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  1. 926761
    por Jácome, Cristina, Almeida, Rute, Pereira, Ana Margarida, Amaral, Rita, Mendes, Sandra, Alves-Correia, Magna, Vidal, Carmen, López Freire, Sara, Méndez Brea, Paula, Araújo, Luís, Couto, Mariana, Antolín-Amérigo, Darío, de la Hoz Caballer, Belén, Barra Castro, Alicia, Gonzalez-De-Olano, David, Todo Bom, Ana, Azevedo, João, Leiria Pinto, Paula, Pinto, Nicole, Castro Neves, Ana, Palhinha, Ana, Todo Bom, Filipa, Costa, Alberto, Chaves Loureiro, Cláudia, Maia Santos, Lilia, Arrobas, Ana, Valério, Margarida, Cardoso, João, Emiliano, Madalena, Gerardo, Rita, Cidrais Rodrigues, José Carlos, Oliveira, Georgeta, Carvalho, Joana, Mendes, Ana, Lozoya, Carlos, Santos, Natacha, Menezes, Fernando, Gomes, Ricardo, Câmara, Rita, Rodrigues Alves, Rodrigo, Moreira, Ana Sofia, Bordalo, Diana, Alves, Carlos, Ferreira, José Alberto, Lopes, Cristina, Silva, Diana, Vasconcelos, Maria João, Teixeira, Maria Fernanda, Ferreira-Magalhães, Manuel, Taborda-Barata, Luís, Cálix, Maria José, Alves, Adelaide, Almeida Fonseca, João
    Publicado 2021
    “…RESULTS: A total of 107 patients (median 27 [P25-P75 14-40] years) were invited, 92.5% (99/107) installed the app, and 73.8% (79/107) completed the 1-month interview. Patients interacted with the app a median of 9 (P25-P75 1-24) days. …”
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    Feasibility and Acceptability of an Asthma App to Monitor Medication Adherence: Mixed Methods Study
  2. 926762
    por Guo, Fengxia, Sha, Yanhua, Hu, Bing, Li, Gang
    Publicado 2021
    “…In addition, positive correlations were found between the Gensini score and TNF-α, MCP-1, VCAM-1, ICAM-1, and IL-6 in CHD patients. (5) LncRNA-FA2H-2 relative expression in the CHD group was significantly downregulated (P < 0.001). (6) The differences in the expression levels of LncRNA-FA2H-2 were statistically significant between the two comparative analyses (P < 0.01), except between the 2-branch lesion and 3-branch lesion groups. (7) LncRNA-FA2H-2 was not associated with age, sex, hypertension, diabetes, smoking, drinking, BMI, WBC, TG, TC, LDL-C, HDL-C, and ApoA1 (P > 0.05). (8) A correlation was found between LncRNA-FA2H-2 and MCP-1, and VCAM-1, ICAM-1, IL-6, and Gensini. (9) The results indicated that the relative levels of LncRNA-FA2H-2 between the two comparative analyses (high risk, moderate risk, and low risk groups) were statistically significant. …”
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    Correlation of Long Non-coding RNA LncRNA-FA2H-2 With Inflammatory Markers in the Peripheral Blood of Patients With Coronary Heart Disease
  3. 926763
    “…Notably, the joint effect of PCOS/anovulatory infertility and BMI-based pre-pregnancy obesity on offspring obesity (HR 8.89; 95% CI 7.06–11.20) was larger than that of either PCOS/anovulatory infertility or obesity alone. …”
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    Association of maternal polycystic ovary syndrome or anovulatory infertility with obesity and diabetes in offspring: a population-based cohort study
  4. 926764
    “…FINDINGS: After exclusion of 9210 (1·8%) of the 502 505 participants in the UK Biobank cohort, our study sample comprised 493 295 individuals. …”
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    Non-communicable disease, sociodemographic factors, and risk of death from infection: a UK Biobank observational cohort study
  5. 926765
    “…Nous avons noté une amélioration significative des SM des connaissances des PS sur le rôle des mains dans la transmission croisée des micro-organismes (65,97 ± 17,75 vs 79,16 ± 13,57 ; p < 0,001) ainsi que des différentes techniques de l’HDM (47,97 ± 12,67 vs 67,38 ± 8,59 ; p < 0,001). Concernant la source la plus fréquente d’acquisition des IAS, le SM des connaissances est resté stable (32,14 ± 6,73 vs 48,21 ± 6,45 ; p = 0,058). …”
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    Évaluation de l’efficacité d’une stratégie multimodale sur les connaissances et les perceptions des professionnels de santé en matière d’hygiène des mains en phase pandémique COVID-19 : une étude quasi-expérimentale
  6. 926766
    “…Au cours des semaines 13 à 16 de 2018, 2019 et 2020, l’âge médian de tous les résidents était de 90,0 [IQR : 85,0–94,0], 89,0 [IQR : 84,0–93,0] et 89,0 [IQR : 83,0–93,0], tandis que l’âge médian des résidents décédés était de 89,0 [IQR : 86,0–96,0], 91,0 [IQR : 88,0–95,0] et 89,0 [IQR : 84,0–93,8], respectivement. Au cours de ces semaines, le sex-ratio (M/F) dans l’ensemble de la cohorte était de 0,33 en 2018, 0,36 en 2019 et 0,36 en 2020. …”
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    Surmortalité dans les maisons de retraite pendant la pandémie de COVID-19
  7. 926767
    “…À l’inverse, parmi les professionnels originaires de métropole ou de l’étranger, elle n’était pas différente en fonction de l’ancienneté d’arrivée en Guyane (qui était en médiane de 8 ans, IIQ [19–2]). Elle ne variait pas non plus en fonction du lieu d’exercice. …”
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    Attitudes vis-à-vis du vaccin COVID-19 des soignants exerçant en Guyane française
  8. 926768
    “…SARS-CoV-2 infection in beta thalassemia: Preliminary data from the Italian experience. Am J Hematol. 2020;95(8): E198-E199. 3. https://www.epicentro.iss.it/coronavirus/sars-cov-2-dashboard, Accessed July 31, 2020 4. …”
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    COVID 19 and Hemoglobinopathies: Update of the Italian Experience
  9. 926769
    “…Lymphopenia was a consistent finding at diagnosis (median lymphocyte count 0.8 x 10(9)/l), neutropenia was rare (median neutrophil count 5.9 x 10(9)/l) and C-reactive protein was elevated in all cases (median value 169, range 42-473 mg/l). …”
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    A Large London District General Hospital Highlights CLL and Bame As Risk Factors for Severe Disease Amongst Haematology-Oncology Patients
  10. 926770
    “…Ethnicity was White, Asian-Indian, Black in 8 (44.4%), 6 (33%) and 4 (22.2%), respectively. …”
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    Prevalence of Sars-Cov-2 Infection in Patients with Chronic Myeloid Leukemia
  11. 926771
    “…S protein lessens functional HPC colony forming cell expansion compared to control, with 12-fold and 2.1-fold expansions compared to 30.8-fold and 6-fold expansions respectively for CFU-GM and CFU-GEMM. …”
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    Sars-Cov-2 Spike Protein Induces Cellular Changes in Primitive and Mature Hematopoietic Cells
  12. 926772
    “…More than half (13/21, 62%) of patients received some COVID-19 directed therapy, while 8 were treated with supportive care alone. As of July 15, 2020 18/21 (86%) patients were alive. …”
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    COVID-19 in Patients with Hematologic Malignancies: A Single-Center Experience
  13. 926773
    “…Direct oral anticoagulants (DOACS) were infrequently recommended (3.8% for SCD children and 10.9% for adults); of these, rivaroxaban was used most often. …”
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    Venous Thromboembolism Prophylaxis Practices for Patients with Sickle Cell Disease Pre and during the COVID-19 Pandemic
  14. 926774
    “…Lastly, our institution had a significantly decreased mortality rate compared to the ASH RC (11.5% versus 29.8%, P=.049). Demographics as well as type and status of hematologic malignancy comparing the two cohorts are shown in Table 1. …”
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    Outcomes of COVID-19 Infection in Patients with Hematologic Malignancies
  15. 926775
    “…Twenty-two pts had a HM: plasma cell dyscrasia (n=7, 31.8%; multiple myeloma n=6, MGUS n=1), chronic lymphocytic leukemia (n=3, 13.6%), chronic myelomonocytic leukemia (n=2, 9.1%), diffuse large B-cell lymphoma (n=2, 9.1%), hodgkin’s lymphoma (n=2, 9.1%), and one patient (4.5%) with each of the following malignancies: acute promyelocytic leukemia, anaplastic large cell lymphoma, B-cell lymphoma not otherwise specified, follicular lymphoma, mantle cell lymphoma and marginal zone lymphoma. …”
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    Clinical Outcomes in Patients with Hematologic Malignancy (HM) and COVID-19
  16. 926776
    “…With this technique, production of anti-S and anti-N antibodies has been demonstrated between day 8 and day 14 after onset of symptoms in immunocompetent individuals, whereas specific antibody production was delayed by few days in immunocompromised patients (Burbelo PD et al, medRxiv. 2020 Apr 24:2020.04.20.20071423). …”
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    Impaired Sars-Cov-2 Specific Antibody Responses in Patients Treated with Anti-CD20 Antibodies
  17. 926777
    “…The mean age of participants was 57·8 years (SD 4·7), with 212 (46%) female participants and 117 (25%) from ethnic minorities. …”
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    Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial
  18. 926778
    “…METHODS: Fifty-two healthy volunteers (from May 2019 to August 2019, age from 28 to 68 years, 23 males and 29 females (age: 40 ± 8 years; weight: 68.3 ± 5.2 kg; height: 170.2 ± 13.1 cm) were recruited, and lumbodorsal muscle, including the multifidus, longissimus, iliocostalis, and quadratus lumborum, ultrasonic examinations were carried out in the relaxed and contracted states. …”
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    Dynamic evaluation of the contractile function of lumbodorsal muscles during locust pose in yoga by real-time ultrasound
  19. 926779
    “…The proliferation of breast cancer cells was monitored by CCK8 cell proliferation assay, and the migration and invasion of breast cancer cells was observed by cell scratch test and transwell assay. …”
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    AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway
  20. 926780
    “…The hospital stay time for patients in Arm I was significantly longer (mean [SD]=8.4 [2.0] days) as compared to the Arms II and III (mean [SD]=4.7 [1.5] and 4.2 [1.5] days, respectively (Kruskal-Wallis test, P=0.0001). …”
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    Efficacy of two siddha polyherbal decoctions, Nilavembu Kudineer and Kaba Sura Kudineer, along with standard allopathy treatment in the management of mild to moderate symptomatic COVID-19 patients—a double-blind, placebo-controlled, clinical trial
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