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  1. 4441
  2. 4442
  3. 4443
  4. 4444
    por Cox, Maureen A., Zajac, Allan J.
    Publicado 2010
    “…CD8 T cells play a vital role in the immunological protection against intracellular pathogens. …”
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  5. 4445
    “…Vaccines intended to induce a cytotoxic CD8+ T-cell response are highly sought after. However, some of these vaccines can be problematic if they replicate in the host. …”
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  6. 4446
  7. 4447
  8. 4448
    “…By comparing the barcodes present in antigen-specific effector and memory T cell populations in systemic and local infection models, at different anatomical sites, and for TCR–pMHC interactions of different avidities, we demonstrate that under all conditions tested, individual naive T cells yield both effector and memory CD8(+) T cell progeny. This indicates that effector and memory fate decisions are not determined by the nature of the priming antigen-presenting cell or the time of T cell priming. …”
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  9. 4449
  10. 4450
    “…In this cross-sectional study, we evaluated plasma 8-hydroxydeoxyguanosine (8-OHdG) levels in patients with colorectal adenoma and cancer, as a surrogate marker of oxidative damage to deoxyribonucleic acid (DNA). …”
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  11. 4451
  12. 4452
    “…Rapid mobilization of neutrophils from vasculature to the site of bacterial/viral infections and tissue injury is a critical step in successful resolution of inflammation. The chemokine CXCL8 plays a central role in recruiting neutrophils. …”
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  13. 4453
  14. 4454
    “…The plane of the acetyl­amino group is slightly inclined [11.7 (2)°] to the plane of the 1,8-naphthyridine ring.…”
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  15. 4455
    “…The title compound, C(18)H(12)N(2)O(2)·0.5H(2)O, was prepared by the reaction of 1,4-phenyl­enediamine with 1,8-naphthalic anhydride in refluxing dimethyl­formamide. …”
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  16. 4456
    “…Following a switch from variant surface glycoprotein MITat1.4 to variant surface glycoprotein MITat1.8 expression by Lister strain 427 Trypanosoma brucei brucei parasites, the latter uncharacterized variant surface glycoprotein was analysed. …”
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  17. 4457
    “…We found that ADAM8 was expressed in murine thymic stromal cells and at lower levels in thymocytes where its expression increased as cell matured, suggesting involvement of ADAM8 in thymopoiesis. …”
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  18. 4458
    “…BACKGROUND: We have examined the phylogenetic pattern among eukaryotes of homologues of the E. coli 7,8-dihydro-8-oxoguanine (8-oxo-G) repair enzymes MutY, MutM, and MutT. …”
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  19. 4459
    “…Here we examined the allelopathic potential of 8-hydroxyquinoline (HQ), a chemical reported to be exuded from the roots of Centaurea diffusa. …”
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  20. 4460
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