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926801por Mozaffari, Essy, Chandak, Aastha, Zhang, Zhiji, Liang, Shuting, Thrun, Mark, Gottlieb, Robert L, Kuritzkes, Daniel R, Sax, Paul, Wohl, David, Casciano, Roman, Hodgkins, Paul, Haubrich, Richard“…Mortality in RDV patients was 9.6% and 13.8% on days 14 and 28, respectively. For non-RDV patients, mortality was 14.0% and 17.3% on days 14 and 28, respectively. …”
Publicado 2021
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926802por Rolle, Charlotte-Paige M, Berhe, Mezgebe, Singh, Tulika, Ortiz, Roberto, Wurapa, Anson K, Ramgopal, Moti, Jayaweera, Dushyantha, Leone, Peter, Matthews, Jessica, Cupo, Michael, Underwood, Mark, Angelis, Kostas, Wynne, Brian, Merrill, Deanna, Nguyen, Christopher T, van Wyk, Jean A, Zolopa, Andrew“…Of the 9 participants with baseline VL ≥ 1,000,000 c/mL with available data through Week 48, most participants (8/9; 89%) were suppressed by Week 24. Figure 1. …”
Publicado 2021
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926803por Zhou, Dan-Dan, Bai, Wei-Qi, Zhai, Xiao-Tian, Sun, Li-Ping, Zhen, Yong-Su, Li, Zhuo-Rong, Miao, Qing-Fang“…MDA-MB-468 and MDA-MB-231 cells were treated with LR004-VC-MMAE (0, 0.0066, 0.066, 0.66, 6.6 nmol/L), and the inhibitory effects of LR004-VC-MMAE on cell proliferation were examined by CCK-8 and colony formation. The migration and invasion capacity of MDA-MB-468 and MDA-MB-231 cells were tested at different LR004-VC-MMAE concentrations (2.5 and 5 nmol/L) with wound healing and Transwell invasion assays. …”
Publicado 2021
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926804por Francisco, Michael T., Kaufman, Adrienne E., Northfelt, Donald, Padrnos, Leslie, Rosenthal, Allison C., Andres, Jennifer, Adamski, Jill, Kinard, Theresa, Camoriano, John“…He was again hospitalized and underwent 8 sessions of daily TPE, as well as re-initiation of caplacizumab, mycophenolate mofetil 500 mg bid (with increasing taper), and a prednisone taper. …”
Publicado 2021
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926805por Goldberg, Rachel N., Johns, Kevin, Ye, William, Mucksavage, Jeff J., Quigley, John G., Shapiro, Nancy L., Benken, Scott T., Atal, Neha, Jacobson, Jeffrey R., Kim, Keri S.“…There was a significantly higher incidence of use of renal replacement therapy (8.5% vs 0%, p=0.016) and mortality (15.6% vs 3.4%, p=0.048) in the SARS-CoV-2 PNA group compared to the H3N2/H1N1 PNA group. …”
Publicado 2021
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926806por Clemenceau, Beatrice, Guillaume, Thierry, Coste-Burel, Marianne, Peterlin, Pierre, Garnier, Alice, Le Bourgeois, Amandine, Imbert, Berthe-Marie, Drumel, Thomas, Mahé, Béatrice, Dubruille, Viviane, Blin, Nicolas, Lok, Anne, Touzeau, Cyrille, Gastinne, Thomas, Tessoulin, Benoit, Jullien, Maxime, Vantyghem, Sophie, Ollier, Jocelyn, Bene, Marie C, Moreau, Philippe, Le Gouill, Steven, Vie, Henri, Chevallier, Patrice“…Among these humoral responders (HR), 89% (n=32/36) also had a positive anti-spike T-cell response with variable frequencies (median =119 SFU/10 (6) T-cells. For 8 patients, this T cell response was higher than that of controls (>800 SFU/10 (6) T-cells) (Figure 1), which is equivalent to more than 1 specific T-cell per microliter of blood (Figure 2). …”
Publicado 2021
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926807por Goel, Shipra, Gu, Juan J., Torka, Pallawi, Mavis, Cory, Sundaram, Suchitra, Neiders, Mirdza, Suresh, Lakshmanan, Shen, Long, Ramsperger, Vince, Griffiths, Elizabeth A., Segal, Brahm, Hernandez-Ilizaliturri, Francisco J., Ghione, Paola“…Baseline N count (p= 0.5), sex (p= 0.2), age (p= 0.8), number of prior lines of treatment (p= 0.4), type of disease (p= 0.7), time from end of BCT to vaccine (p= 0.7) and type of vaccine (p= 0.08), did not affect the rate of seroconversion. …”
Publicado 2021
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926808por Zhang, Ziyu, Dai, Wen, Zhu, Wen, Rodriguez, Maya, Rau, Mary, Lund, Hayley, Baumann Kreuziger, Lisa, Wen, Renren, Silverstein, Roy L., Zheng, Ze“…The plasma apo(a) concentration is significantly higher in SARS-CoV-2-positive inpatients than in the plasma from SARS-CoV-2-negative inpatients (the median of the two groups are 114.8 versus 34.4 μg/mL, p<0.05) (Figure B). Among the 20 hospitalized patients with COVID-19, 13 survived. …”
Publicado 2021
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926809por Badawy, Sherif M., DiMartino, Lisa, Brambilla, Donald, Baumann, Ana, Burns, Ebony, Demartino, Theresa, Jacobs, Sara, Khan, Hamda, Klesges, Lisa, Kutlar, Abdullah, Nwosu, Chinonyelum, Shah, Nirmish, Hankins, Jane S“…Eleven patients (mean age 26.2 years old, 64% males, 100% Black, 73% HbSS, 45% low app users) and 11 providers (mean age 36.7 years old, 73% females, 36% Black, 54.5% physicians, average 8 years in practice, 36% low app users) completed the semi-structured interviews across the 2 sites. …”
Publicado 2021
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926810por Aumann, Shlomzion, Tsubary, Uria, Israel, Sarah, Ben Yehuda, Dina, Lavie, David, Goldschmidt, Neta, Vainstein, Vladimir, Libster, Diana, Saban, Revital, Shaulov, Adir, Avni, Batia, Nachmias, Boaz, Grisariu, Sigal, Paltiel, Ora, Gatt, Moshe, Zimran, Eran“…Overall mortality, severe COVID-19, and hospitalization rates in the entire group were 9.8%, 14.2% and 32%, respectively, remarkably lower than in previous reports. …”
Publicado 2021
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926811por Saraceni, Francesco, Fiorentini, Alessandro, Morè, Sonia, Guerzoni, Selene, Puglisi, Bruna, Corvaro, Benedetta, Caucci, Sara, Menzo, Stefano, Costantini, Andrea, Butini, Luca, Viola, Nadia, Scortechini, Ilaria, Mancini, Giorgia, Dubbini, Maria Vittoria, Federici, Irene, Kordasti, Shahram, Offidani, Massimo, Patriarca, Francesca, Battista, Marta Lisa, Chiarucci, Martina, Visani, Giuseppe, Falcioni, Sadia, Galieni, Piero, Natale, Annalisa, Vaddinelli, Doriana, Santarone, Stella, Colasante, Fabrizia, Carella, Angelo Michele, Battipaglia, Giorgia, Pane, Fabrizio, Olivieri, Attilio“…HSCT recipients showed lower antibody titers (median 1.8 BAU, range 0-481) as compared to healthy controls (median 118 BAU, range 6-1172, p<0.01). …”
Publicado 2021
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926812por Miller, Karin Paige, Brown, Patrick A., Smith, B. Douglas, Webster, Jonathan, Powell, Helen, Duffield, Amy S.“…During the same 90 day period in 2019, there were 32 new diagnoses of AL (18 women/14 men) with a median age of 63 years (range: 8 - 93 years; 2 pediatric/30 adult). Figure 1 shows the distribution of new AL diagnoses in adult patients by date of presentation. …”
Publicado 2021
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926813por Tseng, Ting-En, Lee, Chia-Che, Yen, Hung-Kuan, Groot, Olivier Q., Hou, Chun-Han, Lin, Shin-Ying, Bongers, Michiel E. R., Hu, Ming-Hsiao, Karhade, Aditya V., Ko, Jia-Chi, Lai, Yi-Hsiang, Yang, Jing-Jen, Verlaan, Jorrit-Jan, Yang, Rong-Sen, Schwab, Joseph H., Lin, Wei-Hsin“…In general, a c-index of 0.5 indicates random guess and a c-index of 0.8 denotes excellent discrimination. Calibration refers to the agreement between the predicted outcomes and the actual outcomes, with a perfect calibration having an intercept of 0 and a slope of 1. …”
Publicado 2022
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926814por van Hoogenhuijze, N E, van Eekelen, R, Mol, F, Schipper, I, Groenewoud, E R, Traas, M A F, Janssen, C A H, Teklenburg, G, de Bruin, J P, van Oppenraaij, R H F, Maas, J W M, Moll, E, Fleischer, K, van Hooff, M H A, de Koning, C H, Cantineau, A E P, Lambalk, C B, Verberg, M, van Heusden, A M, Manger, A P, van Rumste, M M E, van der Voet, L F, Pieterse, Q D, Visser, J, Brinkhuis, E A, den Hartog, J E, Glas, M W, Klijn, N F, van der Zanden, M, Bandell, M L, Boxmeer, J C, van Disseldorp, J, Smeenk, J, van Wely, M, Eijkemans, M J C, Torrance, H L, Broekmans, F J M“…The estimated chance of a live birth after 12 months of follow-up was 44.1% in the scratch group compared to 39.3% in the control group (risk difference 4.8%, 95% CI −1.6% to +11.2%). The mean costs were on average €283 (95% CI: −€299 to €810) higher in the scratch group so that the point average ICER was €5846 per additional live birth. …”
Publicado 2021
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926815“…RESULTS: A total of fifty nine articles were identified through several databases search, there were 3 articles removed after duplication screening, 38 articles excluded through title and abstract screening, 8 studies were not included after full text eligibility assessment, thus a total of 10 articles were selected for this systematic review. …”
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926816por Man, Yik Long, Hession, Charlie, Rose, Geoffrey, Wilkins, Bridget, Wrench, David, D'Cruz, David“…Ocular adnexal lymphomas form 1—2% of non-Hodgkin lymphomas and 8% of extranodal lymphomas. Over recent decades the incidence has increased, partly reflecting better diagnostic techniques. …”
Publicado 2021
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926817“…CASE REPORT - CASE DESCRIPTION: A 76-year-old white man developed fever, bony leg pain – which rendered him unable to walk – and frontal headache, within 8 hours of his first zoledronate infusion for osteoporosis. …”
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926818“…Bloods: Hb 101 WCC 5.1 Neutrophils 3.8 Platelets 318 CRP 276 ESR 72 Urate normal. MRI showed a right hip joint effusion, with extensive soft tissue oedema likely secondary to infection. …”
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926819Publicado 2022“…During the pre-vaccine period, the estimated 33% decrease in median IFR over 8 months suggests that treatment for COVID-19 has improved over time. …”
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926820por Vinsonneau, L, Labrosse, J, Porcu-Buisson, G, Chevalier, N, Galey, J, Ahdad, N, Ayel, J P, Rongières, C, Bouet, P E, Mathieu d’Argent, E, Cédrin-Durnerin, I, Pessione, F, Massin, N“…The sample size required was calculated to detect an increase of 5% in the pregnancy loss rate (21–26%), with an alpha risk of 0.5 and a power of 0.8. We calculated that 1126 pregnancies were needed in each group, i.e. 3378 in total. …”
Publicado 2022
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