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  1. 3821
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    Microwave produced 8-methyl-1,2,4,8-tetraazaspiro[4.5]dec-2-en-3-amine derivatives: their in vitro and in silico analysis
  2. 3822
    “…Caspase recruitment containing domain 8 (CARD8) is a negative regulator of NLRP3 inflammasome and also an inhibitor of transcription factor NFĸB, a major transcription factor of proinflammatory cytokines. …”
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    Variants of CARD8 in Leishmania guyanensis-cutaneous leishmaniasis and influence of the variants genotypes on circulating plasma cytokines IL-1β, TNFα and IL-8
  3. 3823
    “…Cumulative studies have indicated involvement of CD8-positive (CD8(+)) cells, including virus-specific CD8(+) T cells in the control of HTLV-1 replication. …”
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    HTLV-1 Proliferation after CD8(+) Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques
  4. 3824
    “…Here, we study the trans-splicing of CPE intein obtained from the directed evolution of Cne PRP8, which shows that its splicing rate is ~29- fold higher than that of the wild-type. …”
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    Efficient splicing of the CPE intein derived from directed evolution of the Cryptococcus neoformans PRP8 intein : Directed evolution of the Cryptococcus neoformans PRP8 intein
  5. 3825
    “…Co‐localization of CD8+FOXP3+ with CD4+CD8+ cells is predictors of time to relapse independent of the FLIPI score and density of CD8+FOXP3+ cells (p = 0.027, HR = 0.0019 [7.19 × 10(−6), 0.49], This suggests a potential role of inter‐follicular CD8+FOXP3+ and CD4+CD8+ cells in the disease progression of FL, warranting further validation on larger patient cohorts.…”
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    High inter‐follicular spatial co‐localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma
  6. 3826
    Publicado 1996
    “…Expansion of mature neutrophils has been observed in mice lacking the murine interleukin (IL) 8 receptor homolog [mIL-8Rh(-/-)], and human (hu) IL-8 suppresses proliferation of primitive myeloid cells in vitro and in vivo. …”
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    Involvement of Interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: evidence from mice lacking the murine IL-8 receptor homologue
  7. 3827
    “…Dendritic cells (DCs) activated by CD40L-expressing CD4(+) T cells act as mediators of “T helper (Th)” signals for CD8(+) T lymphocytes, inducing their cytotoxic function and supporting their long-term activity. …”
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    Complementary Dendritic Cell–activating Function of CD8(+) and CD4(+) T Cells: Helper Role of CD8(+) T Cells in the Development of T Helper Type 1 Responses
  8. 3828
    “…The release of eotaxin-1, CXCL-8 or GMCSF was measured by ELISA. RESULTS: Gram-negative E. coli or Gram-positive S. aureus increased the release of CXCL-8, as did IL-1β, LPS, FSL-1 and Pam(3)CSK4, whereas FK565, MODLys18 or Poly I:C did not. …”
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    Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells
  9. 3829
    “…RESEARCH DESIGN AND METHODS—Phosphorylation of Akt and tuberin, 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) levels, and 8-oxoG-DNA glycosylase (OGG1) expression were measured in kidney cortical tissue of control and type 1 diabetic animals and in proximal tubular cells incubated with normal or high glucose. …”
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    Mechanism of Oxidative DNA Damage in Diabetes : Tuberin Inactivation and Downregulation of DNA Repair Enzyme 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine-DNA Glycosylase
  10. 3830
    “…Prior to treatment, HIV-1 Gag–specific CD8+ T cells were predominantly of a highly activated, intermediate memory (CD27+CD28−) phenotype, while CMV pp65-specific CD8+ T cells showed a late memory (CD27−CD28−), low activation phenotype. …”
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    High CD8+ T Cell Activation Marks a Less Differentiated HIV-1 Specific CD8+ T Cell Response that Is Not Altered by Suppression of Viral Replication
  11. 3831
    “…BACKGROUND: Human herpesvirus 8 (HHV-8) is the etiological agent for Kaposi Sarcoma, which occurs especially in HIV-infected subjects. …”
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    High Human Herpesvirus 8 (HHV-8) Prevalence, Clinical Correlates and High Incidence among Recently HIV-1-Infected Subjects in Sao Paulo, Brazil
  12. 3832
    “…The class III sugar transport facilitator GLUT8 co-localizes with the lysosomal protein LAMP1 in heterologous expression systems. …”
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    Lysosomal localization of GLUT8 in the testis – the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction
  13. 3833
    por Takada, Kensuke, Jameson, Stephen C.
    Publicado 2009
    “…Previous studies have suggested that naive CD8 T cells require self-peptide–major histocompatability complex (MHC) complexes for maintenance. …”
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    Self–class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels
  14. 3834
    por Chen, Zhu-Jun, Lei, Ke-Wei
    Publicado 2008
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    4,4′,6,6′-Tetra­bromo-2,2′-(2,8-diazonia-5-azanona-1,8-diene-1,9-diyl)diphenolate
  15. 3835
    por Wang, Min, Zhou, Hong-Bo, Chen, You-Cun
    Publicado 2008
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    A charge-transfer salt, 3,5-dimethyl-1-(4-nitro­benz­yl)pyridinium 7,7,8,8-tetra­cyano­quinodimethane
  16. 3836
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    7-Bromo-4b-methyl-7,8-dihydro-4bH-9-thia-8a-aza­fluorene 9,9-dioxide
  17. 3837
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    2,8-Dimethyl­tricyclo­[5.3.1.1(3,9)]dodecane-syn-2,syn-8-diol–propanoic acid (1/1)
  18. 3838
    “…The reaction of zinc chloride and 2-methyl-8-hydroxy­quinoline in methanol yielded the title monosolvated salt, (C(10)H(10)NO)[ZnCl(2)(C(10)H(8)NO)]·CH(3)OH, which has the Zn atom within a distorted Cl(2)NO tetra­hedral coordination geometry. …”
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    8-Hydr­oxy-2-methyl­quinolinium dichlorido(2-methyl­quinolin-8-olato-κ(2) N,O)zincate(II) methanol solvate
  19. 3839
    “…The anion of the title salt, (C(10)H(10)NO)[Zn(C(10)H(8)NO)I(2)]·CH(3)OH, has its metal atom N,O-chelated by the deprotonated 2-methyl-8-hy­droxy­quinoline ligand. …”
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    8-Hy­droxy-2-methyl­quinolinium diiodido(2-methyl­quinolin-8-olato-κ(2) N,O)zincate(II) methanol monosolvate
  20. 3840
    “…The anion of the title salt, (C(10)H(10)NO)[ZnBr(2)(C(10)H(8)NO)]·CH(3)OH, has its metal atom N,O-chelated by the deprotonated 2-methyl-8-hy­droxy­quinoline ligand. …”
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    8-Hy­droxy-2-methyl­quinolinium dibromido(2-methyl­quinolin-8-olato-κ(2) N,O)zincate(II) methanol monosolvate
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