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561por Yang, Dakai, Yuan, Qinggong, Balakrishnan, Asha, Bantel, Heike, Klusmann, Jan-Henning, Manns, Michael P., Ott, Michael, Cantz, Tobias, Sharma, Amar Deep“…The lack of broad-spectrum anti-acute liver failure (ALF) therapeutic agents contributes to ALF-related mortality. …”
Publicado 2016
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562“…BACKGROUND/AIMS: Acute liver failure (ALF) is a rare but severe medical emergency. To date, there is no established treatment for non-acetaminophen-induced acute liver failure (NAI-ALF) other than liver transplantation, and little is known about the use of N-acetylcysteine (NAC) in NAI-ALF. …”
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563por Chen, Qian, Wang, Yao, Jiao, Fangzhou, Cao, Pan, Shi, Chunxia, Pei, Maohua, Wang, Luwen, Gong, Zuojiong“…Acute liver failure (ALF) is a rare and critical medical condition. This study was designed to investigate the protective effects and underlying mechanism of ACY1215 in ALF mice. …”
Publicado 2021
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564por Bartley, Mairead, Manggaard, Jennifer, Fischer, Karen, Holland, Diane, Takahashi, Paul“…RESULTS: Of 1203 people with dementia, 581 (48.3%) were living in a SNF and 622 (51.7%) in the home/ALF. At least one hospitalization was recorded for 70.7% in the home/ALF compared with 50.8% in the SNF (p< 0.01), similar to ED visits (80.2% versus 58% in home/ALF and SNF groups, respectively, p< 0.01). …”
Publicado 2022
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565por Kotoh, Kazuhiro, Ueda, Akihiro, Tanaka, Masatake, Miyazaki, Masayuki, Kato, Masaki, Kohjima, Motoyuki, Enjoji, Munechika, Nakamuta, Makoto, Takayanagi, Ryoichi“…Although the mechanism underlying acute liver failure (ALF) has not been clarified, recent reports indicate overactivation of macrophages is involved in its progression. …”
Publicado 2009
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566“…Accelerated long-term forgetting (ALF) is a memory disorder that manifests by a distinct pattern of normal memory for up to an hour after learning, but an increased rate of forgetting during the subsequent hours and days. …”
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567por Melgaço, Juliana Gil, Soriani, Frederico Marianetti, Sucupira, Pedro Henrique Ferreira, Pinheiro, Leonardo Assaf, Vieira, Yasmine Rangel, de Oliveira, Jaqueline Mendes, Lewis-Ximenez, Lia Laura, Araújo, Cristina Carvalho Vianna, Pacheco-Moreira, Lúcio Filgueiras, Menezes, Gustavo Batista, Cruz, Oswaldo Gonçalves, Vitral, Claudia Lamarca, Pinto, Marcelo Alves“…The groups were divided into viral- and non-viral-induced self-limited AH and ALF. Thus, we worked with five groups: Hepatitis A virus (HAV)-induced self-limited acute hepatitis (HAV-AH), HAV-induced ALF (HAV-ALF), non-viral-induced self-limited acute hepatitis (non-viral AH), non-viral-induced acute liver failure (non-viral ALF), and healthy subjects (HC). …”
Publicado 2016
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568por Zhang, Yan-zhuo, Wei, Xiong-li, Tang, Bin, Qin, Yuan-yuan, Ou, Min, Jiang, Xiao-hong, Tan, Yu-feng, Ye, Mao-ying“…Results: The incidence of EA was 50% in the control group, 25% in the DEX group, and 5% in the DEX + Alf1 group, and it never happened in the DEX + Alf2 group. …”
Publicado 2022
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569por Trehanpati, Nirupma, Sehgal, Rashi, Patra, Sharda, Vyas, Ashish, Vasudevan, Madavan, Khosla, Ritu, Khanam, Arshi, Kumar, Guresh, Maiwall, Rakhi, Ramakrishna, Gayatri, Kottilil, Shyam, Sarin, Shiv Kumar“…We investigated their role as a biomarker in predicting ALF due to HEV (ALF-E). METHODS: We performed next generation sequencing and subsequent validation studies in PBMCs of pregnant (P) self limiting AVH-E, ALF due to HEV (ALF-E) and compared with AVH-E in non-pregnant (NP) females and healthy controls. …”
Publicado 2017
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570por Huang, Sha, Wang, Yuhua, Xie, Shunwen, Lai, Yuqi, Mo, Chan, Zeng, Ting, Kuang, Shanshan, Deng, Guanghui, Zhou, Chuying, Chen, Yuyao, Huang, Shaohui, Gao, Lei, Lv, Zhiping“…Ferroptosis may be involved in ALF. Indeed, emerging studies have shown that ferroptosis plays a significant role in ALF. …”
Publicado 2022
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571por Anene, Doreen O., Akter, Yeasmin, Thomson, Peter C., Groves, Peter, O'Shea, Cormac J.“…In Phase 2 (P2), 41 to 46 weeks, the TRF hens were transitioned to ALF status while the ALF and PRF hens remained as in P1. …”
Publicado 2023
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572“…C-peptide and serpin E1 were not detected in ALF for any individual, and IL-6, IL-10, and TNF-alpha were not detected in either ALF or serum for any individual. …”
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573por Lin, Xin, Cui, Ming, Xu, Dong, Hong, Dubeiqi, Xia, Yan, Xu, Chentong, Li, Riyong, Zhang, Xuan, Lou, Yaxin, He, Qihua, Lv, Ping, Chen, Yingyu“…Acute liver failure (ALF) is an inflammation-mediated hepatocellular injury process associated with cellular autophagy. …”
Publicado 2018
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574por Jin, Yuanyuan, Wang, Haixia, Yi, Ke, Lv, Shixian, Hu, Hanze, Li, Mingqiang, Tao, Yu“…However, a satisfactory therapeutic option for curing ALF is still absent, other than liver transplantation. …”
Publicado 2020
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575por Rao, Ashwin, Rule, Jody A., Cerro-Chiang, Giuliana, Stravitz, Richard T., McGuire, Brendan M., Lee, Goo, Fontana, Robert J., Lee, William M.“…BACKGROUND: While hepatitis A and B are well-known causes of acute liver failure (ALF), few well-documented cases of hepatitis C virus (HCV) infection (absent preexisting liver disease or other liver insults) have been described that result in ALF. …”
Publicado 2022
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576por Fang, Jun, Kuang, Jing, Hu, Shuli, Yang, Xiuhong, Wan, Weibo, Li, Jing, Fan, Xuepeng“…OBJECTIVE: It has been evidenced that microRNAs (miRs) exert crucial effects on acute liver failure (ALF), while the detailed function of miR‐450b‐5p in ALF progression remained obscure. …”
Publicado 2023
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577“…FcALF2 was one isoform of ALFs isolated from the Chinese shrimp Fenneropenaeus chinensis. …”
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578por Guo, Gang, Zhu, Yongjie, Wu, Zhenru, Ji, Hongjie, Lu, Xufeng, Zhou, Yongjie, Li, Yuanmin, Cao, Xiaoyue, Lu, Yanrong, Talbot, Prue, Liao, Jiayu, Shi, Yujun, Bu, Hong“…Here, using an amatoxin‐induced rhesus monkey model of ALF, we panoramically revealed the cellular and molecular events that lead to the development of ALF. …”
Publicado 2018
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579por Abenavoli, Ludovico, Maurizi, Valentina, Boccuto, Luigi, Di Berardino, Arianna, Giostra, Nena, Santori, Pierangelo, Scarcella, Maria Laura, Procopio, Anna Caterina, Rasetti, Carlo, Scarpellini, Emidio“…Acute liver failure (ALF) presents with an acute abnormality of liver blood tests in an individual without underlying chronic liver disease. …”
Publicado 2022
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580por Anastasiou, Olympia, Sydor, Svenja, Sowa, Jan-Peter, Manka, Paul, Katsounas, Antonios, Syn, Wing-Kin, Führer, Dagmar, Gieseler, Robert K., Bechmann, Lars P., Gerken, Guido, Moeller, Lars C., Canbay, Ali“…The present study evaluates potential correlations of select thyroid functional parameters with ALF. METHODS: 84 consecutively recruited ALF patients were grouped according to the outcome of ALF (spontaneous recovery: SR; transplantation or death: NSR). …”
Publicado 2015
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