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4841por Hong, Shukun, Jian, Chao, Wang, Hongye, Wang, Xincheng, Xing, Luchuan, Qiao, Lujun“…BACKGROUND: The optimal dose of glucocorticoids for acute respiratory distress syndrome (ARDS) is uncertain. This study aimed to evaluate the effects of different doses of methylprednisolone on sepsis-induced acute lung injury (ALI) rats and a cohort of moderate and severe ARDS patients. …”
Publicado 2022
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4842por Niu, Zhifang, Ding, Ziling, Chan, Yion, Yan, Li, Zhang, Wenyu, Wang, Hongyu, Shi, Jie, Lv, Qi, Hou, Shike, Guo, Xiaoqin, Fan, Haojun“…Lactic acid >9.60 (mmol/l) demonstrated a high degree of accuracy in predicting ARDS development in patients with SII. Hemoglobin <83.00 (g/l) showed a high degree of accuracy in predicting mortality. …”
Publicado 2022
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4843por Lee, Hyun Woo, Yang, Hyun Jun, Kim, Hyungjin, Kim, Ue-Hwan, Kim, Dong Hyun, Yoon, Soon Ho, Ham, Soo-Youn, Nam, Bo Da, Chae, Kum Ju, Lee, Dabee, Yoo, Jin Young, Bak, So Hyeon, Kim, Jin Young, Kim, Jin Hwan, Kim, Ki Beom, Jung, Jung Im, Lim, Jae-Kwang, Lee, Jong Eun, Chung, Myung Jin, Lee, Young Kyung, Kim, Young Seon, Lee, Sang Min, Kwon, Woocheol, Park, Chang Min, Kim, Yun-Hyeon, Jeong, Yeon Joo, Jin, Kwang Nam, Goo, Jin Mo“…Both the AI and combined models showed good calibration for predicting ARDS (P=.079 and P=.859). CONCLUSIONS: The combined prediction model, comprising the CXR score and clinical information, was externally validated as having acceptable performance in predicting severe illness and excellent performance in predicting ARDS in patients with COVID-19.…”
Publicado 2023
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4844por Chiumello, Davide, Brochard, Laurent, Marini, John J., Slutsky, Arthur S., Mancebo, Jordi, Ranieri, V. Marco, Thompson, B. Taylor, Papazian, Laurent, Schultz, Marcus J., Amato, Marcelo, Gattinoni, Luciano, Mercat, Alain, Pesenti, Antonio, Talmor, Daniel, Vincent, Jean-Louis“…Acute respiratory distress syndrome (ARDS) is a common condition in intensive care unit patients and remains a major concern, with mortality rates of around 30–45% and considerable long-term morbidity. …”
Publicado 2017
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4845“…The most common symptom of COVID-19 in critically ill patients is ARDS (acute respiratory distress syndrome), with many patients requiring invasive or noninvasive respiratory support in the intensive care unit. …”
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4846“…The clinical management of severely ill patients with COVID-19-related acute respiratory distress syndrome (ARDS) presents significant challenges. Many COVID-19 patients with ARDS also present with laboratory findings significant for derangement in coagulation function. …”
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4847por Yuan, Hao-Xiang, Chen, Ya-Ting, Li, Yu-Quan, Wang, Yan-Sheng, Ou, Zhi-Jun, Li, Yan, Gao, Jian-Jun, Deng, Meng-Jie, Song, Yuan-Kai, Fu, Li, Ci, Hong-Bo, Chang, Feng-Jun, Cao, Yang, Jian, Yu-Peng, Kang, Bi-Ang, Mo, Zhi-Wei, Ning, Da-Sheng, Peng, Yue-Ming, Liu, Ze-Long, Liu, Xiao-Jun, Xu, Ying-Qi, Xu, Jun, Ou, Jing-Song“…ALI could be attenuated by JAK2/3 or STAT3 inhibitors (AG490 or S3I-201, respectively), and was relieved in TLR4(−/−) and iNOS(−/−) mice. eEVs activate the TLR4/JAK3/STAT3/IRF-1 signaling pathway to induce ALI/ARDS by delivering follistatin-like protein 1 (FSTL1), and FSTL1 knockdown in eEVs alleviates eEV-induced ALI/ARDS. …”
Publicado 2023
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4848por Wu, Yanqi, Wang, Yahui, Liu, Bo, Cheng, Yumei, Qian, Hong, Yang, Huilin, Li, Xiang, Yang, Guixia, Zheng, Xinghao, Shen, Feng“…BACKGROUND: It has been confirmed that NF-κB p65 signaling pathway is involved in the regulation of alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome (ARDS). Whether SN50, a NF-κB cell permeable inhibitor, could attenuate alveolar hypercoagulation and fibrinolysis inhibition in ARDS remains to be elucidated. …”
Publicado 2020
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4849por Schroeder, Ines, Scharf, Christina, Zoller, Michael, Wassilowsky, Dietmar, Frank, Sandra, Stecher, Stephanie-Susanne, Stemmler, Joachim, Kneidinger, Nikolaus, Peterß, Sven, Zwißler, Bernhard, Irlbeck, Michael“…Of the patients 27.1% were transferred to the LMU hospital from external hospitals with reference to our ARDS/ECMO program. Patients from external hospitals had ARDS of higher severity than the total study population. …”
Publicado 2020
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4850por Trigonis, Russell, Smith, Nikki, Porter, Shelley, Anderson, Eve, Jennings, Mckenna, Kapoor, Rajat, Hage, Chadi, Moiz, Salwa, Garcia, Jose, Rahman, Omar“…The authors set out to compare the pharmacologic characteristics and dosing requirements of bivalirudin in patients requiring ECMO support for ARDS due to COVID-19 versus ARDS from other etiologies. …”
Publicado 2022
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4851por Chang, Hui-Chun, Ho, Chung-Han, Kung, Shu-Chen, Chen, Wan-Lin, Wang, Ching-Min, Cheng, Kuo-Chen, Liu, Wei-Lun, Hsu, Han-Shui“…BACKGROUND: Driving pressure (∆P) is an important factor that predicts mortality in acute respiratory distress syndrome (ARDS). We test the hypothesis that serial changes in daily ΔP rather than Day 1 ΔP would better predict outcomes of patients with ARDS. …”
Publicado 2021
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4852por Le Pape, Marc, Besnard, Céline, Acatrinei, Camelia, Guinard, Jérôme, Boutrot, Maxime, Genève, Claire, Boulain, Thierry, Barbier, François“…BACKGROUND: The clinical impact and outcomes of ventilator-associated pneumonia (VAP) have been scarcely investigated in patients with the acute respiratory distress syndrome (ARDS). METHODS: Patients admitted over an 18-month period in two intensive care units (ICU) of a university-affiliated hospital and meeting the Berlin criteria for ARDS were retrospectively included. …”
Publicado 2022
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4853por Boesing, Christoph, Graf, Peter T., Schmitt, Fabian, Thiel, Manfred, Pelosi, Paolo, Rocco, Patricia R. M., Luecke, Thomas, Krebs, Joerg“…CONCLUSIONS: Prone positioning increased transpulmonary pressures while improving oxygenation and hemodynamics in patients with moderate to severe ARDS when PEEP was titrated according to the ARDS Network lower PEEP table. …”
Publicado 2022
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4854por Wang, Ke, Wang, Youyu, Cao, Yufang, Wang, Hao, Zhou, Yongfang, Gao, Lijuan, Zeng, Zijian, Cheng, Mengxin, Jin, Xiaodong, Chen, Jun, Wen, Fuqiang, Wang, Tao“…BACKGROUND: Fibroproliferative repair starts early in the inflammatory phase of acute respiratory distress syndrome (ARDS) and indicates a poor prognosis. Lumican, a small leucine-rich proteoglycan, is implicated in homeostasis and fibrogenesis, but its role in ARDS is unclear. …”
Publicado 2022
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4855por Perez, Jesus A, Parcero Valdes, Juan J, Corral Moreno, Ruben, Gomez Cuevas, Leonardo I, Lopez, Jose J, Ichim, Thomas, McGreevy, Kristen, Lin, Feng, Kesari, Santosh, Datta, Souvik“…The COVID-19 pandemic has posed significant therapeutic challenges in addressing acute respiratory distress syndrome (ARDS). This serious illness has caused numerous fatalities worldwide and has had profound health and economic impacts. …”
Publicado 2023
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4856“…Therapeutic mechanisms of MSCs in the treatment of ARDS/COPD were focused on cell engraftment and paracrine action. …”
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4857por Ingelse, Sarah A., Wösten-van Asperen, Roelie M., Lemson, Joris, Daams, Joost G., Bem, Reinout A., van Woensel, Job B.“…Indeed, studies in adults with ARDS have shown that an increased cumulative fluid balance is associated with adverse outcome. …”
Publicado 2016
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4858por Bharara, Amit, Grossman, Catherine, Grinnan, Daniel, Syed, Aamer, Fisher, Bernard, DeWilde, Christine, Natarajan, Ramesh, Fowler, Alpha A. (Berry)“…This case report summarizes the first use of intravenous vitamin C employed as an adjunctive interventional agent in the therapy of recurrent acute respiratory distress syndrome (ARDS). The two episodes of ARDS occurred in a young female patient with Cronkhite-Canada syndrome, a rare, sporadically occurring, noninherited disorder that is characterized by extensive gastrointestinal polyposis and malabsorption. …”
Publicado 2016
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4859“…Acute respiratory distress syndrome (ARDS), characterized by hypoxemic respiratory failure, is associated with a mortality of 30–50% and is precipitated by both direct and indirect pulmonary insults. …”
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4860“…Acute respiratory distress syndrome (ARDS) mainly involves acute respiratory failure. …”
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