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6901por Hartmann, Erik K, Thomas, Rainer, Liu, Tanghua, Stefaniak, Joanna, Ziebart, Alexander, Duenges, Bastian, Eckle, Daniel, Markstaller, Klaus, David, Matthias“…METHODS: Following animal care committee approval ARDS was induced by bronchoalveolar lavage followed by injurious ventilation in 21 anaesthetized pigs. …”
Publicado 2014
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6902por Lalu, Manoj M, Moher, David, Marshall, John, Fergusson, Dean, Mei, Shirley HJ, Macleod, Malcolm, Griffin, Gilly, Turgeon, Alexis F, Rudnicki, Michael, Fishman, Jason, Avey, Marc T, Skidmore, Becky, Grimshaw, Jeremy M, Stewart, Duncan J, Singh, Kavita, McIntyre, Lauralyn“…BACKGROUND: Acute respiratory distress syndrome (ARDS) in humans is caused by an unchecked proinflammatory response that results in diffuse and severe lung injury, and it is associated with a mortality rate of 35 to 45%. …”
Publicado 2014
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6903por Tanaka, Lilian Maria Sobreira, Azevedo, Luciano Cesar Pontes, Park, Marcelo, Schettino, Guilherme, Nassar, Antonio Paulo, Réa-Neto, Alvaro, Tannous, Luana, de Souza-Dantas, Vicente Ces, Torelly, André, Lisboa, Thiago, Piras, Claudio, Carvalho, Frederico Bruzzi, de Oliveira Maia, Marcelo, Giannini, Fabio Poianas, Machado, Flavia Ribeiro, Dal-Pizzol, Felipe, de Carvalho, Alexandre Guilherme Ribeiro, dos Santos, Ronaldo Batista, Tierno, Paulo Fernando Guimarães Morando Marzocchi, Soares, Marcio, Salluh, Jorge Ibrain Figueira“…Longer duration of ventilatory support was observed (7 (4 to 10) versus 5 (3 to 9) days, P = 0.041) and more tracheostomies were performed in the deep sedation group (38.9% versus 22%, P = 0.001) despite similar PaO(2)/FiO(2) ratios and acute respiratory distress syndrome (ARDS) severity. In a multivariate analysis, age (Odds Ratio (OR) 1.02; 95% confidence interval (CI) 1.00 to 1.03), Charlson Comorbidity Index >2 (OR 2.06; 95% CI, 1.44 to 2.94), Simplified Acute Physiology Score 3 (SAPS 3) score (OR 1.02; CI 95%, 1.00 to 1.04), severe ARDS (OR 1.44; CI 95%, 1.09 to 1.91) and deep sedation (OR 2.36; CI 95%, 1.31 to 4.25) were independently associated with increased hospital mortality. …”
Publicado 2014
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6904“…CONCLUSIONS: ECMO was safe and effective for patients with ongoing cardiac arrest or ARDS after a near-drowning incident and can be used as a resuscitative strategy in near-drowning patients with cardiac or pulmonary failure resistant to conventional ventilator therapy.…”
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6905por Li, Li-Fu, Lee, Chung-Shu, Lin, Chang-Wei, Chen, Ning-Hung, Chuang, Li-Pang, Hung, Chen-Yiu, Liu, Yung-Yang“…BACKGROUND: Mechanical ventilation (MV) used in patients with acute respiratory distress syndrome (ARDS) can cause diffuse lung inflammation, an effect termed ventilator-induced lung injury, which may produce profound pulmonary fibrogenesis. …”
Publicado 2017
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6906“…BACKGROUND: The lung-protective ventilation bundle has been shown to reduce mortality in adult acute respiratory distress syndrome (ARDS). This concept has expanded to other areas of acute adult ventilation and is recommended for pediatric ventilation. …”
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6907por Gattinoni, Luciano, Marini, John J., Collino, Francesca, Maiolo, Giorgia, Rapetti, Francesca, Tonetti, Tommaso, Vasques, Francesco, Quintel, Michael“…The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS) arise from two main causes: unphysiological increases of transpulmonary pressure and unphysiological increases/decreases of pleural pressure during positive or negative pressure ventilation. …”
Publicado 2017
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6908por Li, Li‐Fu, Kao, Kuo‐Chin, Liu, Yung‐Yang, Lin, Chang‐Wei, Chen, Ning‐Hung, Lee, Chung‐Shu, Wang, Chih‐Wei, Yang, Cheng‐Ta“…Mechanical ventilation (MV) used in patients with acute respiratory distress syndrome (ARDS) can increase lung inflammation and pulmonary fibrogenesis. …”
Publicado 2017
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6909por Zheng, Shengxing, Wang, Qian, D'Souza, Vijay, Bartis, Dom, Dancer, Rachel, Parekh, Dhruv, Gao, Fang, Lian, Qingquan, Jin, Shengwei, Thickett, David R“…Together, these results suggest a potential new therapeutic strategy for preventing and treating chronic diseases (such as idiopathic pulmonary fibrosis) as well as the fibroproliferative phase of ARDS by targeting RvD1 actions that emphasizes natural resolution signaling pathways.…”
Publicado 2018
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6910“…A higher white blood cell count (P = 0.05) and the complications of ARDS (P = 0.004) and encephalopathy (P = 0.004) were associated with mortality. …”
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6911por Deng, Guoying, Dai, Chenyun, Chen, Jinyuan, Ji, Anqi, Zhao, Jingpeng, Zhai, Yue, Kang, Yingjie, Liu, Xijian, Wang, Yin, Wang, Qiugen“…RESULTS: In the present study, we found that in the rat model of ARDS, Se@SiO(2) nanocomposites induced SOD and GSH indirectly to reduce ROS damage. …”
Publicado 2018
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6912por Banjas, Norbert, Hopf, Hans-Bernd, Hanisch, Ernst, Friedrichson, Benjamin, Fichte, Julia, Buia, Alexander“…Obviously, the experience with ECMO has to be taken into account when defining the role of ECMO in ARDS, cardiogenic, and septic shock.…”
Publicado 2018
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6913por Yokomichi, Hiroshi, Mochizuki, Mie, Lee, Joseph Jonathan, Kojima, Reiji, Yokoyama, Tetsuji, Yamagata, Zentaro“…Of these, 3361 were acute respiratory failure, 27 253 pneumonia, 18 ARDS, 2603 febrile seizure and 159 encephalitis/encephalopathy. …”
Publicado 2019
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6914por Liu, Songqiao, Zhao, Zhanqi, Tan, Li, Wang, Lihui, Möller, Knut, Frerichs, Inéz, Yu, Tao, Huang, Yingzi, Pan, Chun, Yang, Yi, Qiu, Haibo“…METHODS: ARDS was introduced with repeated bronchoalveolar lavage followed by injurious mechanical ventilation in ten healthy male pigs (51.2 ± 1.9 kg). …”
Publicado 2020
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6915“…The SARS-CoV-2 could in some case induce excessive and aberrant non-effective host immune responses that are associated with potentially fatal severe lung injury and patients can develop acute respiratory distress syndrome (ARDS). Cytokine release syndrome and viral ARDS result from uncontrolled severe acute inflammation. …”
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6916por Zou, Lei, Sun, Jiakui, Liu, Ying, Zhang, Wenhao, Jiang, Wei, Yuan, Shoutao, Shi, Qiankun“…And then we found that it was complicated with acute cor pulmonale(ACP) by ultrasound examination, dobutamine and diuretic were used for the treatment of ACP caused by ARDS successfully, and the P/F ratio went up to about 250mmHg. …”
Publicado 2020
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6917por Shah, Sachin J., Barish, Peter N., Prasad, Priya A., Kistler, Amy, Neff, Norma, Kamm, Jack, Li, Lucy M., Chiu, Charles Y., Babik, Jennifer M., Fang, Margaret C., Abe-Jones, Yumiko, Alipanah, Narges, Alvarez, Francisco N., Botvinnik, Olga Borisovna, Castaneda, Gloria, Dadasovich, Rand M., Davis, Jennifer, Deng, Xianding, DeRisi, Joseph L., Detweiler, Angela M., Federman, Scot, Haliburton, John, Hao, Samantha, Kerkhoff, Andrew D., Kumar, G. Renuka, Malcolm, Katherine B., Mann, Sabrina A., Martinez, Sandra, Mary, Rupa K., Mick, Eran, Mwakibete, Lusajo, Najafi, Nader, Peluso, Michael J., Phelps, Maira, Pisco, Angela Oliveira, Ratnasiri, Kalani, Rubio, Luis A., Sellas, Anna, Sherwood, Kyla D., Sheu, Jonathan, Spottiswoode, Natasha, Tan, Michelle, Yu, Guixia, Kangelaris, Kirsten Neudoerffer, Langelier, Charles“…Patients with COVID-19 were more likely to be admitted to the hospital, have longer hospitalizations and develop ARDS, and were unlikely to have co-existent viral infections. …”
Publicado 2020
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6918por Hamadah, Hala, Alahmad, Barrak, Behbehani, Mohammad, Al-Youha, Sarah, Almazeedi, Sulaiman, Al-Haddad, Mohannad, Jamal, Mohammad H., Al-Sabah, Salman“…Non-Kuwaitis had also higher odds of ARDS (OR:2.44, 95% CI 1.23–5.09) and pneumonia (OR: 2.24, 95% CI 1.27–4.12). …”
Publicado 2020
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6919por Shin, Kyung Min, Choi, Jiwoong, Chae, Kum Ju, Jin, Gong Yong, Eskandari, Ali, Hoffman, Eric A., Hall, Chase, Castro, Mario, Lee, Chang Hyun“…BACKGROUND: Previous studies suggested that the prone position (PP) improves oxygenation and reduces mortality among patients with acute respiratory distress syndrome (ARDS). However, the mechanism of this clinical benefit of PP is not completely understood. …”
Publicado 2020
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6920por Zotzmann, Viviane, Lang, Corinna N., Wengenmayer, Tobias, Bemtgen, Xavier, Schmid, Bonaventura, Mueller-Peltzer, Katharina, Supady, Alexander, Bode, Christoph, Duerschmied, Daniel, Staudacher, Dawid L.“…We retrospectively evaluated all SARS-CoV2-associated ARDS patients admitted to our ICU between March 8th and May 31th 2020. …”
Publicado 2020
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