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1881NMR resonance assignments of the PR-10 allergens Act c 8 and Act d 8 from golden and green kiwifruit“…In this work we assigned backbone and side chain (1)H, (13)C and (15)N chemical shifts of the 17 kDa PR-10 allergens Act c 8.0101 and Act d 8.0101 from golden (Actinidia chinesis) and green (Actinidia deliciosa) kiwifruit by solution NMR spectroscopy. …”
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1882por Namjoo, Shamsedin, Mirzaei, Masoud, Foroughan, Mahshid, Ghaedamini Harouni, Gholamreza“…Background: The current study aimed to evaluate the psychometric properties of the Persian version of the 8-item Short-Form Health Survey (SF-8). For this purpose, we examined a large sample of the older adult in two different groups with and without diabetes using the YazdHealth Study (YaHS) data. …”
Publicado 2021
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1883“…Zeolite imidazolate framework-8 (ZIF8) represents a class of highly porous materials with a very high surface area, large pore volume, thermal stability, and biocompatibility. …”
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1884por Hollomon, Jeffrey M., Liu, Zhongle, Rusin, Scott F., Jenkins, Nicole P., Smith, Allia K., Koeppen, Katja, Kettenbach, Arminja N., Myers, Lawrence C., Hogan, Deborah A.“…Ssn3, also known as Cdk8, is a member of the four protein Cdk8 submodule within the multi-subunit Mediator complex involved in the co-regulation of transcription. …”
Publicado 2022
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1885“…HIV infection results in defective CD8(+) T cell functions that are incompletely resolved by antiretroviral therapy (ART) except in natural controllers, who have functional CD8(+) T cells associated with viral control. …”
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1886por Darwish, Salma, Ghazy, Ehab, Heimburg, Tino, Herp, Daniel, Zeyen, Patrik, Salem-Altintas, Rabia, Ridinger, Johannes, Robaa, Dina, Schmidtkunz, Karin, Erdmann, Frank, Schmidt, Matthias, Romier, Christophe, Jung, Manfred, Oehme, Ina, Sippl, Wolfgang“…The present work describes the development of proteolysis targeting chimeras (PROTACs) of HDAC8 based on substituted benzhydroxamic acids previously reported as potent and selective HDAC8 inhibitors. …”
Publicado 2022
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1887“…There is mounting evidence on the implication of SLC6A8 in the initiation and progression of human cancers. …”
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1888por Szaniszló, Tamás, Fülöp, Máté, Pajkos, Mátyás, Erdős, Gábor, Kovács, Réka Ágnes, Vadászi, Henrietta, Kardos, József, Dosztányi, Zsuzsanna“…Dynein light chain LC8 is a small dimeric hub protein that recognizes its partners through short linear motifs and is commonly assumed to drive their dimerization. …”
Publicado 2022
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1889por Campolo, Federica, Capponi, Chiara, Tarsitano, Maria Grazia, Tenuta, Marta, Pozza, Carlotta, Gianfrilli, Daniele, Magliocca, Fabio, Venneri, Mary A., Vicini, Elena, Lenzi, Andrea, Isidori, Andrea M., Barbagallo, Federica“…Here we demonstrate that human Leydig cells express both PDE8A and PDE8B isoforms. Interestingly, we found that the expression of PDE8B but not of PDE8A is increased in transformed Leydig cells (Leydig cell tumors-LCTs) compared to non-tumoral cells. …”
Publicado 2022
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1890por Kunz, Lukas, Sotiropoulos, Alexandros G., Graf, Johannes, Razavi, Mohammad, Keller, Beat, Müller, Marion C.“…The first one comprised amino acid polymorphisms at a single position along the AvrPm8 protein, which we confirmed to be crucial for the recognition by Pm8. …”
Publicado 2023
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1891por Petrogiannis-Haliotis, Tina, Pehr, Kevin, Roberge, David, Rys, Ryan N., Monczak, Yury, Popradi, Gizelle, Ajjamada, Lissa, Benlimame, Naciba, Querfeld, Christiane, Johnson, Nathalie, Knecht, Hans“…Immunohistochemistry (IHC) showed marked CD4 and CD8 positivity. Flow cytometry (FCM) showed two distinct T-cell populations, CD4+ and CD8+ (+/− PD1), with no CD4/CD8 co-expression and no loss of panT-cell markers in either T-cell subset. …”
Publicado 2023
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1892por Khan, Aftab Aslam Parwaz, Patil, Mallikarjunagouda B., Rathod, Laxmibai P., Vader, Shivalila G., Raizada, Pankaj, Singh, Pardeep, Alotaibi, Maha M., Ansari, Mohammad Omaish, Khan, Anish, Azum, Naved, Rub, Malik Abdul, Arshad, Muhammad Nadeem, Asiri, Abdullah M.“…The potential of nanocomposite membranes (NCMs) prepared by the sodium alginate polymer and embedded with synthesized zeolitic imidazole framework-8 (ZIF-8) as fillers having microporous structure in the application of separation of gaseous mixture generated by the process of methane reforming was assessed. …”
Publicado 2023
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1893por Medeiros, Roberta Salzone, França, Yasmin, Viana, Ellen, de Azevedo, Lais Sampaio, Guiducci, Raquel, de Lima Neto, Daniel Ferreira, da Costa, Antonio Charlys, Luchs, Adriana“…Rotavirus (RVA) G8 is frequently detected in animals, but only occasionally in humans. …”
Publicado 2023
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1894por Lee, Brenda, Church, Michael, Hokamp, Karsten, Alhussain, Mohamed M., Bamagoos, Atif A., Fleming, Alastair B.“…However, despite years of study, a full understanding of the contribution of Tup1p and Cyc8p to complex function is lacking. We examined TUP1 and CYC8 single and double deletion mutants and show that CYC8 represses more genes than TUP1, and that there are genes subject to (i) unique repression by TUP1 or CYC8, (ii) redundant repression by TUP1 and CYC8, and (iii) there are genes at which de-repression in a cyc8 mutant is dependent upon TUP1, and vice-versa. …”
Publicado 2023
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1895por Rivera, Augusto, Osorio, Héctor Jairo, Sadat-Bernal, John, Eigner, Václav, Dušek, Michal“…The title chiral quaternary ammonium salt, C(13)H(25)N(4) (+)·I(−), was synthesized through the Menschutkin reaction between the cage aminal (2S,7S)-1,8,10,12-tetraazatetracyclo[8.3.1.1(8,12).0(2,7)]pentadecane and ethyl iodide. …”
Publicado 2012
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1896
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1897por Ma, Yuan-Yuan, Yan, Miao, Li, Hai-Ru, Wu, Yan-Bo, Tian, Xin-Xin, Lu, Hai-Gang, Li, Si-Dian“…Bullvalene C(10)H(10) and its analogs semibullvalene C(8)H(8), barbaralane C(9)H(10), and 9-Borabarbaralane C(8)BH(9) are prototypical fluxional molecules with rapid Cope rearrangements at finite temperatures. …”
Publicado 2019
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1898por Mizutani, Ayumu, Sabu, Yusuke, Naoi, Sotaro, Ito, Shogo, Nakano, Satoshi, Minowa, Kei, Mizuochi, Tatsuki, Ito, Koichi, Abukawa, Daiki, Kaji, Shunsaku, Sasaki, Mika, Muroya, Koji, Azuma, Yoshihiro, Watanabe, Satoshi, Oya, Yuki, Inomata, Yukihiro, Fukuda, Akinari, Kasahara, Mureo, Inui, Ayano, Takikawa, Hajime, Kusuhara, Hiroyuki, Bessho, Kazuhiko, Suzuki, Mitsuyoshi, Togawa, Takao, Hayashi, Hisamitsu“…Adenosine triphosphatase phospholipid transporting 8B1 (ATP8B1) deficiency, an ultrarare autosomal recessive liver disease, includes severe and mild clinical forms, referred to as progressive familial intrahepatic cholestasis type 1 (PFIC1) and benign recurrent intrahepatic cholestasis type 1 (BRIC1), respectively. …”
Publicado 2020
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1899
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1900“…Kristallogr. 204, 289–291] of the title compound, C(20)H(8)Cl(12), is monoclinic with Z′ = 1, whereas the 90 K structure reported herein is triclinic with Z′ = 2 and shows a 2% volume contraction. …”
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