 reprograms human Treg metabolism and function
  17. 2477
    “…Of the four bases, guanine is the most susceptible to oxidation, which results in the formation of 8-oxoguanine (8-oxoG). In protein-free DNA, 8-oxodG adopts the syn conformation more frequently than the anti one. …”
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    Insights into the base-pairing preferences of 8-oxoguanosine on the ribosome
  18. 2478
    por Lystad, Alf Håkon, Simonsen, Anne
    Publicado 2019
    “…Importantly, comprehensive structural and biochemical in vitro studies of the machinery required for ATG8 protein lipidation, as well as their genetic manipulation in various model organisms, have provided novel insight into the molecular mechanisms and pathophysiological roles of the mATG8 proteins. …”
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    Mechanisms and Pathophysiological Roles of the ATG8 Conjugation Machinery
  19. 2479
    “…We applied systematic review guidelines to study MMP8 in cancer including the use of MMP8 as a prognostic factor or as a target/anti-target in cancer treatment, and its molecular mechanisms. …”
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    The Role of MMP8 in Cancer: A Systematic Review
  20. 2480
    “…Our results indicate that Atg8’s invagination-suppressing functions do not require Atg8 lipidation, in contrast with autophagy, which requires Atg8 lipidation. …”
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    Role of Atg8 in the regulation of vacuolar membrane invagination
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