Mostrando 61 - 80 Resultados de 3,173 Para Buscar '"ALMS"', tiempo de consulta: 0.22s Limitar resultados
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  5. 65
    Publicado 2004
    Libro
  6. 66
    Publicado 1994
    Libro
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  8. 68
    Publicado 1988
    Libro
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  10. 70
    por Matteo, da Perugia, d. ca. 1418
    Publicado 1998
    Tabla de Contenidos:
    CD Audiom
  11. 71
    “…BACKGROUND: Alström syndrome (AS), featuring retinal dystrophy, neuronal deafness, cardiomyopathy, metabolic syndrome, and diffuse fibrosis, is caused by biallelic mutations in the centrosomal protein ALMS1. Genotype–phenotype correlation has been suggested without assessment of ALMS1 expression. …”
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  14. 74
    “…BACKGROUND: Alström syndrome (AS) is a rare autosomal recessive disease that is generally induced by mutations of the Alström syndrome 1 (ALMS1) gene. We report a case of AS, extend the spectrum of ALMS1 mutations and highlight the biological role of ALMS1 to explore the relationship between dilated cardiomyopathy (DCM) and mutations in ALMS1. …”
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  15. 75
    “…We have developed a method to generate alveolar-like macrophages (ALMs) from pluripotent stem cells. These ALMs have shown potential to promote airway innate immunity and tissue repair and so we hypothesized that ALMs could be used as a strategy to prevent RSV infection. …”
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  16. 76
    “…Comprehensive analyses on the behaviors of the ALMS loop have been published in the literature. …”
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  17. 77
    “…Early emergence of obesity in patients with AS suggests a key role for ALMS1 in body weight regulation. Mice with non-functional Alms1 develop normal hypothalamic cilia, but these are not maintained postnatally. …”
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  18. 78
    “…We have shown a relative AT failure in a monogenic obese cohort, a finding supported by observations in a novel conditional mouse model (Alms(flin/flin)) and ALMS1-silenced human primary adipocytes, whereas selective reactivation of ALMS1 gene in AT of an ALMS conditional knockdown mouse model (Alms(flin/flin); Adipo-Cre(+/−)) restores systemic insulin sensitivity and glucose tolerance. …”
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  19. 79
    “…Clinical parameters including lipids profile, serum creatinine, cystatin C, fasting glucose, insulin and C-peptide levels, HbA1c values and insulin resistance (HOMA-IR) were assessed in patients with ALMS and BBS. RESULTS: We observed multiple up- or downregulated miRNAs in both ALMS and BBS patients compared to obese patients and controls, but only 1 miRNA (miR-301a-3p) differed significantly and in the same direction in ALMS and BBS relative to the other groups. …”
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  20. 80
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