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3341por Chodon, Dechen, Guilbert, Arnaud, Dhennin-Duthille, Isabelle, Gautier, Mathieu, Telliez, Marie-Sophie, Sevestre, Henri, Ouadid-Ahidouch, Halima“…BACKGROUND: The calcium-permeable cation channel TRPM8 (melastatin-related transient receptor potential member 8) is over-expressed in several cancers. …”
Publicado 2010
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3342por Kuster, S. P., Drews, S., Green, K., Blair, J., Davis, I., Downey, J., Fowler, R., Katz, K., Lapinsky, S., McRitchie, D., Pataki, J., Powis, J., Rose, D., Sarabia, A., Simone, C., Simor, A., Stewart, T., McGeer, A.“…The purpose of this investigation was to identify when diagnostic testing and empirical antiviral therapy should be considered for adult patients requiring hospitalization during influenza seasons. During the 2007/8 influenza season, six acute care hospitals in the Greater Toronto Area participated in active surveillance for laboratory-confirmed influenza requiring hospitalization. …”
Publicado 2010
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3343
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3344
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3345“…The title compound, C(9)H(7)IN(+)·I(3) (−)·C(4)H(8)O, was synthesized from 8-aminoquinoline using the Sandmeyer reaction. …”
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3346“…The title compound, C(12)H(9)Cl(2)NO(2), was prepared by the esterification of 3,7-dichloroquinoline-8-carboxylic acid with triethyl phosphite. The crystal structure is stabilized by aromatic π–π stacking between the benzene and the pyridine rings of neighbouring molecules [centroid–centroid distances = 3.716 (2) and 3.642 (2) Å]. …”
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3347
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3348
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3349“…We tested the hypothesis that the strength of T cell receptor (TCR) signaling contributed to memory CD8(+) T cell generation. METHODOLOGY/PRINCIPAL FINDINGS: We manipulated the density of antigenic epitope presented by dendritic cells to mouse naïve CD8(+) T cells, without varying TCR affinity. …”
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3350“…The torsion angle of the central S—N—N—C bridge is 144.8 (2)°. The amino group has an intramolecular contact to the quinoline N atom. …”
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3351
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3352“…In the crystal structure of the title compound, C(28)H(20)O(8)S(2), adjacent anthracene skeletons are parallel or inclined at an angle of 20.6 (1)°. …”
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3353por Kitamura, Chitoshi, Tsukuda, Hideki, Kawase, Takeshi, Kobayashi, Takashi, Naito, Hiroyoshi“…The overall molecule has a stair-like shape with the n-butyl groups at the 1 and 8 positions extending towards the same side of the anthracene plane. …”
Publicado 2010
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3354
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3355
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3356
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3357
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3358
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3359“…In the title compound, C(9)H(8)NO(+)·C(3)H(3)O(4) (−), the cation and anion are each essentially planar, with maximum deviations of 0.043 (1) and 0.060 (1) Å, respectively. …”
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3360“…BACKGROUND: The evolutionary tree of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO8P) synthase (KDO8PS), a bacterial enzyme that catalyzes a key step in the biosynthesis of bacterial endotoxin, is evenly divided between metal and non-metal forms, both having similar structures, but diverging in various degrees in amino acid sequence. …”
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