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  1. 3681
    “…We report a case of an 8-year-old boy presenting a posterior hip dislocation after a low-energy trauma, which was initially managed with closed reduction and bed rest for 1 week. …”
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    Recurrent traumatic hip dislocation in an 8-year-old boy
  2. 3682
    “…In order to better understand the T cell-mediated immunological defense in this organ, we aimed to determine phenotypic and functional aspects of CD8 and CD4 T cells present in healthy and allograft kidney tissue. …”
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    CD8 and CD4 T Cell Populations in Human Kidneys
  3. 3683
    “…However, no information is available on ADAM8 expression in cells of the tumor microenvironment. …”
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    Cohort Analysis of ADAM8 Expression in the PDAC Tumor Stroma
  4. 3684
    “…This study evaluates the role of Siglec-8 in breast cancer (BC). Siglec-8 expression was analyzed immunohistochemically on 235 primary BC cases and was correlated with clinical and pathological parameters and outcome. …”
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    First Evidence for a Role of Siglec-8 in Breast Cancer
  5. 3685
    “…The course and outcome of HCV infection is centrally influenced by CD8(+) T cell responses. Indeed, strong virus-specific CD8(+) T cell responses are associated with spontaneous viral clearance while failure of these responses, e.g., caused by viral escape and T cell exhaustion, is associated with the development of chronic infection. …”
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    CD8(+) T Cell Responses during HCV Infection and HCC
  6. 3686
    “…The setup of Symbiotic  8 for Test-Comp  2021 brings radical changes in the test generation for coverage-branches property. …”
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    Symbiotic  8: Parallel and Targeted Test Generation: (Competition Contribution)
  7. 3687
    “…More recently, the role of CD8+ T cells has gained renewed interest. CD8+ T cells are important players in the adaptive immune response against intracellular microorganisms. …”
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    CD8+ T Cells in GCA and GPA: Bystanders or Active Contributors?
  8. 3688
    “…Defective thyroid hormone transport due to deficiency in thyroid hormone transporter monocarboxylate transporter 8 (MCT8) results in severe neurodevelopmental delay due to cerebral hypothyroidism and in clinical negative sequelae following a chronic thyrotoxic state in peripheral tissues. …”
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    Monocarboxylate transporter 8 deficiency: update on clinical characteristics and treatment
  9. 3689
    por Mora-Buch, Rut, Bromley, Shannon K.
    Publicado 2021
    “…Resident memory CD8(+) T (T(RM)) cells are a lymphocyte lineage distinct from circulating memory CD8(+) T cells. …”
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    Discipline in Stages: Regulating CD8(+) Resident Memory T Cells
  10. 3690
    “…Finally, we show that chromosome 8 gain is associated with inferior overall survival in soft-tissue sarcomas. …”
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    Chromosome 8 gain is associated with high-grade transformation in MPNST
  11. 3691
    por Babaev, Eugene V., Shadrin, Ivan A.
    Publicado 2021
    “…Peculiarities of [8+2] cycloaddition of acetylenes to indolizines are reviewed. …”
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    Indolizines and Their Hetero/Benzo Derivatives in Reactions of [8+2] Cycloaddition
  12. 3692
    “…The transcription factor PAX8 is critical for the development of the thyroid and urogenital system. …”
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    PAX8 and MECOM are interaction partners driving ovarian cancer
  13. 3693
    “…Chronic infection with persistent antigenic stimulation results in the generation of exhausted CD8(+) T cells, which are considered defective effector CD8(+) T cells, and thus compromises effective immune responses. …”
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    Transcriptional regulatory network for the establishment of CD8(+) T cell exhaustion
  14. 3694
    “…RESULTS: In ‘true‐CM’ subjects, MMP8 staining was invariably associated with sequestered parasites and a median of 88% (IQR = 74–91%) of capillaries showed MMP8 staining, compared with 14% (IQR = 3.8–24%) in ‘faux‐CM’ (P‐value = 0.001). 41% (IQR = 28–49%) of capillaries in ‘true‐CM’ subjects showed co‐localisation of extravascular fibrinogen leak and MMP8 staining, compared with 1.8% of capillaries in ‘faux‐CM’ (IQR = 0–3.9%, P‐value = 0.01). …”
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    Localised release of matrix metallopeptidase 8 in fatal cerebral malaria
  15. 3695
    “…Background: Somatic mutations in the ubiquitin-specific peptidase 8 (USP8) gene have been described in Cushing’s disease (CD). …”
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    USP8 Somatic Mutations in Cushing’s Disease and Silent Corticotropinomas
  16. 3696
    “…BACKGROUND: Streptococcus pneumoniae serotype 8 incidence has increased in Denmark after the introduction of pneumococcal conjugated vaccines (PCV). …”
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    Molecular characterization and epidemiology of Streptococcus pneumoniae serotype 8 in Denmark
  17. 3697
    “…Here we use complementary long-read sequencing technologies to complete the linear assembly of human chromosome 8. Our assembly resolves the sequence of five previously long-standing gaps, including a 2.08-Mb centromeric α-satellite array, a 644-kb copy number polymorphism in the β-defensin gene cluster that is important for disease risk, and an 863-kb variable number tandem repeat at chromosome 8q21.2 that can function as a neocentromere. …”
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    The structure, function and evolution of a complete human chromosome 8
  18. 3698
    “…In summary, these results point out transient changes in TRPM8 activity early after oxaliplatin treatment and a later occurring TRPM8 channel desensitization in primary sensory neurons. …”
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    Oxaliplatin Causes Transient Changes in TRPM8 Channel Activity
  19. 3699
    “…Here we present new mechanistic data highlighting the role of hypoxia in fine-tuning CD8 T cell exhaustion in vitro, in an attempt to reconcile seemingly opposite evidence regarding the impact of hypoxia on functional features of exhausted CD8 T cells. …”
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    Hypoxia Supports Differentiation of Terminally Exhausted CD8 T Cells
  20. 3700
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    Facial Trauma 8 years after a Face Transplantation
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