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  1. 1821
    por Iwahashi, Hideo
    Publicado 2009
    “…Electrospray inonization mass (ESI-MS) spectra of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) and 2'-deoxyguanosine (dG) were measured in order to know whether or not 8-oxodG forms a tetrameric structure as 2'-deoxyguanosine forms in teromeres. …”
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    8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine
  2. 1822
    “…BACKGROUND: We previously demonstrated remarkable differences in the expression of IL-8/CXCL8 in aortic tissues and vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) compared to VSMC from normotensive Wistar-Kyoto rats (WKY). …”
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    IL-8/CXCL8 Upregulates 12-Lipoxygenase Expression in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats
  3. 1823
    “…Here, we report the crystal structure of the TEM8 extracellular vWA domain at 1.7 Å resolution. …”
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    The Structure of Tumor Endothelial Marker 8 (TEM8) Extracellular Domain and Implications for Its Receptor Function for Recognizing Anthrax Toxin
  4. 1824
    “…The major product of oxidative base damage is 8-oxo-7,8-dihydro-2′-deoxyguanine (8odG). The coding potential of this lesion is modulated by its glycosidic torsion angle that controls whether its Watson-Crick or Hoogsteen edge is utilized for base pairing. …”
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    Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active site
  5. 1825
    “…The strained micronetworks were exposed to active matrix metalloproteinase 8 (MMP-8) and relative degradation rates for loaded and unloaded fibrils were tracked simultaneously using label-free differential interference contrast (DIC) imaging. …”
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    Mechanical Strain Stabilizes Reconstituted Collagen Fibrils against Enzymatic Degradation by Mammalian Collagenase Matrix Metalloproteinase 8 (MMP-8)
  6. 1826
    “…In the title mol­ecule, C(24)H(22)O(8), the mean planes of the two coumarin units are inclined to each other at a dihedral angle of 79.93 (3)°. …”
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    7,7′,8,8′-Tetra­meth­oxy-4,4′-dimethyl-3,5′-bichromene-2,2′-dione
  7. 1827
    “…The title compound, C(14)H(6)O(7)·C(10)H(8)N(2), has been hydro­thermally synthesized. Structural ananlysis indicates that the crystals are produced by cocrystallization of naphthalene-1,4,5,8-tetra­carboxylic acid 1,8-anhydride and 4,4′-bipyridine (bpy) mol­ecules. …”
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    Naphthalene-1,4,5,8-tetra­carboxylic acid 1,8-anhydride–4,4′-bipyridine (1/1)
  8. 1828
    “…The title compound, K(0.8)Ca(9.8)Fe(0.2)(PO(4))(7) (potassium deca­calcium iron hepta­phosphate), belongs to the whitlockite family. …”
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    Rietveld refinement of whitlockite-related K(0.8)Ca(9.8)Fe(0.2)(PO(4))(7)
  9. 1829
    “…We earlier identified OSBP-related protein 8 (ORP8) as an endoplasmic reticulum oxysterol-binding protein implicated in cellular lipid homeostasis. …”
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    OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62
  10. 1830
    “…Using data from four disease-affected brain regions (Brodmann's Area 9, hippocampus, inferior parietal lobule, and the superior and middle temporal gyri), we found that the RNA adduct 8-hydroxyguanine (8-OHG) decreased, while 8-hydroxyadenine (8-OHA) increased in AD. …”
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    RNA Oxidation Adducts 8-OHG and 8-OHA Change with Aβ(42) Levels in Late-Stage Alzheimer's Disease
  11. 1831
    “…The contribution of innate immunity to immunosurveillance of the oncogenic Human Herpes Virus 8 (HHV8) has not been studied in depth. We investigated NK cell phenotype and function in 70 HHV8-infected subjects, either asymptomatic carriers or having developed Kaposi's sarcoma (KS). …”
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    Human Herpesvirus 8 (HHV8) Sequentially Shapes the NK Cell Repertoire during the Course of Asymptomatic Infection and Kaposi Sarcoma
  12. 1832
    “…The zinc (Zn(++)) transporter ZnT8 plays a crucial role in zinc homeostasis. It’s been reported that an acute decrease in ZnT8 levels impairs β cell function and Zn(++) homeostasis, which contribute to the pathophysiology of diabetes mellitus (DM). …”
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    Zinc Transporter 8 (ZnT8) Expression Is Reduced by Ischemic Insults: A Potential Therapeutic Target to Prevent Ischemic Retinopathy
  13. 1833
    “…We consistently found that adult OT-I CD8 expansion was reduced in aged recipient mice, and this correlated with numeric, phenotypic, and functional defects selectively affecting CD8α+ dendritic cells (DC). …”
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    Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium
  14. 1834
    “…METHODS: Serum creatinine, cystatin C, IL-6, and IL-8 and urine IL-18, NGAL, IL-6, and IL-8 were measured before and within 24 hours after liver transplantation in 40 patients. …”
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    Urine IL-18, NGAL, IL-8 and serum IL-8 are biomarkers of acute kidney injury following liver transplantation
  15. 1835
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    8β-Eth­oxy­eremophil-3,7(11)-diene-8α,12;6α,15-diolide
  16. 1836
    “…The crystal structure of smHDAC8 shows that this enzyme adopts a canonical α/β HDAC fold, with specific solvent exposed loops corresponding to insertions in the schistosome HDAC8 sequence. …”
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    Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni
  17. 1837
    por SARLIS, Nicholas V.
    Publicado 2013
    “…This disturbance was actually followed by an M(w)5.8 earthquake on 8 January 2013 in North-Eastern Aegean Sea. …”
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    On the recent seismic activity in North-Eastern Aegean Sea including the M(w)5.8 earthquake on 8 January 2013
  18. 1838
    “…In this article we determined the effects of VDR expression on CD8(+) T cells. RESULTS: VDR KO CD8(+) T cells, but not WT CD8(+) T cells, induced colitis in Rag KO recipients. …”
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    Vitamin D receptor expression controls proliferation of naïve CD8(+) T cells and development of CD8 mediated gastrointestinal inflammation
  19. 1839
    “…OBJECTIVES: Matrix metalloproteinase-8 (MMP-8) promotes lung fibrotic responses to bleomycin in mice. …”
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    Mononuclear Phagocytes and Airway Epithelial Cells: Novel Sources of Matrix Metalloproteinase-8 (MMP-8) in Patients with Idiopathic Pulmonary Fibrosis
  20. 1840
    “…[Image: see text] One of the most common lesions induced by oxidative DNA damage is 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG). …”
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    Mutagenic Potential of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Bypass Catalyzed by Human Y-Family DNA Polymerases
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