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  1. 3841
    “…In the brain, PSA is exclusively synthesized by the two polysialyltransferases ST8SiaII (also known as STX) and ST8SiaIV (also known as PST). …”
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    Sensory Experience Differentially Modulates the mRNA Expression of the Polysialyltransferases ST8SiaII and ST8SiaIV in Postnatal Mouse Visual Cortex
  2. 3842
    “…The reaction of 2-methyl-8-hy­droxy­quinoline and zinc bromide in acetonitrile affords the title solvated salt, (C(10)H(10)NO)[ZnBr(2)(C(10)H(8)NO)]·CH(3)CN, in which the Zn(II) ion is coordinated by a N,O-chelating 2-methyl­quinolin-8-olate ligand and two bromide ligands in a distorted tetra­hedral geometry. …”
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    8-Hy­droxy-2-methyl­quinolinium dibromido(2-methyl­quinolin-8-olato-κ(2) N,O)zincate acetonitrile mono­solvate
  3. 3843
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    4-(4-Chloro­phen­yl)-8-methyl-2-oxo-1,2,5,6,7,8-hexa­hydro­quinoline-3-carbonitrile
  4. 3844
    “…Relative amounts followed a CD8α>DN>CD4 pattern for Th1 and CD4>DN>CD8α for Th2. …”
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    Distinct and Overlapping Effector Functions of Expanded Human CD4(+), CD8α(+) and CD4(-)CD8α(-) Invariant Natural Killer T Cells
  5. 3845
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    (2R)-8-Benzyl-2-[(S)-hy­droxy(phen­yl)meth­yl]-8-aza­bicyclo­[3.2.1]octan-3-one
  6. 3846
    “…Here, we demonstrate for the first time that mouse plasmacytoid DCs (pDCs) can be segregated into three distinct populations, exhibiting phenotypic and functional differences, according to their surface expression of CD8α or CD8β as CD8α(−)β(−), CD8α(+)β(−) or CD8α(+)β(+). …”
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    CD8α(+)β(−) and CD8α(+)β(+) plasmacytoid dendritic cells induce Foxp3(+) regulatory T cells and prevent the induction of airway hyperreactivity
  7. 3847
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    8-Methyl-2-oxo-4-(thio­phen-2-yl)-1,2,5,6,7,8-hexa­hydro­quinoline-3-carbonitrile
  8. 3848
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    Loss and regain of SIV control upon CD8+ cell depletion in vivo in SIV-controller macaques is not associated with efficient SIV specific CD8+ T-cells
  9. 3849
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    2,2,7,7-Tetra­methyl-1,2,3,4,5,6,7,8-octa­hydro­acridine-1,8-dione
  10. 3850
    “…TLR8 promoter-luciferase reporter assays indicated that 1,25(OH)(2)D(3) decreases TLR8 mRNA level in part via inhibiting TLR8 gene transcription activity. …”
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    1,25-Dihydroxyvitamin D3 Suppresses TLR8 Expression and TLR8-Mediated Inflammatory Responses in Monocytes In Vitro and Experimental Autoimmune Encephalomyelitis In Vivo
  11. 3851
    “…That study identified frequently recurring gains and losses involving chromosome bands 8q22 and 8p21, respectively. Moreover, these data highlighted an association between 8q22 gain and typically aggressive grade 3 tumors. …”
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    Dual-Color Fluorescence In Situ Hybridization Reveals an Association of Chromosome 8q22 but Not 8p21 Imbalance with High Grade Invasive Breast Carcinoma
  12. 3852
    “…Although the association of rs2709722 in Sp8 transcription factor (SP8) was suggestive in the Asian population (P = 2.1×10(−7) for psychosis), this signal weakened when the samples size was increased by including data from a Caucasian population (P = 4.3×10(−3)). …”
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    Genetic Variants on 3q21 and in the Sp8 Transcription Factor Gene (SP8) as Susceptibility Loci for Psychotic Disorders: A Genetic Association Study
  13. 3853
    “…Although PEL occurs in immunocompromised patients that are human immunodeficiency virus (HIV) positive, it also occurs in immunocompetent human herpes virus-8 (HHV-8)-positive patients. Herein we present an immunocompetent, HIV-negative, CD-20-negative, HHV-8-positive patient with pleural effusion that was diagnosed as PEL. …”
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    Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature
  14. 3854
    “…In the study described herein, 25 rhesus macaques received prime and boost intramuscular (IM) immunizations of AdPfCA alone or with an ascending dose of 7DW8-5. Our results indicate that 7DW8-5 is safe and well-tolerated and provides a significant enhancement (up to 9-fold) in malaria-specific CD8+ T-cell responses after both priming and boosting phases, supporting further clinical development.…”
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    A Glycolipid Adjuvant, 7DW8-5, Enhances CD8+ T Cell Responses Induced by an Adenovirus-Vectored Malaria Vaccine in Non-Human Primates
  15. 3855
    “…BACKGROUND: Increased infiltration of CD8(+)T cells into tumors has a positive impact on survival. …”
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    CD8(+)T cell–specific induction of NKG2D receptor by doxorubicin plus interleukin-12 and its contribution to CD8(+)T cell accumulation in tumors
  16. 3856
    “…To evaluate the effectiveness and safety of perfluorohexyloctane (F6H8) for intraoperative flattening of the retina and of F6H8/silicone oil (SO) 1000 cSt as a postoperative tamponade for inferior retinal detachment with inferior proliferative vitreoretinopathy. …”
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    F6H8 as an Intraoperative Tool and F6H8/Silicone Oil as a Postoperative Tamponade in Inferior Retinal Detachment with Inferior PVR
  17. 3857
    “…BACKGROUND: In order to gain further insight on the crosstalk between pancreatic cancer (PDAC) and stromal cells, we investigated interactions occurring between TGFβ1 and the inflammatory proteins S100A8, S100A9 and NT-S100A8, a PDAC-associated S100A8 derived peptide, in cell signaling, intracellular calcium (Ca(i)(2+)) and epithelial to mesenchymal transition (EMT). …”
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    Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1
  18. 3858
    “…Among lymph DCs (LDCs) only CD103(+) CD11b(−) CD8α(+) DCs cross-present IEC-derived ovalbumin to CD8(+) OT-I T cells. …”
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    Lymph-borne CD8α(+) dendritic cells are uniquely able to cross-prime CD8(+) T cells with antigen acquired from intestinal epithelial cells
  19. 3859
    “…TLR7 and TLR8 recognize RNA from pathogens and lead to subsequent immune stimulation. …”
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    A Single Naturally Occurring 2’-O-Methylation Converts a TLR7- and TLR8-Activating RNA into a TLR8-Specific Ligand
  20. 3860
    “…BACKGROUND: Previous studies have shown that angiopoietin-like protein 8 (ANGPTL8), also called as betatrophin, acts together with ANGPTL3 to regulate lipid metabolism, glucose metabolism, and energy homeostasis. …”
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    Circulating angiopoietin-like protein 8 (ANGPTL8) and ANGPTL3 concentrations in relation to anthropometric and metabolic profiles in Korean children: a prospective cohort study
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