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6421Small molecule inhibitor CRT0066101 inhibits cytokine storm syndrome in a mouse model of lung injury“…However, there are currently no effective treatments for inflammatory cytokine storms in patients with ALI/acute respiratory distress syndrome (ARDS). Protein kinase D (PKD) is a highly active kinase that has been shown to be associated with the production of inflammatory cytokines. …”
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6422por Wu, Yuxuan, Sun, Hao, Qin, Lianju, Zhang, Xiaomin, Zhou, Hao, Wang, Yao, Wang, Lumin, Li, Meng, Liu, Jiayin, Zhang, Jinsong“…Acute lung injury (ALI) is one of the most common clinical emergencies with limited effective pharmaceutical treatment in the clinic, especially when it progresses to acute respiratory distress syndrome (ARDS). Currently, mesenchymal stem cells (MSCs) exhibit specific superiority for ALI/ARDS treatment. …”
Publicado 2023
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6423por Oliynyk, Oleksandr Valentynovych, Rorat, Marta, Solyarik, Serhij Oleksandrovych, Lukianchuk, Vitaliy Andrijovych, Dubrov, Serhij Oleksandrovych, Guryanov, Vitaliy Hrygorovych, Oliynyk, Yanina Volodymyrivna, Yaroslavskaya, Svitlana Mykolaivna, Szalast, Roman, Barg, Wojciech“…A retrospective study analyzed 74 patients with PE and acute respiratory distress syndrome (ARDS) due to COVID-19 who were hospitalized in the intensive care unit in 2021. …”
Publicado 2023
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6424por Taccone, Fabio Silvio, Rinaldi, Simone, Annoni, Filippo, Nobile, Leda, Di Nardo, Matteo, Maccieri, Jessica, Aliberti, Anna, Malfertheiner, Maximilan Valentin, Marudi, Andrea, Broman, Lars Mikael, Belliato, Mirko“…Methods: Adult patients on mechanical ventilation due to acute respiratory distress syndrome (ARDS) or decompensated chronic obstructive pulmonary disease (dCOPD), who were treated with a dedicated ECCO(2)R device (CO2RESET, Eurosets, Medolla, Italy) in case of hypercapnic acidemia, were included. …”
Publicado 2023
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6425por López-García, Aura Angélica, Ramos-Choreño, Miguel Ángel, Sánchez-Hurtado, Luis Alejandro, Romero-Gutiérrez, Laura, Calleja-Alarcón, Salvador, Gudiño-Turrubiates, Araceli, Neri-Muñoz, Natividad, Ponce-Sánchez, Jesús Manuel, Colín-Martínez, Tania“…The most severe form is acute respiratory distress syndrome (ARDS). The inflammatory response can cause hematologic changes. …”
Publicado 2023
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6426“…Dysfunction of PS contributes to various respiratory diseases, including neonatal respiratory distress syndrome (NRDS), adult respiratory distress syndrome (ARDS), COVID-19-associated ARDS, and ventilator-induced lung injury (VILI), among others. …”
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6427por Arora, Mehak, Davis, Carolyn M., Gowda, Niraj R., Foster, Dennis G., Mondal, Angana, Coopersmith, Craig M., Kamaleswaran, Rishikesan“…Acute Respiratory Distress Syndrome (ARDS) is a severe lung injury with high mortality, primarily characterized by bilateral pulmonary opacities on chest radiographs and hypoxemia. …”
Publicado 2023
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6428“…The aim of this research was to determine the anti-inflammatory effect of betaine on sepsis-induced acute respiratory distress syndrome (ARDS) in rats through histopathological examination, radiologic imaging, and biochemical analysis. …”
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6429“…The current study was aimed to compare two recruitment maneuvers, a high continuous positive airway pressure (CPAP), and an extended sigh in patients with ARDS. MATERIALS AND METHODS: Forty patients with acute respiratory distress syndrome were randomly divided into two groups, 20 patients each. …”
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6430por Auner, Birgit, Geiger, Emanuel V., Henrich, Dirk, Lehnert, Mark, Marzi, Ingo, Relja, Borna“…Thirty patients developed PC (pneumonia, respiratory failure, acute lung injury (ALI), ARDS, pulmonary embolism) and 70 had no PC (ØPC). …”
Publicado 2012
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6431“…OBJECTIVE: To compare quantitative computed tomography (CT) analysis and single-indicator thermodilution to measure pulmonary edema in patients with acute respiratory distress syndrome (ARDS). METHOD: Ten patients with ARDS were included. …”
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6432por Lingappan, Krithika, Srinivasan, Chandra, Jiang, Weiwu, Wang, Lihua, Couroucli, Xanthi I., Moorthy, Bhagavatula“…Exposure to high concentration of oxygen (hyperoxia) leads to lung injury in experimental animal models and plays a role in the pathogenesis of diseases such as Acute Respiratory Distress Syndrome (ARDS) and Bronchopulmonary dysplasia (BPD) in humans. …”
Publicado 2014
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6433“…BACKGROUND: Microvesicles (MV) have been implicated in the development of thrombotic disease, such as acute respiratory distress syndrome (ARDS) and multiple organ failure (MOF). Trauma patients are at increased risk of late thrombotic events, particularly those who receive a major transfusion. …”
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6434por van den Berg, Elske, Bal, Suzanne M, Kuipers, Maria T, Matute-Bello, Gustavo, Lutter, René, Bos, Albert P, van Woensel, Job B M, Bem, Reinout A“…Experimental studies on ARDS have shown that inhibition of apoptosis in the lungs reduces lung epithelial injury. …”
Publicado 2015
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6435por Ehrnthaller, Christian, Flierl, Michael, Perl, Mario, Denk, Stephanie, Unnewehr, Heike, Ward, Peter A., Radermacher, Peter, Ignatius, Anita, Gebhard, Florian, Chinnaiyan, Arul, Huber-Lang, Markus“…Especially in multiple injured patients after blunt chest trauma ALI/ARDS [acute respiratory distress syndrome (ARDS)] is frequent. …”
Publicado 2015
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6436por Stephens, R Scott, Johnston, Laura, Servinsky, Laura, Kim, Bo S, Damarla, Mahendra“…These results support the testing of imatinib as a novel pharmacologic agent in the treatment of Gram-negative sepsis and sepsis-induced ARDS.…”
Publicado 2015
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6437por Venkategowda, Pradeep M., Rao, S. Manimala, Harde, Yogesh R., Raut, Mithilesh K., Mutkule, Dnyaneshwar P., Munta, Kartik, Rao, Mallela V.“…CONCLUSION: Early prone combined with ACPC-IRV in H1N1 patients having severe ARDS can be used as a rescue therapy and it should be confirmed by large observational studies.…”
Publicado 2016
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6438“…RESULTS: The patients with BPD had significantly increased numbers of fibrocytes compared to the controls (p < 0.01). Patients with ARDS were not different from healthy control subjects. …”
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6439por Meng, Jian-biao, Lai, Zhi-zhen, Xu, Xiu-juan, Ji, Chun-lian, Hu, Ma-hong, Zhang, Geng“…To investigate the effects of 72-hour early-initiated continuous venovenous hemofiltration (ECVVH) treatment in patients with septic-shock-induced acute respiratory distress syndrome (ARDS) (not acute kidney injury, AKI) with regard to serum E-selectin and measurements of lung function and hemodynamic stability. …”
Publicado 2016
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6440por Wynne, Brandi M., Zou, Li, Linck, Valerie, Hoover, Robert S., Ma, He-Ping, Eaton, Douglas C.“…Acute lung injury leading to acute respiratory distress (ARDS) is a global health concern. ARDS patients have significant pulmonary inflammation leading to flooding of the pulmonary alveoli. …”
Publicado 2017
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