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  1. 6461
    “…It is considered that it could be effective in ALI/ARDS treatment by ensuring possible COX-2 inhibition. …”
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    Efficacy of thymoquinone in the treatment of experimental lipopolysaccharide-induced acute lung injury
  2. 6462
    “…The studies not related to coronavirus are all in ARDS conditions; four of them are in Phase 1 and three in Phase 2. …”
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    Review of Trials Currently Testing Stem Cells for Treatment of Respiratory Diseases: Facts Known to Date and Possible Applications to COVID-19
  3. 6463
    “…The use of conscious PP in ARDS warrants further investigation in randomised controlled trials.…”
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    Early conscious prone positioning in patients with COVID-19 receiving continuous positive airway pressure: a retrospective analysis
  4. 6464
    “…However, in some instances, it might result in acute respiratory distress syndrome (ARDS) that poses a significant mortality risk. ARDS is postulated to be mediated by a surge of pro-inflammatory cytokines and chemokines, leading to a dysregulated hyper inflammatory response. …”
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    The efficacy of colchicine in the management of coronavirus disease 2019: A protocol for systematic review and meta-analysis
  5. 6465
    “…Drugs like pentoxifylline have already shown improvement of the symptoms of ARDS and caffeine has been in clinical use for decades to treat apnea of prematurity (AOP) in preterm infants and improve respiratory function. …”
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    Can pentoxifylline and similar xanthine derivatives find a niche in COVID-19 therapeutic strategies? A ray of hope in the midst of the pandemic
  6. 6466
    “…Most of them required mechanical ventilation and someone in prone position (PP) too, because of acute respiratory distress syndrome (ARDS). During PP, trans-esophageal echocardiography (TEE) is not always easy, mainly due to the forced position of the neck of the patient. …”
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    Trans-thoracic Echocardiography in Prone Positioning COVID-19 Patients: a Small Case Series
  7. 6467
    “…Echocardiographic parameters, specifically focused on RV (dimensions and function) and pulmonary circulation (systolic pulmonary arterial pressures, RV wall thickness), are to be measured in a COVID-19 patient with respiratory failure and ARDS. They have been selected on the basis of their feasibility (that is easy to be measured, even in short time) and usefulness for clinical monitoring. …”
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    Echocardiographic assessment of the right ventricle in COVID -related acute respiratory syndrome
  8. 6468
    “…There is evidence from preclinical studies that supports its preventive actions against ALI/ARDS. Moreover, ASX has a potent PPARs activity. …”
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    Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19
  9. 6469
    “…Prone positioning is a therapeutic choice in severe ARDS patients with obesity. Prophylactic NIV should be considered after extubation to prevent re-intubation. …”
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    How to ventilate obese patients in the ICU
  10. 6470
    por Chong, Woon H., Saha, Biplab K.
    Publicado 2021
    “…Although acute hypoxic respiratory failure (AHRF) and acute respiratory distress syndrome (ARDS) are the main features of the disease, the involvement of other organs needs to be explored. …”
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    Relationship Between Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the Etiology of Acute Kidney Injury (AKI)
  11. 6471
    “…As a severe complication of influenza infection, acute respiratory distress syndrome (ARDS) has higher morbidity and mortality. Although IL-36γ has been proven to promote inflammation at epithelial sites and protect against specific pathogen infection, the detailed roles in severe influenza infection remain poorly understood. …”
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    High Expression of IL-36γ in Influenza Patients Regulates Interferon Signaling Pathway and Causes Programmed Cell Death During Influenza Virus Infection
  12. 6472
    “…ACE-I or ARB was also associated with severe complications, such as acute respiratory distress syndrome (ARDS) (adjusted odds ratio [aOR], 2.58; 95% CI, 1.02–6.51; P = 0.045) and acute kidney injury (AKI) (aOR, 3.06; 95% CI, 1.15–8.15; P = 0.026). …”
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    Adverse impact of renin–angiotensin system blockade on the clinical course in hospitalized patients with severe COVID-19: a retrospective cohort study
  13. 6473
    “…The risk of ARDS after neoadjuvant neoadjuvant chemoradiation therapy with pembrolizumab has to be studied in the further analysis.…”
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    The feasibility and safety of radical esophagectomy in patients receiving neoadjuvant chemoradiotherapy with pembrolizumab for esophageal squamous cell carcinoma
  14. 6474
    “…The purpose of this meta-analysis was to compare the efficacy and safety of prone versus supine position ventilation for adult acute respiratory distress syndrome (ARDS) patients. The electronic databases of PubMed, Embase, and the Cochrane Library were systematically searched from their inception up to September 2020. …”
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    Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials
  15. 6475
    “…Acute Respiratory Discomfort Syndrome (ARDS) is the most common immunopathological event in SARS-CoV-2, SARS-CoV, and MERS-CoV infections. …”
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    Cathepsin L in COVID-19: From Pharmacological Evidences to Genetics
  16. 6476
    “…Acute respiratory distress syndrome/acute lung injury (ARDS/ALI) is histologically characterized by extensive alveolar barrier disruption and excessive fibroproliferation responses. …”
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    Protectin DX promotes epithelial injury repair and inhibits fibroproliferation partly via ALX/PI3K signalling pathway
  17. 6477
    “…The primary effect of spironolactone in reducing pulmonary edema may also be beneficial in COVID-19 ARDS. Spironolactone is a well-known, widely used and safe anti-hypertensive and antiandrogenic medication. …”
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    COVID-19—The Potential Beneficial Therapeutic Effects of Spironolactone during SARS-CoV-2 Infection
  18. 6478
    “…Cohorts exhibiting severe lung failure in the form of acute respiratory distress syndrome (ARDS) have been well characterized. Patients without ARDS but in need of supplementary oxygen have received much less attention. …”
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    Clinical course of COVID-19 patients needing supplemental oxygen outside the intensive care unit
  19. 6479
    “…RESULTS: The most severe alterations are found in the lungs by diffuse alveolar damage as a symptom of an acute respiratory distress syndrome (ARDS), in part with fibrosis. Thrombosis of small- to mid-sized pulmonary arteries is associated with hemorrhagic lung infarction. …”
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    Systemische Auswirkungen und klinische Aspekte der SARS-CoV-2-Infektion
  20. 6480
    “…Second, curcumin protects from lethal pneumonia and ARDS via targeting NF-κB, inflammasome, IL-6 trans signal, and HMGB1 pathways. …”
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    Antiviral and immunomodulatory activity of curcumin: A case for prophylactic therapy for COVID-19
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