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741por Moliva, Juan I., Hossfeld, Austin P., Canan, Cynthia H., Dwivedi, Varun, Wewers, Mark D., Beamer, Gillian, Turner, Joanne, Torrelles, Jordi B.“…We hypothesized that ALF-induced modification of BCG would induce better protection against aerosol infection with M.tb. …”
Publicado 2017
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742por Chen, Li, Zhang, Jiexin, Yang, Lu, Zhang, Guoying, Wang, Yingjie, Zhang, Shichang“…Mesenchymal stem cells (MSCs) and hepatocytes are two attractive sources of cell-based therapies for acute liver failure (ALF). The cotransplantation of hepatocytes with MSCs can improve the therapeutic performance for the treatment of ALF. …”
Publicado 2018
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743por Chen, Huadi, Zhao, Wenting, Zhang, Yixi, Guo, Yiwen, Luo, Weixin, Wang, Xiaobo, Nie, Yu, Ye, Maodong, Huang, Changjun, Wang, Dongping, Chen, Maogen, He, Xiaoshun, Zhao, Qiang“…Acute liver failure (ALF) caused by hepatitis B virus (HBV) is common type of liver failure in the world, with high morbidity and mortality rates. …”
Publicado 2020
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744“…Drug-induced liver injury (DILI), which refers to liver damage caused by a drug or its metabolites, has emerged as an important cause of acute liver failure (ALF) in recent years. Chemically-induced ALF in animal models mimics the pathology of DILI in humans; thus, these models are used to study the mechanism of potentially effective treatment strategies. …”
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745por Lee, Yu-Mi, Choi, Dong-Hee, Cheon, Min-Woo, Kim, Jae Gwan, Kim, Jeong-Sang, Shin, Myung-Geun, Kim, Hye-Ran, Youn, Daehwan“…In this study, we examined if acupuncture at LR3 can affect mitochondria-related gene expression in a liver damage model of experimentally induced acute liver failure (ALF). ALF was induced by the intraperitoneal injection of D-galactosamine (D-GalN) in experimental rats, who then received either sham (ALF), manual acupuncture (MA), electroacupuncture (EA), or silymarin (PC, positive control) treatment. …”
Publicado 2022
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746por Lin, Jiacheng, Ling, Qihua, Yan, Liang, Chen, Bowu, Wang, Fang, Qian, Yihan, Gao, Yueqiu, Wang, Qian, Wu, Hailong, Sun, Xuehua, Shi, Yanjun, Kong, Xiaoni“…Background: Acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) are characterized by systemic inflammation and high mortality, but there is no effective clinical treatment. …”
Publicado 2022
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747“…BACKGROUND: Acute liver failure (ALF) is a syndrome of severe hepatocyte injury with high rate of mortality. …”
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748por Li, Shanshan, Wang, Junfeng, Jiang, Bin, Jiang, Jiang, Luo, Lilin, Zheng, Bingrong, Si, Wei“…At present, it is difficult to know which type of MSC is most suitable for acute liver failure (ALF), and there is no parallel study to compare MSCs from different tissues of the same donor. …”
Publicado 2022
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749por Atherton, Kathryn E., Nobre, Anna C., Lazar, Alpar S., Wulff, Katharina, Whittaker, Roger G., Dhawan, Vandana, Lazar, Zsolt I., Zeman, Adam Z., Butler, Christopher R.“…In stark contrast, the more SWS, the smaller the sleep-related memory benefit in the ALF group. Therefore, contrary to its role in healthy people, SWS-associated brain activity appears to be deleterious for memory in patients with ALF.…”
Publicado 2016
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750“…We study the relationship between ALF bed market capacity and NH case mix in a state (Virginia) where ALF bed capacity stabilized after a period of growth. …”
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751por Ince, V., Kayaalp, C., Otan, E., Ozdemir, F., Dirican, A., Toprak, H. I., Aydin, C., Ara, C., Yilmaz, S.“…Emergency liver transplantation (LT) for acute liver failure (ALF) is a life-saving treatment. Occurrence of this situation in the same patient twice is very rare. …”
Publicado 2018
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752por Scordo, Julia M., Arcos, Jesús, Kelley, Holden V., Diangelo, Lauren, Sasindran, Smitha J., Youngmin, Ellie, Wewers, Mark D., Wang, Shu-Hua, Balada-Llasat, Joan-Miquel, Torrelles, Jordi B.“…Our results show that ALF fragments activate neutrophils leading to an increased production of inflammatory cytokines and oxidative radicals. …”
Publicado 2017
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753“…BACKGROUND: Acute liver failure (ALF) may result in elevated intracranial pressure (ICP). …”
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754por Takeda, Satoshi, Saito, Mitsuru, Sakai, Sadaoki, Yogo, Kenji, Marumo, Keishi, Endo, Koichi“…All doses of ELD and the highest dose of ALF reduced urinary DPD excretion, but had no effect on serum OC. …”
Publicado 2017
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755“…BACKGROUND: Acute liver failure (ALF) is an acute inflammatory liver disease with high mortality. …”
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756por Driever, Ellen G., Stravitz, R. Todd, Zhang, Jingwen, Adelmeijer, Jelle, Durkalski, Valerie, Lee, William M., Lisman, Ton“…Rodent models have shown a link between intrahepatic microthrombus formation and progression of ALF. We sought to confirm these earlier findings in a large series of patients with well‐characterized ALF from the Acute Liver Failure Study Group. …”
Publicado 2021
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757por Chen, Dazhi, Zeng, Ruichao, Teng, Guigen, Cai, Chao, Pan, Tongtong, Tu, Hanxiao, Lin, Hongwei, Du, Qingjing, Wang, Huahong, Chen, Yongping“…This study aims to explore the efficacy and potential mechanism of MenSCs to cure ALF. METHODS: We investigate the potential mechanism of MenSCs on the ALF in vitro and in vivo. …”
Publicado 2021
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758por Xie, Chencheng, Fenkel, Jonathan M., Halegoua-DeMarzio, Dina L., Civan, Jesse M., Tholey, Danielle M., Herrine, Steven K., Thapar, Manish, Ambelil, Manju, Arastu, Sanaa, Frank, Adam M., Shah, Ashesh P., Glorioso, Jamie M., Ramirez, Carlo G., Bodzin, Adam S., Maley, Warren R., Sass, David A.“…We are reporting a series of four cases of acute liver failure (ALF) requiring liver transplantation (LT) due to acute HAV. …”
Publicado 2021
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759por Yuan, Chunchun, Fan, Jinghui, Jiang, Lai, Ye, Wenxin, Chen, Zhuo, Wu, Wenzi, Huang, Qixin, Qian, Lichun“…Acute liver failure (ALF) refers to the occurrence of massive hepatocyte necrosis in a short time, with multiple complications, including inflammatory response, hepatic encephalopathy, and multiple organ failure. …”
Publicado 2023
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760por Jin, Yuanyuan, Zhang, Jiabin, Xu, Yanteng, Yi, Ke, Li, Fenfang, Zhou, Huicong, Wang, Haixia, Chan, Hon Fai, Lao, Yeh-Hsing, Lv, Shixian, Tao, Yu, Li, Mingqiang“…Reactive oxygen species (ROS)-associated oxidative stress, inflammation storm, and massive hepatocyte necrosis are the typical manifestations of acute liver failure (ALF), therefore specific therapeutic interventions are essential for the devastating disease. …”
Publicado 2023
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