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3301Publicado 1991“…These results demonstrate for the first time binding of a class Ib molecule to CD8 with a functional outcome, as is observed for the class I transplantation antigens. …”
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3302por Stupack, Dwayne G., Puente, Xose S., Boutsaboualoy, Souphaphone, Storgard, Chris M., Cheresh, David A.“…Surprisingly, unligated integrin or β integrin tails recruit caspase-8 to the membrane, where it becomes activated in a death receptor–independent manner. …”
Publicado 2001
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3303por Nakamichi, Ikuo, Toivola, Diana M., Strnad, Pavel, Michie, Sara A., Oshima, Robert G., Baribault, Hélène, Omary, M. Bishr“…Keratins 8 and 18 (K8/18) are major constituents of Mallory bodies (MBs), which are hepatocyte cytoplasmic inclusions seen in several liver diseases. …”
Publicado 2005
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3304por Yang, Dongren, Bierman, Jesse, Tarumi, Yukie S., Zhong, Yong-Ping, Rangwala, Reshma, Proctor, Thomas M., Miyagoe-Suzuki, Yuko, Takeda, Shin'ichi, Miner, Jeffrey H., Sherman, Larry S., Gold, Bruce G., Patton, Bruce L.“…Combined Ln-2/Ln-8 deficiency caused nearly complete amyelination, revealing Ln-2 and -8 together have a dominant role in defasciculation, and that Ln-8 promotes myelination without BLs. …”
Publicado 2005
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3305Publicado 1990“…Contrary to existing dogma, evidence is presented that proliferative responses of mature unprimed T cells to Mlsa antigens involve CD8+ cells as well as CD4+ cells. The response of CD8+ cells to Mlsa antigens proved to be heavily dependent on help from CD4+ cells, and responses were stronger in three I-E+ strain combinations than in an I- E- combination. …”
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3306Publicado 1986“…We have presented a method for the extraction and isolation of the gonococcal H.8 antigen. There was no evidence of contamination by other gonococcal proteins, phospholipids, or LPS. …”
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3307Publicado 1987“…Recent experiments (11-13) have shown that antigen-specific, CD8+, CD4- T lymphocytes can be induced to proliferate and become killer cells in the absence of a second population of "helper" CD8-, CD4+ cells. …”
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3308Publicado 1987“…In general, the human CD8 molecule is expressed on T cells specific for HLA class I molecules. …”
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3309
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3310
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3311Publicado 1996“…Also, the expansion of CD8+ T cells was not affected by the absence of B cells and/or antibody; in both groups of mice there was an approximately 10,000-fold increase in the number of LCMV-specific CTL and a greater than 10-fold increase in the total number of activated (CD44hi) CD8+ T cells during the first week after virus infection. …”
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3312Publicado 1996“…We have therefore directly examined proximal TCR signaling in a CD8+ T cell line in response to various related ligands. …”
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3313por Kehren, Jeanne, Desvignes, Cyril, Krasteva, Maya, Ducluzeau, Marie-Thérèse, Assossou, Olga, Horand, Françoise, Hahne, Michael, Kägi, David, Kaiserlian, Dominique, Nicolas, Jean-François“…We have previously reported that CHS to dinitrofluorobenzene in mice is mediated by major histocompatibility complex (MHC) class I–restricted CD8(+) T cells. In this study, we show that CD8(+) T cells mediate the skin inflammation through their cytotoxic activity. …”
Publicado 1999
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3314
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3315“…In contrast, primed CD8(+) T cells cultured in IL-2 (CD8(IL-2)) become cytotoxic effector cells. …”
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3316por Timm, Joerg, Lauer, Georg M., Kavanagh, Daniel G., Sheridan, Isabelle, Kim, Arthur Y., Lucas, Michaela, Pillay, Thillagavathie, Ouchi, Kei, Reyor, Laura L., zur Wiesch, Julian Schulze, Gandhi, Rajesh T., Chung, Raymond T., Bhardwaj, Nina, Klenerman, Paul, Walker, Bruce D., Allen, Todd M.“…In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8(+) cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. …”
Publicado 2004
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3317por Yang, Liang Peng, Riley, James L., Carroll, Richard G., June, Carl H., Hoxie, James, Patterson, Bruce K., Ohshima, Yusei, Hodes, Richard J., Delespesse, Guy“…CD8(+) T lymphocytes confer significant but ultimately insufficient protection against HIV infection. …”
Publicado 1998
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3318“…Expression of a chimeric human IL-2-receptor-ζ-chain molecule in the CD4(+)8(+) T-cell line, DPK, has enabled us to directly analyze responses initiated by the ζ-chain-signaling module alone within the context of immature T-cell differentiation. …”
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3320por Okazaki, Nobuo, Hasegawa, Kazuya, Ueno, Go, Murakami, Hironori, Kumasaka, Takashi, Yamamoto, Masaki“…In the mail-in data collection system at SPring-8, users pack crystals into sample trays and send the trays to SPring-8 via a courier service as the first step. …”
Publicado 2008
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