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  1. 1861
    “…Then, major histocompatibility complex class I-restricted CD8(+) T-cell epitopes were selected based on their immunogenicity. …”
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    Designing of CD8(+) and CD8(+)-overlapped CD4(+) epitope vaccine by targeting late and early proteins of human papillomavirus
  2. 1862
    por Gasparri, Paolo, Roncati, Luca
    Publicado 2019
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    Paired Box Gene 8 (Pax8) Is also an Immunomarker of B-Cell Lineage Which Can Be Source of Diagnostic Pitfalls
  3. 1863
    “…TLR8 is an endosomal sensor of RNA degradation products in human phagocytes, and is involved in the recognition of viral and bacterial pathogens. …”
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    Human Toll-like Receptor 8 (TLR8) Is an Important Sensor of Pyogenic Bacteria, and Is Attenuated by Cell Surface TLR Signaling
  4. 1864
    “…Interleukin-8 (IL-8) is an inflammatory cytokine that plays an important role in the inflammatory response through the activation of neutrophil cells. …”
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    Interleukin-8 (IL-8) Expression in the Olive Flounder (Paralichthys olivaceus) against Viral Hemorrhagic Septicemia Virus (VHSV) Challenge
  5. 1865
    “…Here, we show that constitutive transgenic CD8 expression resulted in enhanced differentiation of innate memory-like CD8(+) thymocytes in both a cell-intrinsic and cell-extrinsic manner, the latter being accomplished by an increase in the IL-4–producing iNKT2 subset. …”
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    Constitutive CD8 expression drives innate CD8(+) T-cell differentiation via induction of iNKT2 cells
  6. 1866
    “…In the present study, we investigated whether tooth loss early in life affects the hippocampal ultrastructure in senescence-accelerated mouse prone 8 (SAMP8) mice, using transmission electron microscopy. …”
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    Tooth loss early in life induces hippocampal morphology remodeling in senescence-accelerated mouse prone 8 (SAMP8) mice
  7. 1867
    “…Mechanistically, MCM8IP stimulates the helicase activity of MCM8-9. …”
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    MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage
  8. 1868
    “…Leucobryns represent the first 9,10-phenanthrenequinone dimers, the monomers of which are linked through their C-8 atoms. Leucobryns B–E contain an uncommon C(10) monoterpenoid side chain, in which isoprenoid units are joined by 3,4 linkages. …”
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    Pigments of the Moss Paraleucobryum longifolium: Isolation and Structure Elucidation of Prenyl-Substituted 8,8′-Linked 9,10-Phenanthrenequinone Dimers
  9. 1869
    “…The Human T-cell leukemia virus type 1 (HTLV-1) orf I-encoded accessory protein p8 is cleaved from its precursor p12, and both proteins contribute to viral persistence. p8 induces cellular protrusions, which are thought to facilitate transfer of p8 to target cells and virus transmission. …”
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    Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8
  10. 1870
    “…Here, we analyze certain genomic characteristics of SARS-CoV-2 accessory protein ORF8 and predict its protein features. We have further reviewed current available literature regarding its function and comparatively evaluated these and other features of ORF8 and ORF8ab, its homolog from SARS-CoV. …”
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    SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence
  11. 1871
    “…Cyclin-dependent kinase 8 (CDK8) is a member of the CDK/Cyclin module of the mediator complex. …”
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    Pathogenesis of CDK8-associated disorder: two patients with novel CDK8 variants and in vitro and in vivo functional analyses of the variants
  12. 1872
    “…We have previously shown that volume-regulated anion channels, containing the subunits LRRC8A and LRRC8D, promote the uptake of cisplatin and carboplatin in BRCA1-proficient cell lines. …”
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    Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
  13. 1873
    “…The most frequent DNA lesion resulting from an oxidative stress is 7,8-dihydro-8-oxoguanine (8-oxoG). 8-oxoG is a premutagenic base modification due to its capacity to pair with adenine. …”
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    Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?
  14. 1874
    “…Previous studies reported that CDK8 module predominantly acts as a transcriptional repressor in eukaryotic cells by reversibly associating with core Mediator. …”
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    Signal Integration by Cyclin-Dependent Kinase 8 (CDK8) Module and Other Mediator Subunits in Biotic and Abiotic Stress Responses
  15. 1875
    “…PRINCIPAL MEASUREMENTS: three level categorical scale is broken down into low adherence (score of <6), medium adherence (score of 6 to <8) and high adherence (score of 8). To validate the questionnaire, we measured internal consistency through Cronbach's α, confirmed construct validity through an exploratory principal component analysis and assessed test–retest reliability. …”
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    Validation and psychometric properties of the 8-item Morisky Medication Adherence Scale (MMAS-8) in type 2 diabetes patients in Spain
  16. 1876
    “…RESULTS: We perform a survey of ribosome profiling data and reveal that many pri-miRNAs exhibit ribosome translation marks. Focusing on miR-8, we show that pri-miR-8 can produce a miPEP-8. …”
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    Drosophila primary microRNA-8 encodes a microRNA-encoded peptide acting in parallel of miR-8
  17. 1877
    “…8-Hydroxyguanine (8-oxoG) is the most common oxidative DNA lesion and unrepaired 8-oxoG is associated with DNA fragmentation in sperm. …”
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    Dysregulation of the Acrosome Formation Network by 8-oxoguanine (8-oxoG) in Infertile Sperm: A Case Report with Advanced Techniques
  18. 1878
    “…The human zinc transporter ZnT8 (SLC30A8) is expressed primarily in pancreatic β-cells and plays a key function in maintaining the concentration of blood glucose through its role in insulin storage, maturation and secretion. …”
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    Structure/Function Analysis of human ZnT8 (SLC30A8): A Diabetes Risk Factor and Zinc Transporter
  19. 1879
    “…We confirmed 1699 DEGs between D10 CD8(+) versus D10 CD8(−) groups and 1784 DEGs between D28 CD8(+) versus D28 CD8(−) groups; 646 upregulated and 561 downregulated DEGs were common. …”
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    Comprehensive Transcriptomic Comparison between Porcine CD8(−) and CD8(+) Gamma Delta T Cells Revealed Distinct Immune Phenotype
  20. 1880
    “…However, the complete functional spectrum of S100A8/A9 at the intracellular level is far from being understood. …”
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    Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors
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