“…Hepatotoxicity caused by APAP overdose is one of the leading causes of acute liver failure (ALF) in the US and in some parts of Europe, limiting its clinical application. …”
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“…In its 1980 benzene decision [Industrial Union Department, ALF-CIO v. American Petroleum Institute, 448 U.S. 607 (1980)], the Supreme Court ruled that "before he can promulgate any permanent health or safety standard, the Secretary [of Labor] is required to make a threshold finding that a place of employment is unsafe--in the sense that significant risks are present and can be lessened by a change in practices" (448 U.S. at 642). …”
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“…In these complexes MgF(3)(–) and AlF(4)(–) are surrogates for the transferring phosphate. …”
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“…In this study, we biochemically and histologically characterized the effects of rh-HGF on in vitro human hepatocyte injury and mouse acute liver failure (ALF) models, both of which were induced by antibody-mediated Fas signaling. rh-HGF inhibited intracellular caspase-3/7 activation and cytokeratin 18 (CK-18) fragment release in both models. …”
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“…Moreover, PTFE could react with Al resulting in a thin AlF(3) layer, which could promote the destruction of Al(2)O(3) shell. …”
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“…The results showed that the remelting electroslag volatilized significantly above 1300°C and the volatiles were mainly CaF(2), MgF(2) with a small amount of SiF(4) and AlF(3); the continuous casting mould flux volatilization was divided into two stages, in the first stage (500°C∼800°C), CaF(2) and Na(2)O reacted to form NaF, and in the second stage (greater than 1200°C), the CaF(2) evaporation was highlighted; for CaF(2)-CaO-based refining slag, the volatilization was the most significant at the eutectic point 84% CaF(2)–16% CaO, and the volatility can be reduced by adding 5% SiO(2). …”
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“…Otherwise, the consumption of certain drugs leads to an acute liver failure (ALF), with drug-induced liver injury (DILI) as its main cause, or alcoholic liver disease (ALD). …”
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“…The outstanding performance is attributed to the composition of the cathode electrolyte interphase (CEI) containing the solid and dense LiF, AlF(3), B(2)O(3) and Li(2)CO(3). This provides a new method and idea for future electrolyte formulation optimization.…”
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“…The residues are mainly MnAl(2)O(4), MnF(2) and AlF(3) which indicates that Al/MnO(2)/PVDF energetic nanocomposite could make full use of manganese oxide. …”
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“…Orthotropic liver transplantation (OLT) is currently the most effective and established treatment for end-stage liver diseases and acute liver failure (ALF). Due to several limitations, stem-cell-based therapies are currently being developed as alternative solutions. …”
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“…Among the 118 LD patients, 6 (5.1%) were ALF patients, 32 (27.1%) were ACLF patients, 66 (55.9%) were CLD patients and 14 (11.9%) were post-LT patients. …”
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“…%CaF(2), 10.0 wt.%Na(3)AlF(6)) has a melting point (562.2 °C) below the refining temperature. …”
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“…HF etching is problematic because it leaves insoluble AlF(3) in the product, degrades the crystallinity of the nanosheets, and results in the termination of the basal planes with F, O, or OH groups. …”
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“…This dissociation was inhibited by AlF4-, suggesting trimeric G proteins are involved in the dissociation mechanism. …”
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“…Sey1p forms a side-by-side dimer in complex with GMP-PNP or GDP/AlF(4)(−) but is monomeric with GDP. Surprisingly, Sey1p could mediate fusion without GTP hydrolysis, even though fusion was much more efficient with GTP. …”
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“…Human umbilical cord-derived mesenchymal stem cells (UCMSCs) are particularly attractive cells for cellular and gene therapy in acute liver failure (ALF). However, the efficacy of this cell therapy in animal studies needs to be significantly improved before it can be translated into clinics. …”
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“…This data set is composed of transcriptomics analyses of (i) liver samples from patients suffering from acetaminophen-induced acute liver failure (ALF) and (ii) hepatic cell systems exposed to acetaminophen and their respective controls. …”
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“…Acetaminophen (APAP), a commonly used over-the-counter analgesic, accounts for approximately fifty percent of the cases of acute liver failure (ALF) in the United States due to overdose, with over half of those unintentional. …”
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“…The clinical course of these infections differs: genotype 1 and 2 infection can cause acute illness and can lead to acute liver failure (ALF) or acute on chronic liver failure (ACLF) with a high mortality rate of 20% in pregnant women. …”
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“…The AVF1/ISR DNA marker for A. villosum produced a 270 bases amplified product, while the ALF1/ISF DNA marker produced a 350 bases product specific for A. longiligulare. …”
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