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  1. 2721
    “…In view of the increasing demand for constitutionally and stereochemically defined CP standards, we have synthesized a stereoisomeric mixture of 3,4,7,8-tetrachlorodecane. One stereoisomer – (3R,4R,7S,8S)-3,4,7,8-tetrachlorodecane was separated from the mixture, and enriched fractions of residual stereoisomers were achieved through crystallisation of the residual mother liquors. …”
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    Synthesis, identification, chiral separation and crystal structure of (3R,4R,7S,8S)-3,4,7,8-tetrachlorodecane and its stereoisomers
  2. 2722
    “…The detection rates of RVAs were 19.40% (142/732) and 3.51% (8/228) in children and adults, respectively. G9P[8] was the predominant genotype, followed by G8P[8] and G3P[8]. …”
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    Surveillance of Human Rotaviruses in Wuhan, China (2019–2022): Whole-Genome Analysis of Emerging DS-1-like G8P[8] Rotavirus
  3. 2723
    “…Most T cells belong to either of two lineages defined by the mutually exclusive expression of CD4 and CD8 coreceptors: CD4 T cells are major histocompatibility complex (MHC) II restricted and have helper function, whereas CD8 T cells are MHC I restricted and have cytotoxic function. …”
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    Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation
  4. 2724
    “…The type 2 diabetes nonsynonymous single nucleotide polymorphism (SNP) affecting aa(325) lies within the region of highest ZnT8 autoantibody (ZnT8A) binding, prompting an investigation of its relationship to type 1 diabetes. …”
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    A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes
  5. 2725
    “…CT inhibited the function of interferon (IFN) regulatory factor (IRF) 8, a transcription factor known to positively regulate IL-12p35 and p40 gene expression, and the differentiation of CD8α(+) and plasmacytoid DCs (pDCs). …”
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    Cholera toxin inhibits IL-12 production and CD8α(+) dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function
  6. 2726
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    Cholera toxin inhibits IL-12 production and CD8α(+) dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function
  7. 2727
    “…Together, our data bring forth the possibility that, in addition to the FGF synexpression group, autoregulation of FGFR expression by FGF8 represents a mechanism by which FGF8 could fine-tune its regulatory actions.…”
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    Differential Fibroblast Growth Factor 8 (FGF8)-Mediated Autoregulation of Its Cognate Receptors, Fgfr1 and Fgfr3, in Neuronal Cell Lines
  8. 2728
    por Liu, Guang-Xiang
    Publicado 2010
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    4,4′-Dimethyl-1,1′-(p-phenyl­enedimethyl­ene)dipyridinium bis­[7,7,8,8-tetra­cyano­quinodimethanide(1−)]
  9. 2729
    por Jian, Fangfang, Zhai, Xin
    Publicado 2010
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    8-(4-Chloro­benzyl­idene)-4-(4-chloro­phen­yl)-2-phenyl-5,6,7,8-tetra­hydro­quinoline
  10. 2730
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    (R)-2′-Benz­yloxy-5,5′,6,6′,7,7′,8,8′-octa­hydro-1,1′-binaphthyl-2-ol
  11. 2731
    “…The title compound, [ZnBr(C(9)H(6)NO)(C(9)H(7)NO)]·CH(3)OH, has its metal atom N,O-chelated by a neutral and a deproton­ated 8-hy­droxy­quinoline ligand. The hy­droxy unit of the neutral ligand is a hydrogen-bond donor to the methanol O atom and the alk­oxy O atom of the monoanionic ligand is a hydrogen-bond acceptor to the methanol O atom. …”
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    Bromido(quinolin-8-ol-κ(2) N,O)(quinolin-8-olato-κ(2) N,O)zinc(II) methanol monosolvate
  12. 2732
    “…In the title solvated salt, (C(10)H(10)NO)[SnCl(4)(C(9)H(6)NO)]·CH(3)CN, the Sn(IV) atom is chelated by the N,O-bidentate 8-hydroxy­quinolinate ligand and four chloride ions, generating a distorted SnONCl(4) octa­hedral coordination geometry for the metal. …”
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    8-Hydr­oxy-2-methyl­quinolinium tetra­chlorido(quinolin-8-olato-κ(2) N,O)stannate(IV) acetonitrile monosolvate
  13. 2733
    “…No copy number variations (CNVs) disrupting CDH8 were observed in 5023 controls. Expression analysis indicates that the two CDH8 isoforms are present in the developing human cortex. …”
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    Rare familial 16q21 microdeletions under a linkage peak implicate cadherin 8 (CDH8) in susceptibility to autism and learning disability
  14. 2734
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    1,3-Dimethyl-5,6,7,8-tetra­hydro-4H-cyclo­hepta­[c]thio­phene-4,8-dione
  15. 2735
    “…Interestingly, compared to healthy controls, higher percentages of caspase-3 and caspase-8 positive CD4+ and CD8+ T-cells were demonstrated in HCV-infected patients at baseline. …”
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    Low doses of the novel caspase-inhibitor GS-9450 leads to lower caspase-3 and -8 expression on peripheral CD4+ and CD8+ T-cells
  16. 2736
    “…In the title compound, [Zn(C(9)H(6)NO)Cl(C(9)H(7)NO)]·CH(3)OH, the Zn(II) ion is N,O-chelated by both a neutral and a deprotonated quinolin-8-ol ligand, with a chloride ligand in the apical site completing the square-pyramidal coordination geometry. …”
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    Chlorido(8-hy­droxy­quinoline-κ(2) N,O)(quinolin-8-olato-κ(2) N,O)zinc methanol monosolvate
  17. 2737
    “…The reaction of 2-methyl-8-hy­droxy­quinoline and zinc chloride in acetonitrile affords the title solvated salt, (C(10)H(10)NO)[Zn(C(10)H(8)NO)Cl(2)]·2CH(3)CN, in which the Zn(II) atom is coordinated by an­ N,O-chelating 2-methyl­quinolin-8-olate ligand and two chloride ligands in a distorted tetra­hedral geometry. …”
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    8-Hy­droxy-2-methyl­quinolinium dichlorido(2-methyl­quinolin-8-olato-κ(2) N,O)zincate acetonitrile disolvate
  18. 2738
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    (1R*,5S*)-8-(2-Fluoro-4-nitro­phen­yl)-8-aza­bicyclo­[3.2.1]octan-3-one
  19. 2739
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    1-Hexyl-1,3,6,8-tetra­aza­tricyclo­[4.3.1.1(3,8)]undecan-1-ium iodide
  20. 2740
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    Time course of granulocyte–macrophage colony-stimulating factor and IL-8 in severe sepsis: are the initial low levels of IL-8 a consequence of immunodepression?
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