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926981por Aman, Jurjan, Duijvelaar, Erik, Botros, Liza, Kianzad, Azar, Schippers, Job R, Smeele, Patrick J, Azhang, Sara, Bartelink, Imke H, Bayoumy, Ahmed A, Bet, Pierre M, Boersma, Wim, Bonta, Peter I, Boomars, Karin A T, Bos, Lieuwe D J, van Bragt, Job J M H, Braunstahl, Gert-Jan, Celant, Lucas R, Eger, Katrien A B, Geelhoed, J J Miranda, van Glabbeek, Yurika L E, Grotjohan, Hans P, Hagens, Laura A, Happe, Chris M, Hazes, Boaz D, Heunks, Leo M A, van den Heuvel, Michel, Hoefsloot, Wouter, Hoek, Rianne J A, Hoekstra, Romke, Hofstee, Herman M A, Juffermans, Nicole P, Kemper, E Marleen, Kos, Renate, Kunst, Peter W A, Lammers, Ariana, van der Lee, Ivo, van der Lee, E Laurien, Maitland-van der Zee, Anke-Hilse, Mau Asam, Pearl F M, Mieras, Adinda, Muller, Mirte, Neefjes, Elisabeth C W, Nossent, Esther J, Oswald, Laurien M A, Overbeek, Maria J, Pamplona, Carolina C, Paternotte, Nienke, Pronk, Niels, de Raaf, Michiel A, van Raaij, Bas F M, Reijrink, Merlijn, Schultz, Marcus J, Serpa Neto, Ary, Slob, Elise M A, Smeenk, Frank W J M, Smit, Marry R, Smits, A Josien, Stalenhoef, Janneke E, Tuinman, Pieter R, Vanhove, Arthur L E M, Wessels, Jeroen N, van Wezenbeek, Jessie C C, Vonk Noordegraaf, Anton, de Man, Frances S, Bogaard, Harm J“…Time to discontinuation of ventilation and supplemental oxygen for more than 48 h was not significantly different between the two groups (unadjusted hazard ratio [HR] 0·95 [95% CI 0·76–1·20]). At day 28, 15 (8%) of 197 patients had died in the imatinib group compared with 27 (14%) of 188 patients in the placebo group (unadjusted HR 0·51 [0·27–0·95]). …”
Publicado 2021
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926982por Souza, William M, Amorim, Mariene R, Sesti-Costa, Renata, Coimbra, Lais D, Brunetti, Natalia S, Toledo-Teixeira, Daniel A, de Souza, Gabriela F, Muraro, Stefanie P, Parise, Pierina L, Barbosa, Priscilla P, Bispo-dos-Santos, Karina, Mofatto, Luciana S, Simeoni, Camila L, Claro, Ingra M, Duarte, Adriana S S, Coletti, Thais M, Zangirolami, Audrey B, Costa-Lima, Carolina, Gomes, Arilson B S P, Buscaratti, Lucas I, Sales, Flavia C, Costa, Vitor A, Franco, Lucas A M, Candido, Darlan S, Pybus, Oliver G, de Jesus, Jaqueline G, Silva, Camila A M, Ramundo, Mariana S, Ferreira, Giulia M, Pinho, Mariana C, Souza, Leandro M, Rocha, Esmenia C, Andrade, Pamela S, Crispim, Myuki A E, Maktura, Grazielle C, Manuli, Erika R, Santos, Magnun N N, Camilo, Cecilia C, Angerami, Rodrigo N, Moretti, Maria L, Spilki, Fernando R, Arns, Clarice W, Addas-Carvalho, Marcelo, Benites, Bruno D, Vinolo, Marco A R, Mori, Marcelo A S, Gaburo, Nelson, Dye, Christopher, Marques-Souza, Henrique, Marques, Rafael E, Farias, Alessandro S, Diamond, Michael S, Faria, Nuno R, Sabino, Ester C, Granja, Fabiana, Proença-Módena, Jose Luiz“…FINDINGS: In terms of VNT(50), plasma from individuals previously infected with SARS-CoV-2 had an 8·6 times lower neutralising capacity against the P.1 isolates (median VNT(50) 30 [IQR <20–45] for P.1/28 and 30 [<20–40] for P.1/30) than against the lineage B isolate (260 [160–400]), with a binominal model showing significant reductions in lineage P.1 isolates compared with the lineage B isolate (p≤0·0001). …”
Publicado 2021
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926983por Berg, Stephanie, Kim, Seo-Hyun, Patel, Sonam, Rajakumar, Priya, Elliott, Elizabeth Jane, Schwartz, Candice, Coggan, James, Wozniak, Amy, Zhang, Yanyu, Arain, Saad, Kodali, Abhigna, Singh, Daulath, Odetola, Oluwatobi, Dalal, Hina, Feltman Frank, Rebecca, Kreppel, Diana, Murchie, Ellen, Pax, Laura, Aleem, Ahmed, Guerrettaz, Ryan, Lee, Raymond W., Delgado-Ramos, Glenda, Esmail, Fatema, Moore, Patrick, Qin, Shuai, Torgerson, Nicholas, Watson, Tracie, Barton, Kevin, Hagen, Patrick, Hossain, Nasheed, Katsouli, Anthi, Lowery, Erin M, Larson, Melissa L., Mai, Hanh, Phelan, Katie W., Nand, Sucha, Stiff, Patrick J., Saraf, Santosh L.“…-https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/county-map.html; accessed 8/7/20. [Figure: see text] DISCLOSURES: Arain:Astellas: Other: Spouse is employed. …”
Publicado 2020
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926984por Bonifacio, Massimiliano, Binotto, Gianni, Tiribelli, Mario, Miggiano, Maria Cristina, Trawinska, Malgorzata Monika, Scaffidi, Luigi, Di Bona, Eros, Damiani, Daniela, Velotta, Vanessa, Ceccarelli, Giulia, Pierdomenico, Elisabetta, Loschirico, Mariella, Dubbini, Maria Vittoria, Cordioli, Maddalena, Ruggeri, Marco, Fanin, Renato, Semenzato, Gianpietro, Tacconelli, Evelina, Pizzolo, Giovanni, Krampera, Mauro“…Median time from CML diagnosis was 8 (range 0.1-29.6) years. The majority of patients were in frontline TKI treatment (n=174, 51.3%), and the remaining were in 2(nd)line (n=80, 23.6%), 3(rd)or further line of treatment (n=35, 10.3%), or in TFR (n=50, 14.7%). …”
Publicado 2020
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926985por Xhaard, Alienor, Xhaard, Constance, D'Aveni, Maud, Salvator, Hélène, Chabi-Charvillat, Marie-Laure, Coman, Tereza, Beguin, Yves, Chalandon, Yves, Poire, Xavier, Loschi, Michael, Paillard, Catherine, Bruno, Bénédicte, Ceballos, Patrice, Dalle, Jean-Hugues, Bilger, Karin, Bay, Jacques-Olivier, Robin, Marie, N'guyen-Quoc, Stephanie, Rubio, Marie Thérèse“…Severe COVID-19 patients were more likely to have symptoms at COVID-19 diagnosis (100% vs. 81.8%, p=0.04), especially pneumonia and symptoms other than respiratory or digestive (asthenia, neurological symptoms, myalgia, dysgeusia, skin lesions and arthralgia), and to experience co-infection during the course of the disease (52.4% vs. 21.2%, p= 0.001). …”
Publicado 2020
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926986por Roberti, Maria do Rosario Ferraz, Prudente, Tiago Paiva, Castro, Renato Gomes, Candido, Marcos Antonio, Rodrigues, Roberta Luiza, Candido, Francielle Barreto Machado, Gonçalves, Alexandra Vilela, de Sá, Jaciane Soares, Rabahi, Marcelo Fouad, Arantes, Adriano de Moraes“…After serological screening, 44/70 (62.8%) were considered eligible for CP donation. The reasons for ineligibility were: 17/70 (24.3%) non-reagent IgG, 4/70 (5.7%) with detectable RT-PCR and 5/70 (7.1%) due to reasons in clinical screening. …”
Publicado 2020
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926987por Smith, Wally R, Jaworowski, Benjamin, Johnson, Shirley, Lipato, Thokozeni, Sop, Daniel M“…A total of 219/353 had email surveys sent. Of 63 patients (28.8%) who returned email surveys by June 10, 2020, 35.9% had already managed a “pain attack” at home 4 or more times in the prior 12 months, and 45.5% of these said their bad ER experiences were very or somewhat important in that decision. …”
Publicado 2020
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926988“…RESULTS: Our meta‐analysis identified that bullying programs significantly reduce bullying perpetration (RE: odds ratio [OR] = 1.309; 95% confidence interval [CI]: 1.24–1.38; z = 9.88; p < .001) and bullying victimization (RE: OR = 1.244; 95% CI: 1.19–1.31; z = 8.92; p < .001), under a random effects model of meta‐analysis. …”
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926989por Qiao, Jie, Zhang, Yunshan, Liang, Xiaoyan, Ho, Tuong, Huang, Hong-Yuan, Kim, Sung-Hoon, Goethberg, Marie, Mannaerts, Bernadette, Arce, Joan-Carles“…Nevertheless, compared to the conventional dosing approach, the individualised follitropin delta dosing regimen resulted in on average 2 more oocytes (9.6 ± 5.3 versus 7.6 ± 3.5) in potential low responders as indicated by AMH <15 pmol/l, and on average 3 fewer oocytes (10.1 ± 6.3 versus 13.8 ± 7.5) in potential high responders as indicated by AMH ≥15 pmol/l. …”
Publicado 2021
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926990“…Results: out of 14 cross-sectional studies and one case-control study, 8 studies (10 data sets) provided association data for the meta-analysis. …”
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926991por Yunker, Alexandra G., Alves, Jasmin M., Luo, Shan, Angelo, Brendan, DeFendis, Alexis, Pickering, Trevor A., Monterosso, John R., Page, Kathleen A.“…For each study visit, participants arrived at the Dornsife Cognitive Neuroimaging Center of University of Southern California at approximately 8:00 am after a 12-hour overnight fast. Blood was sampled at baseline and 10, 35, and 120 minutes after participants received a drink containing sucrose, sucralose, or water to measure plasma glucose, insulin, glucagon-like peptide((7-36)), acyl-ghrelin, total peptide YY, and leptin. …”
Publicado 2021
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926992por Weber, Griffin M, Zhang, Harrison G, L'Yi, Sehi, Bonzel, Clara-Lea, Hong, Chuan, Avillach, Paul, Gutiérrez-Sacristán, Alba, Palmer, Nathan P, Tan, Amelia Li Min, Wang, Xuan, Yuan, William, Gehlenborg, Nils, Alloni, Anna, Amendola, Danilo F, Bellasi, Antonio, Bellazzi, Riccardo, Beraghi, Michele, Bucalo, Mauro, Chiovato, Luca, Cho, Kelly, Dagliati, Arianna, Estiri, Hossein, Follett, Robert W, García Barrio, Noelia, Hanauer, David A, Henderson, Darren W, Ho, Yuk-Lam, Holmes, John H, Hutch, Meghan R, Kavuluru, Ramakanth, Kirchoff, Katie, Klann, Jeffrey G, Krishnamurthy, Ashok K, Le, Trang T, Liu, Molei, Loh, Ne Hooi Will, Lozano-Zahonero, Sara, Luo, Yuan, Maidlow, Sarah, Makoudjou, Adeline, Malovini, Alberto, Martins, Marcelo Roberto, Moal, Bertrand, Morris, Michele, Mowery, Danielle L, Murphy, Shawn N, Neuraz, Antoine, Ngiam, Kee Yuan, Okoshi, Marina P, Omenn, Gilbert S, Patel, Lav P, Pedrera Jiménez, Miguel, Prudente, Robson A, Samayamuthu, Malarkodi Jebathilagam, Sanz Vidorreta, Fernando J, Schriver, Emily R, Schubert, Petra, Serrano Balazote, Pablo, Tan, Byorn WL, Tanni, Suzana E, Tibollo, Valentina, Visweswaran, Shyam, Wagholikar, Kavishwar B, Xia, Zongqi, Zöller, Daniela, Kohane, Isaac S, Cai, Tianxi, South, Andrew M, Brat, Gabriel A“…Patients hospitalized in the second wave had a 9.9% reduction in the risk of severe COVID-19 compared to patients hospitalized in the first wave (95% CI 8.5%-11.3%). Demographic subgroup analyses indicated that patients aged 26 to 49 years and 50 to 69 years; male and female patients; and black patients had significantly lower risk for severe disease in the second wave than in the first wave. …”
Publicado 2021
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926993por Declercq, Jozefien, Van Damme, Karel F A, De Leeuw, Elisabeth, Maes, Bastiaan, Bosteels, Cedric, Tavernier, Simon J, De Buyser, Stefanie, Colman, Roos, Hites, Maya, Verschelden, Gil, Fivez, Tom, Moerman, Filip, Demedts, Ingel K, Dauby, Nicolas, De Schryver, Nicolas, Govaerts, Elke, Vandecasteele, Stefaan J, Van Laethem, Johan, Anguille, Sebastien, van der Hilst, Jeroen, Misset, Benoit, Slabbynck, Hans, Wittebole, Xavier, Liénart, Fabienne, Legrand, Catherine, Buyse, Marc, Stevens, Dieter, Bauters, Fre, Seys, Leen J M, Aegerter, Helena, Smole, Ursula, Bosteels, Victor, Hoste, Levi, Naesens, Leslie, Haerynck, Filomeen, Vandekerckhove, Linos, Depuydt, Pieter, van Braeckel, Eva, Rottey, Sylvie, Peene, Isabelle, Van Der Straeten, Catherine, Hulstaert, Frank, Lambrecht, Bart N“…In a second randomisation step, patients were allocated to receive a single dose of siltuximab (11 mg/kg) intravenously, or a single dose of tocilizumab (8 mg/kg) intravenously, or to receive no IL-6 blockade (1:1:1). …”
Publicado 2021
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926994por Cantrell, William, Swinehart, Steven, Johnson, Carrie, Strnad, Greg, Obuchowski, Nancy, Cox, Charles, Spindler, Kurt“…The infection rate for the entire MOON cohort is 0.8% (allograft and autograft), the BTB autograft is 0.3%, and the hamstring autograft is1.3%. …”
Publicado 2021
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926995por Barnds, Brandon, Witt, Atlee, Orahovats, Alexanda, Schlegel, Theodore, Hunt, Kenneth“…Patients who completed all or some of their PROs completed them before their appointment 56.02% of the time (n = 2773), within an hour of their appointment 35.49% of the time (n = 1757), and after their appointment 8.48% of the time (n = 420) (see Figure 1). After separating PRO completion rates by month, we noticed a shift in compliance and patient response patterns before and during the coronavirus pandemic. …”
Publicado 2021
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926996por Arlet, J.B., Lionnet, F., Khimoud, D., Joseph, L., De Montalembert, M., Garou, A., Cannas, G., Cougoul, P., Guitton, C., Holvoet, L., Odièvre, M.H., Cheminet, G., Bartolucci, P., Santin, A., Bernit, E., De Luna, G.“…Chez les adultes, les patients âgés de plus de 40 ans (n = 59) présentaient un risque 8,3 fois plus élevé [IC 95 % 2,6–31,2] de décès ou d’intubation par rapport aux patients âgés de 20 à 40 ans (n = 153) (P < 0,001). …”
Publicado 2021
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926997por Jerbi, Z., Arfaoui, B., Gueddich, N.N., Boussetta, N., Ajili, F., Ben Abdelhafidh, N., Louzir, B.“…La symptomatologie était dominée par : la fièvre dans 49,2 % des cas, myalgies et arthralgies dans 60,3 % des cas et l’asthénie dans 77,8 % des cas. La saturation moyenne à l’air ambiant à l’admission était de 90 ± 3,17 % avec des extrêmes entre 81 et 99 %. …”
Publicado 2021
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926998por Fogel, O., Beretta, M., Planchais, C., Bruneau, T., Goncalves, P., Avouac, J., Berenbaum, F., Sellam, J., Deprouw, C., Fautrel, B., Morel, J., Parfait, B., Di Santo, J., Behillil, S., Van Der Werf, S., Péré, H., Mouquet, H., Miceli Richard, C.“…Les réponses immunes ont été analysées selon 6 groupes de traitement : méthotrexate (MTX)/salazopyrine (SLZ) monothérapie (n = 17/2) ; anti-TNF monothérapie (n = 24), anti-TNF + MTX (n = 23) ; rituximab (RTX) (n = 11) ; traitements ciblant la voie IL17/23 (n = 8) ; autres (n = 11). Les visites étaient effectuées à 1 mois (29 ± 13 jours ; n = 18), 3 mois (110 ± 23 jours ; n = 67), 6 mois (231 ± 35 jours ; n = 48) et 12 mois (368 ± 19 jours ; n = 19) après l’infection. …”
Publicado 2021
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926999por Mariette, X., Lawson-Tovey, S., Hachulla, E., Veillard, E., Trefond, L., Soubrier, M., Roux, N., Brocq, O., Durez, P., Goulenok, T., Gossec, L., Strakova, E., Burmester, G.R., Kübra, Y.G., Gomez, P.J.A., Zepa, J., Hyrich, K., Cunha, M.M., Mosca, M., Cornalba, M., Mateus, E., Carmona, L., Rodrigues, A., Raffeiner, B., Conway, R., Strangfeld, A., Bijlsma, H., McInnes, I.B., Machado, P.“…La plupart des patients ont reçu le vaccin Pfizer/BioNTech (70 %), 17 % AstraZeneca/Oxford et 8 % Moderna. Une infection COVID post-vaccination a été signalée dans 0,7 à 1,1 % des cas, selon le statut vaccinal (entièrement/partiellement vacciné) et le groupe RMD. …”
Publicado 2021
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927000por Cadiou, S., Ardois, S., Lamer, F., Perdriger, A., Albert, J.D., Berthoud, O., Lescoat, A., Robin, F., Guggenbuhl, P.“…La première patiente, âgée de 70 ans et atteinte d’une PPR en rémission sous prednisone 8 mg/j, a développé une altération de l’état général rapide 10 jours après sa vaccination par ChAdOx1 (AstraZeneca). …”
Publicado 2021
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