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  1. 1221
    “…A correlation was observed between CuEXC values and the severity of ALF. Cut-off values were different between young and adult rats and evolved because of age and/or liver failure. …”
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    Evolution of Exchangeable Copper and Relative Exchangeable Copper through the Course of Wilson's Disease in the Long Evans Cinnamon Rat
  2. 1222
    “…CONCLUSION: The modularity concept seems applicable to the residential care offered by the ALF of the mental healthcare institution under study. …”
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    Modular health services: a single case study approach to the applicability of modularity to residential mental healthcare
  3. 1223
    “…RESULTS: The Co(3)O(4) and CoO NPs showed about 11.46 % and 92.65 % solubility in ALF, respectively. Instillation of Co(3)O(4) NPs produced neutrophilic inflammation, but CoO NPs induced eosinophilic inflammation. …”
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    Response-metrics for acute lung inflammation pattern by cobalt-based nanoparticles
  4. 1224
    “…Presence of potential therapeutic targets among these mediators was confirmed by demonstration of in vivo activity of siRNAs against four identified target candidates that protected mice from acute liver failure (ALF), a life-threatening disease with known involvement of death receptor (DR)-mediated apoptosis. …”
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    Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure
  5. 1225
    “…The severity of acute liver failure (ALF) induced by bacterial lipopolysaccharide (LPS) is associated with the hepatic innate immune response. …”
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    PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice
  6. 1226
    “…A PT >1.5 times the upper limit of normal defined acute liver failure (ALF). RESULTS: Dogs with ALD had mean increases in R, K, LY30, PT, aPTT, and vWF activity, and decreases in angle, maximal amplitude (MA), G, AT activity, and PC activity. …”
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    Thromboelastographic Evaluation of Dogs with Acute Liver Disease
  7. 1227
    “…Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. …”
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    Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs
  8. 1228
    “…ALFPm6, a member of antimicrobial peptide in the antilipopolysaccharide factor (ALF) family from Penaeus monodon, plays important roles in shrimp immunity against pathogens. …”
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    Regulation of antilipopolysaccharide factors, ALFPm3 and ALFPm6, in Penaeus monodon
  9. 1229
    “…HE on ALF has sometimes resulted in brain death following brain edema with astrocyte swelling. …”
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    Alpha-1 antichymotrypsin is involved in astrocyte injury in concert with arginine-vasopressin during the development of acute hepatic encephalopathy
  10. 1230
    “…Pharmacological inhibition of the enterohepatic BA circulation using a luminal- restricted ASBT inhibitor, SC-435, in mice with AOM-induced ALF and STZ-HFD -induced CLD effectively reduced BA and ammonia concentrations in the blood and brain, and alleviated liver and brain damages. …”
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    Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure
  11. 1231
    “…OBJECTIVES: Jie-Du-Hua-Yu (JDHY) granule is a combination of six traditional Chinese medicines with known therapeutic effect in treating acute liver failure (ALF). The aim of this study was to investigate the amelioration efficacy of JDHY in lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced ALF in rat and explore the possible molecular mechanism underlying the therapeutic efficacy. …”
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    The underlying mechanisms of Jie-Du-Hua-Yu granule for protecting rat liver failure
  12. 1232
    “…From patient serum lipidomics, pronouncedly changed lipid species between abnormal liver function (ALF) patients and normal liver function (NLF) patients were identified. …”
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    Lipidomic Profiling Reveals Disruption of Lipid Metabolism in Valproic Acid-Induced Hepatotoxicity
  13. 1233
    “…Acute liver failure (ALF) is characterized by loss of liver function in response to sustained augmentation of the acute-phase response (APR) in the liver, which can progress even to death. …”
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    RORα suppresses interleukin-6-mediated hepatic acute phase response
  14. 1234
    “…Acetaminophen (APAP)‐induced liver injury is the most common cause of acute liver failure (ALF) in the Western world. APAP toxicity progresses to multiorgan dysfunction and thus has broader whole‐body implications. …”
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    Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability
  15. 1235
    “…To this end, MSC-based therapies may serve as an effective strategy for patients who are waiting for liver transplantation during the early and late stages of APAP-induced ALF in the near future.…”
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    Transplantation of mesenchymal stem cells and their derivatives effectively promotes liver regeneration to attenuate acetaminophen-induced liver injury
  16. 1236
    “…Acute Liver failure (ALF) is a life-threatening disease and is determined by coagulopathy (with INR ≥ 1.5) and hepatic encephalopathy as a result of severe liver injury in patients without preexisting liver disease. …”
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    Perspective of placenta derived mesenchymal stem cells in acute liver failure
  17. 1237
    “…YB(4), AlB(2) and B powders were reactively sintered with an additive AlF(3) at 1773 K for 5–60 min in reduced Ar atmosphere. …”
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    New Synthesis Route for Complex Borides; Rapid Synthesis of Thermoelectric Yttrium Aluminoboride via Liquid-Phase Assisted Reactive Spark Plasma Sintering
  18. 1238
    “…METHODS: Cafcass Cymru data was transferred to SAIL using a standardised approach to provide de-identified data with Anonymised Linking Fields (ALF) for successfully matched records. Three cohorts were created: all individuals involved in family court applications; all individuals with an ALF allowing subsequent health data linkage; and all individuals with a Residential Anonymised Linking Field (RALF) enabling area-level deprivation analysis. …”
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    Data Resource: population level family justice administrative data with opportunities for data linkage
  19. 1239
    “…BACKGROUND AND AIM: Acute severe autoimmune hepatitis (AS-AIH) is a rare cause of acute liver failure (ALF), which is often neglected and delayed in treatment. …”
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    Clinical characteristics and treatment outcomes of acute severe autoimmune hepatitis
  20. 1240
    “…BACKGROUND: To study the baseline characteristics and clinical outcome of HEV-induced ALF in a recent HEV epidemic. To detect raised ICP clinically and observe response to mannitol infusion. …”
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    Five-day outcome of hepatitis E-induced acute liver failure in the ICU
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