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  1. 721
    “…Furthermore, GSK3β activity in the CHB patients was increased in the phase of ALF. CONCLUSIONS: Results indicate that GSK3β activation contributes to liver injury by participating in oxidative stress response in ALF and is, therefore, a potential therapeutic target for ALF.…”
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    Oxidative stress promotes d-GalN/LPS-induced acute hepatotoxicity by increasing glycogen synthase kinase 3β activity
  2. 722
    “…BACKGROUND & AIMS: The etiology of acute liver failure (ALF) remains elusive in almost half of affected children. …”
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    Deep Sequencing Reveals Novel Genetic Variants in Children with Acute Liver Failure and Tissue Evidence of Impaired Energy Metabolism
  3. 723
    “…BACKGROUND & AIMS: Acute liver failure (ALF) is a condition with high mortality and morbidity. …”
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    Mechanisms of fibrosis in acute liver failure
  4. 724
    “…PURPOSE: To examine the efficacy of TachoSil for vessel injury in 6 patients who underwent anterior lumbar fusion surgery (ALF). OVERVIEW OF LITERATURE: ALF for the lumbar spine has a high rate of success, although intraoperative concerns and iatrogenic complications are known, and injury of a major vessel is sometimes a complication. …”
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    Efficacy of TachoSil, a Fibrin-Based Hemostat, for Anterior Lumbar Spine Surgery
  5. 725
    “…It is unclear which methods are the best to diagnose MLD in the setting of ALF. OBJECTIVE: The aim of the study was to determine the incidence of MLD in children younger than 2 years with ALF and the utility of routine investigations to detect MLD. …”
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    Incidence of Primary Mitochondrial Disease in Children Younger Than 2 Years Presenting With Acute Liver Failure
  6. 726
    “…Effective treatments for acute liver failure (ALF) are still lacking. We recently reported that a single intravenous administration of serum-free conditioned medium from stem cells derived from human exfoliated deciduous teeth (SHED-CM) into the D-galactosamine (D-Gal)-induced rat ALF model improves the liver injury. …”
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    Secreted Ectodomain of SIGLEC-9 and MCP-1 Synergistically Improve Acute Liver Failure in Rats by Altering Macrophage Polarity
  7. 727
    “…CONCLUSION: ALF-OFs is a new prognostic score in acetaminophen-related ALF that can predict both the need for liver transplant and high risk of transplant futility, improving candidate selection for liver transplantation.…”
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    Development of an organ failure score in acute liver failure for transplant selection and identification of patients at high risk of futility
  8. 728
    “…Hepatitis B virus-associated acute liver failure (HBV-ALF) is a rare but life-threatening syndrome that carried a high morbidity and mortality. …”
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    Identification of key candidate genes and pathways in hepatitis B virus-associated acute liver failure by bioinformatical analysis
  9. 729
    “…The LPS-binding domain (LBD) contributes to the major antimicrobial activity of ALF. However, LBDs from different ALFs share low sequence similarity. …”
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    Characterization of a Lymphoid Organ Specific Anti-lipopolysaccharide Factor From Shrimp Reveals Structure-Activity Relationship of the LPS-Binding Domain
  10. 730
    “…This study aimed to determine the effects, therapeutic window and mechanisms of selonsertib, a selective inhibitor of ASK1, for ALF therapy. RESULTS: Lipopolysaccharide and d-galactosamine (LPS/GalN) were used to simulate ALF. …”
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    Selonsertib, a potential drug for liver failure therapy by rescuing the mitochondrial dysfunction of macrophage via ASK1–JNK–DRP1 pathway
  11. 731
    “…However, some concerns were raised as to their possible association with acute liver failure (ALF). The aim of this study is to assess ALF risk within 30 days of receiving a systemically administered quinolone antibiotic, in individuals with no history of liver/diseases. …”
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    Systemic quinolones and risk of acute liver failure III: A nested case–control study using a US electronic health records database
  12. 732
    “…Acute liver failure (ALF) is a disorder defined by coagulopathy and encephalopathy with a poor prognosis. …”
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    Transcatheter arterial steroid injection therapy improves the prognosis of patients with acute liver failure
  13. 733
    “…Materials and Methods. ALF was induced in Wistar rats by administrating D-GalN (900 mg/kg) and lipopolysaccharide (10 μg/kg). …”
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    Herbal Compound “Jiedu Huayu” Reduces Liver Injury in Rats via Regulation of IL-2, TLR4, and PCNA Expression Levels
  14. 734
    por Dalhoff, Kim
    Publicado 2017
    “…However, less than 10% of all liver transplants are performed in patients with ALF [5, 6].…”
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    Toxicant-Induced Hepatic Injury
  15. 735
    “…Acute liver failure (ALF) is a life-threatening consequence of hepatic function rapid loss without preexisting liver disease. …”
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    Insight into microRNAs-Mediated Communication between Liver and Brain: A Possible Approach for Understanding Acute Liver Failure?
  16. 736
    “…Acute liver failure (ALF) is a mortal and critical hepatic disease, in which oxidative stress, inflammation storm and hepatocyte death are crucial in the pathogenesis. …”
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    Liposome cocktail activator modulates hepatocytes and remodels the microenvironment to mitigate acute liver failure
  17. 737
    “…Acute liver failure (ALF) is the rapid onset of severe liver dysfunction, defined by the presence of hepatic encephalopathy and impaired synthetic function (international normalized ratio of ≥1.5) in the absence of underlying liver disease. …”
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    Clinical Considerations of Coagulopathy in Acute Liver Failure
  18. 738
    “…BACKGROUND: Acute liver failure (ALF) may represent an indication for liver transplantation (LT). …”
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    Sequential Use of High-Volume Plasma Exchange and Continuous Renal Replacement Therapy in Hepatitis B Virus-Related Acute Liver Failure: A Case Report
  19. 739
    “…In present study, we investigated Ca(2+) mobilization induced by aluminum fluoride (AlF(4)(-)), a G-protein activator, with or without RANKL and the effects of AlF(4)(-) on the osteoclastogenesis in primary cultured mouse bone marrow-derived macrophages (BMMs). …”
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    Activation of G Proteins by Aluminum Fluoride Enhances RANKL-Mediated Osteoclastogenesis
  20. 740
    “…Despite aggressive intensive medical management acute liver failure (ALF) may require high-urgency liver transplantation (LTx). …”
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    Application of the Liver Maximum Function Capacity Test in Acute Liver Failure: A Helpful Tool for Decision-Making in Liver Transplantation?
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