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284“…Inhaled volatile agents may also provide important pulmonary benefits for COVID-19 patients with ARDS that could improve gas exchange and reduce time spent on a ventilator. …”
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285por Xu, Lili, Liu, Jun, Pang, Yilin, Guan, Xiaolei, Qian, Suyun, Xie, Zhengde, Gao, HengmiaoEnlace del recurso
Publicado 2018
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286por Rilinger, Jonathan, Zotzmann, Viviane, Bemtgen, Xavier, Schumacher, Carin, Biever, Paul M., Duerschmied, Daniel, Kaier, Klaus, Stachon, Peter, von zur Mühlen, Constantin, Zehender, Manfred, Bode, Christoph, Staudacher, Dawid L., Wengenmayer, Tobias“…BACKGROUND: Prone positioning (PP) has shown to improve survival in patients with severe acute respiratory distress syndrome (ARDS). To this point, it is unclear if PP is also beneficial for ARDS patients treated with veno-venous extracorporeal membrane oxygenation (VV ECMO) support. …”
Publicado 2020
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287por Kreitmann, Louis, Monard, Céline, Dauwalder, Olivier, Simon, Marie, Argaud, LaurentEnlace del recurso
Publicado 2020
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288“…Severe pediatric ARDS remains a significant challenge for clinicians, and management strategies are essentially limited to lung protective ventilation strategies, and adjunct approaches such as prone positioning, steroids, surfactant, and inhaled nitric oxide in unique situations. …”
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289“…In this review we connect the current understanding of the SARS-CoV-2 replication cycle and host response to the clinical presentation of COVID-19, borrowing concepts from influenza A virus-induced ARDS pathogenesis and discussing how these ideas inform our evolving understanding of COVID-19-induced ARDS. …”
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291por Mezidi, Mehdi, Daviet, Florence, Chabert, Paul, Hraiech, Sami, Bitker, Laurent, Forel, Jean-Marie, Yonis, Hodane, Gragueb, Ines, Dhelft, Francois, Papazian, Laurent, Richard, Jean-Christophe, Guervilly, Christophe“…BACKGROUND: Data on respiratory mechanics of COVID-19 ARDS patients are scarce. Respiratory mechanics and response to positive expiratory pressure (PEEP) may be different in obese and non-obese patients. …”
Publicado 2020
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293por Mittermaier, Mirja, Pickerodt, Philipp, Kurth, Florian, de Jarcy, Laure Bosquillon, Uhrig, Alexander, Garcia, Carmen, Machleidt, Felix, Pergantis, Panagiotis, Weber, Susanne, Li, Yaosi, Breitbart, Astrid, Bremer, Felix, Knape, Philipp, Dewey, Marc, Doellinger, Felix, Weber-Carstens, Steffen, Slutsky, Arthur S., Kuebler, Wolfgang M., Suttorp, Norbert, Müller-Redetzky, Holger“…BACKGROUND: In face of the Coronavirus Disease (COVID)-19 pandemic, best practice for mechanical ventilation in COVID-19 associated Acute Respiratory Distress Syndrome (ARDS) is intensely debated. Specifically, the rationale for high positive end-expiratory pressure (PEEP) and prone positioning in early COVID-19 ARDS has been questioned. …”
Publicado 2020
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294por Kapp, Chris, Or, Esther Ben, Thiboutot, Jeffrey, Bhatti, Nasir, Haut, Elliott, Stokes, Jacqueline, Lester, Laeben, Yarmus, Lonny, Lee, Hans, Hillel, Alexander, Feller-Kopman, DavidEnlace del recurso
Publicado 2020
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296por Ronit, Andreas, Berg, Ronan M.G., Bay, Jakob T., Haugaard, Anna K., Ahlström, Magnus G., Burgdorf, Kristoffer S., Ullum, Henrik, Rørvig, Sara B., Tjelle, Klaus, Foss, Nicolai B., Benfield, Thomas, Marquart, Hanne Vibeke, Plovsing, Ronni R.“…RESULTS: Four mechanically ventilated patients (aged 40-75 years) with moderate-to-severe COVID-19 ARDS were included. Immature neutrophils dominated in both blood and lungs, whereas CD4 and CD8 T-cell lymphopenia was observed in the 2 compartments. …”
Publicado 2021
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297por Alhazzani, Waleed, Belley-Cote, E., Møller, M. H., Angus, D. C., Papazian, L., Arabi, Y. M., Citerio, G., Connolly, B., Denehy, L., Fox-Robichaud, A., Hough, C. L., Laake, J. H., Machado, F. R., Ostermann, M., Piraino, T., Sharif, S., Szczeklik, W., Young, P. J., Gouskos, A., Kiedrowski, K., Burns, K. E. A.“…The ICM-RPG panel issued one recommendation and two suggestions regarding the use of NMBAs in adults with ARDS. Current evidence does not support the early routine use of an NMBA infusion in adults with ARDS of any severity. …”
Publicado 2020
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298“…With the exception of a few successes in trials of supportive care, the majority of interventional clinical trials for acute respiratory distress syndrome (ARDS) have not led to new therapies. To improve the likelihood of benefit from clinical trial interventions in ARDS, clinical trial design must be improved. …”
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299por Li, Zhongwen, Niu, Shuaishuai, Guo, Baojie, Gao, Tingting, Wang, Lei, Wang, Yukai, Wang, Liu, Tan, Yuanqing, Wu, Jun, Hao, Jie“…MSCs have been suggested to ameliorate the cytokine release syndrome (CRS) and protect alveolar epithelial cells by secreting many kinds of factors, demonstrating safety and possible efficacy in COVID‐19 patients with acute respiratory distress syndrome (ARDS). However, considering the consistency and uniformity of stem cell quality cannot be quantified nor guaranteed at this point, more work remains to be done in the future.…”
Publicado 2020
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300por Guérin, Claude, Albert, Richard K., Beitler, Jeremy, Gattinoni, Luciano, Jaber, Samir, Marini, John J., Munshi, Laveena, Papazian, Laurent, Pesenti, Antonio, Vieillard-Baron, Antoine, Mancebo, Jordi“…In ARDS patients, the change from supine to prone position generates a more even distribution of the gas–tissue ratios along the dependent–nondependent axis and a more homogeneous distribution of lung stress and strain. …”
Publicado 2020
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