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2701por Moutsopoulos, Haralampos M.“…Autoimmune and autoinflammatory rheumatic disorders (ARD) are treated with antimetabolites, calcineurin inhibitors and biologic agents either neutralizing cytokines [Tumor Necrosis Factor (TNF), Interleukin (IL)-1, IL-6, IL-17, B-cell activating factor] or being directed against B-cells (anti-CD-20), costimulatory molecules or JAK kinases. …”
Publicado 2021
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2702
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2703“…We characterize the broad innate immune responses to Coccidioides by analyzing macrophage and dendritic cell responses to Coccidioides arthroconidia using avirulent, vaccine Coccidioides strain NR-166 (Δcts2/Δard1/Δcts3), developed from parental virulent strain C735. …”
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2704“…These carotenoids are concentrated by the action of specific binding proteins such as StARD3, which binds lutein, and GSTP1, which binds zeaxanthin and its dietary metabolite, mesozeaxanthin. …”
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2705
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2706
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2707“…Two SNAT candidate genes, from Methanoregulaceae (Archaea) and Pyrococcus furiosus, showed no SNAT enzyme activity, whereas a SNAT candidate gene from Thermoplasma volcanium previously named TvArd1 exhibited SNAT enzyme activity. The substrate affinity and the maximum reaction rate of TvSNAT toward serotonin were 621 μM and 416 pmol/min/mg protein, respectively. …”
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2708por Mirelli, Cristina, Marino, Sonia, Bovio, Andrea, Pederielli, Sara, Dall’Agnola, Cristina, Gianni, Aldo Bruno, Biagi, Roberto“…A retrospective analysis was performed with the aim of understanding whether the risk factors showed in the literature for medication-related osteonecrosis of the jaws (MRONJ) in cancer patients are also relevant in osteoporotic patients taking antiresorptive drugs (ARDs). Data were retrospectively pooled from health records of patients on ARDs who requested a dental visit between January 2006 and April 2020 in the Dental Unit at Fondazione Ca’ Granda IRCCS Ospedale Maggiore Policlinico, University of Milan. …”
Publicado 2022
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2709“…We have previously derived power calculation formulas for cohort studies and clinical trials using the longitudinal mixed effects model with random slopes and intercepts to compare rate of change across groups [Ard & Edland, Power calculations for clinical trials in Alzheimer’s disease. …”
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2711Publicado 2021“…In the anakinra group, 21 (36%) of 59 patients had a WHO-CPS score of more than 5 at day 4 versus 21 (38%) of 55 in the usual care group (median posterior absolute risk difference [ARD] −2·5%, 90% credible interval [CrI] −17·1 to 12·0), with a posterior probability of ARD of less than 0 (ie, anakinra better than usual care) of 61·2%. …”
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2712por Spencer, John“…In collider experiments, very light particles are produced in the far-forward direction with small angle relative to the beam axis and can travel a long distance before decaying. The ForwArd Search ExpeRiment (FASER) is aptly located 480 m downstream from the ATLAS interaction point where background is minimal, so optimally positioned to detect very light new particles. …”
Publicado 2022
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2713
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2714
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2715por Wedderburn, Lucy R, Ramanan, Athimalaipet V, Croft, Adam P, Hyrich, Kimme L, Dick, Andrew DEnlace del recurso
Publicado 2023
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2717
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2718
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2719
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2720por Koike, Takao, Harigai, Masayoshi, Inokuma, Shigeko, Ishiguro, Naoki, Ryu, Junnosuke, Takeuchi, Tsutomu, Takei, Syuji, Tanaka, Yoshiya, Ito, Kyoko, Yamanaka, HisashiEnlace del recurso
Publicado 2011
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