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10121por Schmidt, Wolfgang A., Dasgupta, Bhaskar, Sloane, Jennifer, Giannelou, Angeliki, Xu, Yuqing, Unizony, Sebastian H., Mackie, Sarah L., Gonzalez-Gay, Miguel A., Spiera, Robert, Warrington, Kenneth J., Villiger, Peter M., Nivens, Michael C., Akinlade, Bolanle, Lin, Yong, Buttgereit, Frank, Stone, John H.“…METHODS: This Phase 3, double-blind study comprised a 52-week treatment period and a 24-week follow-up phase. Eligible GCA patients were randomized to receive sarilumab 200 mg (SAR200 + 26W) or 150 mg (SAR150 + 26W) with a 26-week GC taper, or placebo with a 52-week (PBO + 52W) or 26-week (PBO + 26W) GC taper. …”
Publicado 2023
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10122por Banerjee, Dithi, Sasidharan, Anjana, Gummersheimer, Stephanie, Petty, Sydnie, Hayes, Amanda M, Dhar, Minati, Selvarangan, Rangaraj“…CDC PCR assays performed on samples with discrepant results confirmed 3/13 Flu A, 24/33 SARS-CoV-2 and 9/15 RSV detections with 50% samples being missed with CT < 35. …”
Publicado 2023
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10123por Evans, W Douglas, Wallace Bihm, Jasmine, Szekely, Daniel, Nielsen, Peter, Murray, Elizabeth, Abroms, Lorien, Snider, Jeremy“…Investigators conducted a baseline assessment using a 24-item, self-administered online survey of attitudes and behaviors related to Text4baby message content. …”
Publicado 2014
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10124por O’Byrne, Paul M., D’Urzo, Tony, Beck, Ekkehard, Fležar, Matjaž, Gahlemann, Martina, Hart, Lorna, Blahova, Zuzana, Toorawa, Robert, Beeh, Kai-Michael“…PFTs were performed over a 24-hour dosing interval after 4 weeks; primary end point was FEV(1) area under the curve from 0–24 hours (AUC(0–24)) response (change from study baseline [mean FEV(1)] after 4 weeks). …”
Publicado 2015
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10125por Davis, Max, Stafford, Patrick L., Jergenson, Matthew, Bedi, Asheesh, Mendias, Christopher“…RESULTS: Compared with controls, rats that had a chronic supraspinatus tear but did not undergo repair had a 35% decrease in muscle mass compared to controls, while rats that had a chronic tear and also underwent repair had a 24% decrease in wet mass compared to controls (Fig 1D). …”
Publicado 2014
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10126“…All patients were prospectively followed for bleeding with a 24-h inpatient observation. An intervention for a bleeding complication (BL-I) was defined by undergoing a procedure (cystoscopy, embolization), receiving a blood transfusion (BL-T), death and/or readmission related to the biopsy. …”
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10127“…METHODS: The Malaysian Physical Activity for Health Study ((my)PAtHS) was a 24-week, 2-arm, parallel randomized controlled trial conducted in urban Malaysia. …”
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10128por Campbell, Bill I., Colquhoun, Ryan J., Zito, Gina, Martinez, Nic, Kendall, Kristina, Buchanan, Laura, Lehn, Matt, Johnson, Mallory, St. Louis, Courtney, Smith, Yasmin, Cloer, Brad“…On their first visit, participants arrived to the laboratory after an overnight fast and a 24-h avoidance of exercise, and underwent a baseline RMR, HR, and BP assessment. …”
Publicado 2016
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10129por Kemp, H. I., Bantel, C., Gordon, F., Brett, S. J., Laycock, H. C., Bampoe, Sohail, Bantel, Carsten, Gooneratne, Mevan, Highton, David, Hopkins, Phil, Johnston, Carolyn, Odor, Peter, Kemp, Harriet, Laycock, Helen, Martin, Daniel, O'Carroll, James, Phillips, Sioned, Visram, Anil, Siddique, Omar, Burdett, Edward, May, Rosie, Renwick, Sonia, Gray, Martin, Spiro, Michael, Luoma, Val, Chamarette, Holly, Young, Trudy, Wagstaff, Duncan, Lewith, Henry, Gowrie, Shan, Bramall, Jon, Collison, Lucy, Mansell, Josephine, Hamilton, Kevin, Leigh, Alexander, Dawson, Jeremy, Morkane, Clare, Balla, Paul, Shukla, Bhavin, Rublotta, Francesca, Cousins, Jonathan, Magee, David, Cashell, Catherine, Kooner, Gurleen, Arnold, Glenn, Garnelo Ray, Vanessa, Clancy, Olivia, Whitehead, Nicole, Kooner, Gurleen, Handy, Jonathan, Vizcaychipi, Marcella, Edwards, Zara, Davis‐Hall, Melanie, Addy, Melissa, Jhanji, Shaman, Wigmore, Tim, Christie, Linsey, Sidon, Lauren, Grover, Munita, Panagoda, Prasan, Howells, Lara, Cartwright, Charles, Doyle, Richard, Griffith, Megan, Casely, Emma, Holdgate, Andrew, Rich, Stephanie, Henriksson, Maria, Jaggar, Sian, Tatham, Kate, Kadry, Mirian, Finlay, Claire, Pandit, Ajoy, Mehdipour, Savviz, Ong, Cheng, Bidd, Heena, Ramessur, Suneil, Anwar, Sibtain, Blunt, Nadia, Williams, Hannah, Tosini, Chiara, Parini, Alessandra, Kumar, Ravi, Ferrier, Victoria, Gupta, Aman, Canavan, Aoife, Dickinson, Matt, Carey, Ben, Somasundaram, Karthik, De Silva, Samanthi, Moghulm, Arif, Dua, Kanika, McHugh, Barry, Chapman, Rachel, Peck, Marcus, Sangam, Amy, Al‐Sahaf, Hadi, Gowripalann, Tharumalingam, Kunnumpurath, Sreekumar, Mottaleb, Ramy, Fletcher, Kate, Bhagwat, Milind, Eeles, Alex, Hunningher, Annie, Nesbit, Finn, Turton, Danny, Barringer, Chris, Dannatt, Peter, Shenoy, Venkat, Keogh, Peter, Krishnachetty, Bobby, Mendes, Fiona, Ferns, Janis, Kennedy, Charles, Sandru, Roxana, Husain, Naush, Holler, Liesel, Barnes, Lucy, Thorburn, Patrick, Shippam, William, Lee, Sindy, Mahgoub, Sara“…This observational service evaluation considered all pain and analgesia‐related entries in patients’ records over a 24‐h period, in 45 adult intensive care units (ICUs) in London and the South‐East of England. …”
Publicado 2017
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10130por Rye Hanton, Cassia, Kwon, Yong-Jun, Aung, Thawda, Whittington, Jackie, High, Robin R, Goulding, Evan H, Schenk, A Katrin, Bonasera, Stephen J“…These metrics were compared to our mobile phone-based metrics collected from the participants in the community over a 24-hour period occurring within 1 week of the initial assessment. …”
Publicado 2017
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10131por Guaita‐Esteruelas, Sandra, Saavedra‐García, Paula, Bosquet, Alba, Borràs, Joan, Girona, Josefa, Amiliano, Kepa, Rodríguez‐Balada, Marta, Heras, Mercedes, Masana, Luís, Gumà, Josep“…Breast cancer patients had a 24.8% (p < .0001) and 11.4% (p < .05) higher blood concentration of FABP4 and FABP5, respectively. …”
Publicado 2017
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10132por Novak, Petr, Schmidt, Reinhold, Kontsekova, Eva, Kovacech, Branislav, Smolek, Tomas, Katina, Stanislav, Fialova, Lubica, Prcina, Michal, Parrak, Vojtech, Dal-Bianco, Peter, Brunner, Martin, Staffen, Wolfgang, Rainer, Michael, Ondrus, Matej, Ropele, Stefan, Smisek, Miroslav, Sivak, Roman, Zilka, Norbert, Winblad, Bengt, Novak, Michal“…Previously, we reported a 24-week phase 1 trial on the active vaccine AADvac1 against pathological tau protein; here, we present the results of a further 72 weeks of follow-up on those patients. …”
Publicado 2018
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10133por Klein, Nicola S, Bockting, Claudi LH, Wijnen, Ben, Kok, Gemma D, van Valen, Evelien, Riper, Heleen, Cuijpers, Pim, Dekker, Jack, van der Heiden, Colin, Burger, Huibert, Smit, Filip“…The economic evaluation was performed from a societal perspective with a 24-month time horizon. The health outcomes were number of depression-free days according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, (DSM-IV) criteria assessed with the Structured Clinical Interview for DSM-IV axis I disorders by blinded interviewers after 3, 12, and 24 months. …”
Publicado 2018
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10134por Beasley, Liam, Smith, Lee, Antonio, Jose, Gordon, Dan, Johnstone, James, Roberts, Justin“…METHODS: Following University Ethics approval, twenty-seven healthy, male rowers (age: 24 ± 2 years; body-height: 1.81 ± 0.02 m; body-mass: 82.3 ± 2.5 kg; body-fat: 14.2 ± 1.0%) were randomised in a double-blind manner to 4 weeks of: i) βA (2.4 g·d(− 1), βA1); ii) matched total βA (4.8 g on alternate days, βA2); or iii) cornflour placebo (2.4 g·d(− 1), PL). …”
Publicado 2018
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10135por Gadelha, Mônica, Colao, Annamaria, Bex, Marie, Campigotto, Federico, Bartalotta, Amy, Maamari, Ricardo, Raverot, Gérald“…Background: In a 24-week, Phase 3 study (PAOLA), long-acting pasireotide demonstrated superior efficacy (GH <2.5 µg/L and IGF-1 <ULN) over continued treatment with long-acting octreotide/lanreotide in pts with uncontrolled acromegaly (Gadelha MR, et al. …”
Publicado 2019
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10136por Biller, Beverly MK, Newell-Price, John, Fleseriu, Maria, Bertagna, Xavier, Findling, James, Shimatsu, Akira, Lee, Eun Jig, Gu, Feng, Auchus, Richard, Leelawattana, Rattana, Lacroix, André, Kim, Jung Hee, Laplanche, Audrey, O'Connell, Paul, Tauchmanova, Libuse, Pedroncelli, Alberto, Pivonello, Rosario“…Methods: Phase III, multicenter, double-blind, randomized withdrawal study following a 24-week, open-label, single-arm treatment phase. …”
Publicado 2019
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10137por Müller, Ivan, Smith, Danielle, Adams, Larissa, Aerts, Ann, Damons, Bruce P, Degen, Jan, Gall, Stefanie, Gani, Zaahira, Gerber, Markus, Gresse, Annelie, van Greunen, Darelle, Joubert, Nandi, Marais, Tracey, Nqweniso, Siphesihle, Probst-Hensch, Nicole, du Randt, Rosa, Seelig, Harald, Steinmann, Peter, Utzinger, Jürg, Wadhwani, Christina, Walter, Cheryl, Pühse, Uwe“…For school children, the study is designed as a 36-week, cluster RCT (KaziKidz intervention), whereas for teachers, a 24-week intervention phase (KaziHealth intervention) is planned. …”
Publicado 2019
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10138por Lefler, Leanne L, Rhoads, Sarah J, Harris, Melodee, Funderburg, Ashley E, Lubin, Sandra A, Martel, Isis D, Faulkner, Jennifer L, Rooker, Janet L, Bell, Deborah K, Marshall, Heather, Beverly, Claudia J“…OBJECTIVE: This study aimed to compare perspectives of older adults with HF who were randomized to either (1) mHealth equipment connected to a 24-hour call center, (2) digital home equipment, or (3) standard care, with regard to ease and satisfaction with equipment, provider communication and engagement, and ability to self-monitor and manage their disease. …”
Publicado 2018
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10139“…OBJECTIVE: We aimed to assess the effectiveness of an 8-week, tailored, Web-based exercise intervention for cardiorespiratory fitness improvement, expressed as peak oxygen uptake (peak volume of oxygen [VO(2peak)]), in patients with histologically confirmed NAFLD. METHODS: In a 24-month period, 44 patients were enrolled into an 8-week, prospective, single-arm study with 12 weeks of follow-up. …”
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10140por Perez Kerkvliet, Carlos, Dwyer, Amy R., Diep, Caroline H., Oakley, Robert H., Liddle, Christopher, Cidlowski, John A., Lange, Carol A.“…Both pS134-GR and expression of the MAPK-scaffolding molecule 14-3-3ζ were essential for a functionally intact p38 MAPK signaling pathway downstream of MAP3K5/ASK1, indicative of a feedforward signaling loop wherein self-perpetuated GR phosphorylation enables cancer cell autonomy. A 24-gene pS134-GR-dependent signature induced by TGFβ1 predicts shortened overall survival in breast cancer patients. …”
Publicado 2020
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