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  1. 927001
    “…La réponse cellulaire T contre les peptides de la protéine Spike a été réalisée en détectant le marquage intracellulaire du TNF, de l’IFNg, de l’IL2, sur les lymphocytes T CD4 et CD8 activés. RÉSULTATS: Vingt-huit contrôles et 57 patients atteints de MAI ont été inclus ; 24 patients dans le groupe rituximab et 33 dans l’autre groupe autre IS. …”
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    Le traitement par rituximab diminue la réponse humorale, mais pas la réponse cellulaire, après vaccination anti-SARS-CoV-2 chez des patients atteints de maladie auto-immune
  2. 927002
    “…RESULTS: Central line-associated blood stream infections (CLABSI), catheter-associated urinary tract infections (CAUTI), and methicillin-resistant Staphylococcus aureus (MRSA) bacteremia increased as COVID-19 burden increased (P ≤ 0.001 for all), with 60% (95% CI, 23 to 108%) more CLABSI, 43% (95% CI, 8 to 90%) more CAUTI, and 44% (95% CI, 10 to 88%) more cases of MRSA bacteremia than expected over 7 months based on predicted HAIs had there not been COVID-19 cases. …”
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    171. The Impact of COVID-19 on Healthcare-Associated Infections
  3. 927003
    por van Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola, Cooper-Knock, Johnathan, Smith, Bradley N., Gromicho, Marta, Chandran, Siddharthan, Pal, Suvankar, Morrison, Karen E., Shaw, Pamela J., Hardy, John, Orrell, Richard W., Sendtner, Michael, Meyer, Thomas, Başak, Nazli, van der Kooi, Anneke J., Ratti, Antonia, Fogh, Isabella, Gellera, Cinzia, Lauria, Giuseppe, Corti, Stefania, Cereda, Cristina, Sproviero, Daisy, D’Alfonso, Sandra, Sorarù, Gianni, Siciliano, Gabriele, Filosto, Massimiliano, Padovani, Alessandro, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Brunetti, Maura, Canosa, Antonio, Grassano, Maurizio, Beghi, Ettore, Pupillo, Elisabetta, Logroscino, Giancarlo, Nefussy, Beatrice, Osmanovic, Alma, Nordin, Angelica, Lerner, Yossef, Zabari, Michal, Gotkine, Marc, Baloh, Robert H., Bell, Shaughn, Vourc’h, Patrick, Corcia, Philippe, Couratier, Philippe, Millecamps, Stéphanie, Meininger, Vincent, Salachas, François, Mora Pardina, Jesus S., Assialioui, Abdelilah, Rojas-García, Ricardo, Dion, Patrick A., Ross, Jay P., Ludolph, Albert C., Weishaupt, Jochen H., Brenner, David, Freischmidt, Axel, Bensimon, Gilbert, Brice, Alexis, Durr, Alexandra, Payan, Christine A. M., Saker-Delye, Safa, Wood, Nicholas W., Topp, Simon, Rademakers, Rosa, Tittmann, Lukas, Lieb, Wolfgang, Franke, Andre, Ripke, Stephan, Braun, Alice, Kraft, Julia, Whiteman, David C., Olsen, Catherine M., Uitterlinden, Andre G., Hofman, Albert, Rietschel, Marcella, Cichon, Sven, Nöthen, Markus M., Amouyel, Philippe, Traynor, Bryan J., Singleton, Andrew B., Mitne Neto, Miguel, Cauchi, Ruben J., Ophoff, Roel A., Wiedau-Pazos, Martina, Lomen-Hoerth, Catherine, van Deerlin, Vivianna M., Grosskreutz, Julian, Roediger, Annekathrin, Gaur, Nayana, Jörk, Alexander, Barthel, Tabea, Theele, Erik, Ilse, Benjamin, Stubendorff, Beatrice, Witte, Otto W., Steinbach, Robert, Hübner, Christian A., Graff, Caroline, Brylev, Lev, Fominykh, Vera, Demeshonok, Vera, Ataulina, Anastasia, Rogelj, Boris, Koritnik, Blaž, Zidar, Janez, Ravnik-Glavač, Metka, Glavač, Damjan, Stević, Zorica, Drory, Vivian, Povedano, Monica, Blair, Ian P., Kiernan, Matthew C., Benyamin, Beben, Henderson, Robert D., Furlong, Sarah, Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Ngo, Shyuan T., Nicholson, Garth A., Pamphlett, Roger, Rowe, Dominic B., Steyn, Frederik J., Williams, Kelly L., Mather, Karen A., Sachdev, Perminder S., Henders, Anjali K., Wallace, Leanne, de Carvalho, Mamede, Pinto, Susana, Petri, Susanne, Weber, Markus, Rouleau, Guy A., Silani, Vincenzo, Curtis, Charles J., Breen, Gerome, Glass, Jonathan D., Brown, Robert H., Landers, John E., Shaw, Christopher E., Andersen, Peter M., Groen, Ewout J. N., van Es, Michael A., Pasterkamp, R. Jeroen, Fan, Dongsheng, Garton, Fleur C., McRae, Allan F., Davey Smith, George, Gaunt, Tom R., Eberle, Michael A., Mill, Jonathan, McLaughlin, Russell L., Hardiman, Orla, Kenna, Kevin P., Wray, Naomi R., Tsai, Ellen, Runz, Heiko, Franke, Lude, Al-Chalabi, Ammar, Van Damme, Philip, van den Berg, Leonard H., Veldink, Jan H.
    Publicado 2021
    “…We conducted a cross-ancestry genome-wide association study (GWAS) including 29,612 patients with ALS and 122,656 controls, which identified 15 risk loci. When combined with 8,953 individuals with whole-genome sequencing (6,538 patients, 2,415 controls) and a large cortex-derived expression quantitative trait locus (eQTL) dataset (MetaBrain), analyses revealed locus-specific genetic architectures in which we prioritized genes either through rare variants, short tandem repeats or regulatory effects. …”
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    Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
  4. 927004
    “…HMs included aggressive B-cell lymphomas (n=74, 31%), indolent B-cell lymphomas (n=52, 22%), chronic lymphocytic leukemia (CLL, n=30, 13%), other lymphomas (n-19, 8%), plasma cell neoplasms (n=43, 18%), and myeloid cancers (n=21, 9%); 140 pts (59%) received BNT162b2/Pfizer, 74 (31%) mRNA-1273/Moderna, and 23 (10%) Ad26.COV2.S/J&J vaccines (2 pts had undetermined vaccine type). …”
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    Factors Associated with Seroconversion after COVID-19 Vaccination in Patients with Hematologic Malignancies
  5. 927005
    “…T cell responses were measured on 38/65 vaccinated patients (32 allo-HCT/6 auto-HCT) with a median of 3 (0.17-31) and 2 years (1.25-8) post allo- and auto-HCT respectively, and 19 healthy, unexposed vaccinees. …”
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    Humoral and T Cell Immune Responses to Sars-Cov-2 Vaccination in Hematopoietic Cell Transplant Recipients
  6. 927006
    “…Our model found that peri-vaccination CD4 count greater than 200 cells/mm3 was a significant predictor of positive SARS-CoV-2 IgG serologies in this population (OR 2.14, 97.5% CI = 0.7 to 3.8, p= 0.005). Transplant to vaccine interval, total IgG levels, GVHD status, and immunosuppressive therapies were not significant predictors of serologic response. …”
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    Incidence and Predictors of Sars-Cov-2 Antibody Responses Following COVID-19 Vaccination in Allogeneic Stem Cell Transplant Recipients
  7. 927007
    “…A positive response was defined as > 0.8 U/mL. Upper and lower limits of quantification were 0,4 U/mL and 250 U/mL respectively. …”
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    Serologic Responses Following Sars-Cov-2 Vaccination and Factors Influencing It in Patients with Hematological Malignant and Non-Malignant Diseases - a Prospective Multicentric Study
  8. 927008
    “…The majority of pts (67.3%) had a myeloid malignancy (MDS/CMML 29.5%, AML 14.8%, myelofibrosis 16.4%, CML 6.6%), followed by chronic lymphocytic leukemia (16.4%), and others (6.6%). …”
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    COVID Vaccine Antibody Responses in Patients with Hematologic Malignancies in a Myeloid Enriched Cohort: A Better Antibody Response in Patients with Myeloid Malignancies Than B-Cell Malignancies
  9. 927009
    “…SEARCH METHODS: We searched the Cochrane Infectious Diseases Group Specialized Register; CENTRAL; MEDLINE; and five other databases for records from 1 January 2000 to 8 November 2021, on the basis that ITN programmes did not begin to be implemented as policy before the year 2000. …”
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    Indoor residual spraying for preventing malaria in communities using insecticide‐treated nets
  10. 927010
    “…Its prevalence ranges from 1% to 8% in different cohorts. The main clinical feature of anti-SAE-1-positive disease tends to be a widespread cutaneous involvement which is typically pruritic, either amyopathic or associated with mild muscle involvement. …”
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    P04 Primary mediastinal large B-cell lymphoma in a Caucasian female with anti-SAE-1 positive dermatomyositis
  11. 927011
    por Dhana, Ashar, Hamada, Yohhei, Kengne, Andre P, Kerkhoff, Andrew D, Rangaka, Molebogeng X, Kredo, Tamara, Baddeley, Annabel, Miller, Cecily, Singh, Satvinder, Hanifa, Yasmeen, Grant, Alison D, Fielding, Katherine, Affolabi, Dissou, Merle, Corinne S, Wachinou, Ablo Prudence, Yoon, Christina, Cattamanchi, Adithya, Hoffmann, Christopher J, Martinson, Neil, Mbu, Eyongetah Tabenyang, Sander, Melissa S, Balcha, Taye T, Skogmar, Sten, Reeve, Byron W P, Theron, Grant, Ndlangalavu, Gcobisa, Modi, Surbhi, Cavanaugh, Joseph, Swindells, Susan, Chaisson, Richard E, Ahmad Khan, Faiz, Howard, Andrea A, Wood, Robin, Thit, Swe Swe, Kyi, Mar Mar, Hanson, Josh, Drain, Paul K, Shapiro, Adrienne E, Kufa, Tendesayi, Churchyard, Gavin, Nguyen, Duc T, Graviss, Edward A, Bjerrum, Stephanie, Johansen, Isik S, Gersh, Jill K, Horne, David J, LaCourse, Sylvia M, Al-Darraji, Haider Abdulrazzaq Abed, Kamarulzaman, Adeeba, Kempker, Russell R, Tukvadze, Nestani, Barr, David A, Meintjes, Graeme, Maartens, Gary
    Publicado 2022
    “…Among outpatients not on ART (11 160 [71·8%] of 15 541 outpatients), W4SS sensitivity was 85% (76–91) and specificity was 37% (25–51). …”
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    Tuberculosis screening among ambulatory people living with HIV: a systematic review and individual participant data meta-analysis
  12. 927012
    “…We did not detect a clear benefit or harm of distress tolerance training on quit rates compared with intensity‐matched smoking cessation treatment (RR 0.87, 95% CI 0.26 to 2.98; 1 study, 69 participants; low‐certainty evidence) or less intensive smoking cessation treatment (RR 1.63, 95% CI 0.33 to 8.08; 1 study, 49 participants; low‐certainty evidence). …”
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    Mindfulness for smoking cessation
  13. 927013
    “…Only 12 studies analysing 8 different populations (N = 4300) could be used in the data synthesis. …”
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    Adult/child ratio and group size in early childhood education or care to promote the development of children aged 0–5 years: A systematic review
  14. 927014
    “…In this group, 22 of the 54 women (41%) allocated to management based on HyFoSy and 25 of 51 women (49%) allocated to management based on HSG had an ongoing pregnancy leading to live birth (Difference −8%; 95% CI: −27% to 10%). In total, clinical management based on the results of HyFoSy was estimated to lead to a live birth in 474 of 1026 women (46%) versus 486 of 1026 (47%) for management based on HSG (Difference −1.2%; 95% CI: −3.4% to 1.5%). …”
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    Can hysterosalpingo-foam sonography replace hysterosalpingography as first-choice tubal patency test? A randomized non-inferiority trial
  15. 927015
    por Munro, Alasdair P S, Feng, Shuo, Janani, Leila, Cornelius, Victoria, Aley, Parvinder K, Babbage, Gavin, Baxter, David, Bula, Marcin, Cathie, Katrina, Chatterjee, Krishna, Dodd, Kate, Enever, Yvanne, Qureshi, Ehsaan, Goodman, Anna L, Green, Christopher A, Harndahl, Linda, Haughney, John, Hicks, Alexander, van der Klaauw, Agatha A, Kanji, Nasir, Libri, Vincenzo, Llewelyn, Martin J, McGregor, Alastair C, Maallah, Mina, Minassian, Angela M, Moore, Patrick, Mughal, Mehmood, Mujadidi, Yama F, Holliday, Kyra, Osanlou, Orod, Osanlou, Rostam, Owens, Daniel R, Pacurar, Mihaela, Palfreeman, Adrian, Pan, Daniel, Rampling, Tommy, Regan, Karen, Saich, Stephen, Bawa, Tanveer, Saralaya, Dinesh, Sharma, Sunil, Sheridan, Ray, Thomson, Emma C, Todd, Shirley, Twelves, Chris, Read, Robert C, Charlton, Sue, Hallis, Bassam, Ramsay, Mary, Andrews, Nick, Lambe, Teresa, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D, Liu, Xinxue, Faust, Saul N
    Publicado 2022
    “…The median interval between the third and fourth doses was 208·5 days (IQR 203·3–214·8). Pain was the most common local solicited adverse event and fatigue was the most common systemic solicited adverse event after BNT162b2 or mRNA-1273 booster doses. …”
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    Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial
  16. 927016
    “…Dix patients (77 %) ont eu un traitement de première ligne, 8 (80 %) ont été traités par corticoides et 2 par colchicine. …”
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    Vascularites à IgA survenues dans les suites d’une infection à SARS-CoV-2 et post vaccination contre la COVID 19 : une série de 19 patients
  17. 927017
    “…Post hoc comparison showed that (Bonferroni) anger group (M = 8.94, SD = 4.77) was higher than sadness group (M = 6.32, SD = 2.40, P = 0.005, Cohen'sd = 0.69) and neutral emotion group (M = 4.56, SD = 2.23, P < 0.001, Cohen'sd = 1.18). …”
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    THE IMPACT OF CHINESE ENTREPRENEURS' EMOTIONAL LABOR AND WORK PRESSURE ON EXPORT PROFITABILITY: EVIDENCE FROM CHINA
  18. 927018
    “…METHODS: A total of 30 participants were enrolled into this study [ACL-r n: 15, age(yrs): 38.8±13.9, Ht(cm): 173.4±10.0, Wt(kg): 77.9±17.5; ACLR: n: 15, age(yrs): 25.60±1.7, Ht(cm): 173.5±10.3, Wt(kg): 75.4±15.6]. …”
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    Paper 84: Differences in Metrics of Knee Joint Loading Between Individuals Following a Primary Anterior Cruciate Ligament Repair (ACL-R) Surgery Versus Those Who Underwent a Standard ACL Reconstruction with a Patella Bone-Tendon-Bone Autograft (ACLR)
  19. 927019
    “…Rabbits were then randomly divided into 4 groups (N=8/group): MFx alone, MFx+FIS, MFx+BMAC and MFx+FIS+BMAC. …”
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    Paper 40: Improved Cartilage Healing with Microfracture Augmented with Fisetin & Bone Marrow Aspirate Concentrate in Acute Osteochondral Defect
  20. 927020
    “…Thus, we believe specific T-Cell subsets (CD4, CD8) may be more reflective of the healthspan and warrant further investigation. …”
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    Poster 125: Determining Biological Age and Prolonging the Healthspan by Targeting Senescence
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