EULAR study group on ‘MHC-I-opathy’: identifying disease-overarching mechanisms across disciplines and borders

por Kuiper, Jonas JW, Prinz, Jörg C, Stratikos, Efstratios, Kuśnierczyk, Piotr, Arakawa, Akiko, Springer, Sebastian, Mintoff, Dillon, Padjen, Ivan, Shumnalieva, Russka, Vural, Seçil, Kötter, Ina, van de Sande, Marleen G, Boyvat, Ayşe, de Boer, Joke H, Bertsias, George, de Vries, Niek, Krieckaert, Charlotte LM, Leal, Inês, Vidovič Valentinčič, Nataša, Tugal-Tutkun, Ilknur, el Khaldi Ahanach, Hanane, Costantino, Félicie, Glatigny, Simon, Mrazovac Zimak, Danijela, Lötscher, Fabian, Kerstens, Floor G, Bakula, Marija, Viera Sousa, Elsa, Böhm, Peter, Bosman, Kees, Kenna, Tony J, Powis, Simon J, Breban, Maxime, Gul, Ahmet, Bowes, John, Lories, Rik JU, Nowatzky, Johannes, Wolbink, Gerrit Jan, McGonagle, Dennis G, Turkstra, Franktien
Publicado 2023

Immunomics analysis of rheumatoid arthritis identified precursor dendritic cells as a key cell subset of treatment resistance

por Yamada, Saeko, Nagafuchi, Yasuo, Wang, Min, Ota, Mineto, Hatano, Hiroaki, Takeshima, Yusuke, Okubo, Mai, Kobayashi, Satomi, Sugimori, Yusuke, Masahiro, Nakano, Yoshida, Ryochi, Hanata, Norio, Suwa, Yuichi, Tsuchida, Yumi, Iwasaki, Yukiko, Sumitomo, Shuji, Kubo, Kanae, Shimane, Kenichi, Setoguchi, Keigo, Azuma, Takanori, Kanda, Hiroko, Shoda, Hirofumi, Zhang, Xuan, Yamamoto, Kazuhiko, Ishigaki, Kazuyoshi, Okamura, Tomohisa, Fujio, Keishi
Publicado 2023

Identification of new risk loci shared across systemic vasculitides points towards potential target genes for drug repurposing

por Ortiz-Fernández, Lourdes, Carmona, Elio G, Kerick, Martin, Lyons, Paul, Carmona, Francisco David, López Mejías, Raquel, Khor, Chiea Chuen, Grayson, Peter C, Tombetti, Enrico, Jiang, Lindi, Direskeneli, Haner, Saruhan-Direskeneli, Guher, Callejas-Rubio, José-Luis, Vaglio, Augusto, Salvarani, Carlo, Hernández-Rodríguez, Jose, Cid, Maria Cinta, Morgan, Ann W, Merkel, Peter A, Burgner, David, Smith, Kenneth GC, Gonzalez-Gay, Miguel Angel, Sawalha, Amr H, Martin, Javier, Marquez, Ana
Publicado 2023

Cancer risks with JAKi and biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis or psoriatic arthritis: a national real-world cohort study

por Huss, Viking, Bower, Hannah, Hellgren, Karin, Frisell, Thomas, Askling, Johan
Publicado 2023

Towards development of treat to target (T2T) in childhood-onset systemic lupus erythematosus: PReS-endorsed overarching principles and points-to-consider from an international task...

por Smith, Eve Mary Dorothy, Aggarwal, Amita, Ainsworth, Jenny, Al-Abadi, Eslam, Avcin, Tadej, Bortey, Lynette, Burnham, Jon, Ciurtin, Coziana, Hedrich, Christian M, Kamphuis, Sylvia, Levy, Deborah M, Lewandowski, Laura B, Maxwell, Naomi, Morand, Eric F, Ozen, Seza, Pain, Clare E, Ravelli, Angelo, Saad Magalhaes, Claudia, Pilkington, Clarissa A, Schonenberg-Meinema, Dieneke, Scott, Christiaan, Tullus, Kjell, Beresford, Michael William
Publicado 2023

Increased risk of osteoarthritis in patients with atopic disease

por Baker, Matthew C, Sheth, Khushboo, Lu, Rong, Lu, Di, von Kaeppler, Ericka P, Bhat, Archana, Felson, David T, Robinson, William H
Publicado 2023

Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis

por Matsuoka, Kazuhiko, Bakiri, Latifa, Bilban, Martin, Toegel, Stefan, Haschemi, Arvand, Yuan, Hao, Kasper, Maria, Windhager, Reinhard, Wagner, Erwin F
Publicado 2023

Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares

por Azzouz, Doua F, Chen, Ze, Izmirly, Peter M, Chen, Lea Ann, Li, Zhi, Zhang, Chongda, Mieles, David, Trujillo, Kate, Heguy, Adriana, Pironti, Alejandro, Putzel, Greg G, Schwudke, Dominik, Fenyo, David, Buyon, Jill P, Alekseyenko, Alexander V, Gisch, Nicolas, Silverman, Gregg J
Publicado 2023

Accuracy and impact on quality of life of real-time continuous glucose monitoring in children with hyperinsulinaemic hypoglycaemia

por Sivasubramanian, Madhini, Avari, Parizad, Gilbert, Clare, Doodson, Louise, Morgan, Kate, Oliver, Nick, Shah, Pratik
Publicado 2023

Cartilage-specific Sirt6 deficiency represses IGF-1 and enhances osteoarthritis severity in mice

por Collins, John A, Kim, C James, Coleman, Ashley, Little, Abreah, Perez, Matheus M, Clarke, Emily J, Diekman, Brian, Peffers, Mandy J, Chubinskaya, Susanna, Tomlinson, Ryan E, Freeman, Theresa A, Loeser, Richard F
Publicado 2023

Effect of tapered versus stable treatment with tumour necrosis factor inhibitors on disease flares in patients with rheumatoid arthritis in remission: a randomised, open label, non...

por Lillegraven, Siri, Paulshus Sundlisæter, Nina, Aga, Anna-Birgitte, Sexton, Joseph, Olsen, Inge Christoffer, Lexberg, Åse Stavland, Madland, Tor Magne, Fremstad, Hallvard, Høili, Christian A., Bakland, Gunnstein, Spada, Cristina, Haukeland, Hilde, Hansen, Inger Myrnes, Moholt, Ellen, Uhlig, Till, Solomon, Daniel H, van der Heijde, Désirée, Kvien, Tore K, Haavardsholm, Espen A
Publicado 2023

New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function

por Saviano, Anella, Manosour, Adel Abo, Raucci, Federica, Merlino, Francesco, Marigliano, Noemi, Schettino, Anna, Wahid, Mussarat, Begum, Jenefa, Filer, Andrew, Manning, Julia E, Casillo, Gian Marco, Piccolo, Marialuisa, Ferraro, Maria Grazia, Marzano, Simona, Russomanno, Pasquale, Bellavita, Rosa, Irace, Carlo, Amato, Jussara, Alfaifi, Mohammed, Rimmer, Peter, Iqbal, Tariq, Pieretti, Stefano, Vellecco, Valentina, Caso, Francesco, Costa, Luisa, Giacomelli, Roberto, Scarpa, Raffaele, Cirino, Giuseppe, Bucci, Mariarosaria, McGettrick, Helen M, Grieco, Paolo, Iqbal, Asif Jilani, Maione, Francesco
Publicado 2023

Anti-GM-CSF otilimab versus sarilumab or placebo in patients with rheumatoid arthritis and inadequate response to targeted therapies: a phase III randomised trial (contRAst 3)

por Taylor, Peter C, Weinblatt, Michael E, McInnes, Iain B, Atsumi, Tatsuya, Strand, Vibeke, Takeuchi, Tsutomu, Bracher, Marguerite, Brooks, David, Davies, John, Goode, Christopher, Gupta, Anubha, Mukherjee, Sumanta, O’Shea, Ciara, Saurigny, Didier, Schifano, Lorrie A, Shelton, Celia, Smith, Julia E, Wang, Millie, Wang, Reena, Watts, Sarah, Fleischmann, Roy M
Publicado 2023

Disease activity drives transcriptomic heterogeneity in early untreated rheumatoid synovitis

por Triaille, Clément, Tilman, Gaëlle, Sokolova, Tatiana, Loriot, Axelle, Marchandise, Joelle, De Montjoye, Stéphanie, Nzeusseu-Toukap, Adrien, Méric de Bellefon, Laurent, Bouzin, Caroline, Galant, Christine, Durez, Patrick, Lauwerys, Bernard R, Limaye, Nisha
Publicado 2023

Ovarian dysfunction in adolescent girls with autoimmune rheumatic diseases

por Taman, Mohamed, NM, El-Hadidy, Yousef, Hamed, Mosa, Doaa Mosad
Publicado 2023

Can clinical factors at presentation be used to predict outcome of treatment with methotrexate in patients with early inflammatory polyarthritis?

por Hider, S L, Silman, A J, Thomson, W, Lunt, M, Bunn, D, Symmons, D P M
Publicado 2009

Rates of new-onset psoriasis in patients with rheumatoid arthritis receiving anti-tumour necrosis factor α therapy: results from the British Society for Rheumatology Biologics Regi...

por Harrison, M J, Dixon, W G, Watson, K D, King, Y, Groves, R, Hyrich, K L, Symmons, D P M
Publicado 2008

Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patien...

por Wells, G, Becker, J-C, Teng, J, Dougados, M, Schiff, M, Smolen, J, Aletaha, D, van Riel, P L C M
Publicado 2008

Golimumab, a human antibody to tumour necrosis factor α given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study

por Keystone, E C, Genovese, M C, Klareskog, L, Hsia, E C, Hall, S T, Miranda, P C, Pazdur, J, Bae, S-C, Palmer, W, Zrubek, J, Wiekowski, M, Visvanathan, S, Wu, Z, Rahman, M U
Publicado 2008

Adalimumab effectiveness for the treatment of ankylosing spondylitis is maintained for up to 2 years: long-term results from the ATLAS trial

por van der Heijde, D, Schiff, M H, Sieper, J, Kivitz, A J, Wong, R L, Kupper, H, Dijkmans, B A C, Mease, P J, Davis, J C
Publicado 2008