por
Nagahara, Keiko,
Nishibukuro, Tsuyoshi,
Ogiwara, Yasuko,
Ikegawa, Kento,
Tada, Hayato,
Yamagishi, Masakazu,
Kawashiri, Masa-aki,
Ochi, Ayako,
Toyoda, Junya,
Nakano, Yuya,
Adachi, Masanori,
Mizuno, Katsumi,
Hasegawa, Yukihiro,
Dobashi, Kazushige
Publicado 2022
“…Among 17 patients without FH causative gene variants, 3 children had variants in LDL-altering genes,
anAPOE variant and twoABCG8 variants. The mean serum total cholesterol (280 vs 246 mg/dL), LDL-cholesterol (LDL-C, 217 vs 177 mg/dL), and non-HDL cholesterol (228 vs 188 mg/dL) levels were significantly higher in the pathogenic variant-positive group than in the variant-negative group. …”
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