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  1. 6921
    “…Demographics, data on physiology, resuscitation, MODS/ARDS, and infectious complications were prospectively collected. …”
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    Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
  2. 6922
    “…Most patients had organ dysfunction, including 13 (92.9%) with acute respiratory distress syndrome (ARDS), 4 (28.6%) with cardiac injury, 3 (21.4%) with acute kidney injury, and 3 (21.4%) with liver dysfunction. …”
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    Clinical characteristics of 14 COVID-19 deaths in Tianmen, China: a single-center retrospective study
  3. 6923
    por Yaqinuddin, Ahmed, Kashir, Junaid
    Publicado 2020
    “…The pathogenesis of SARS-CoV-2 and its pathology of associated acute lung injury (ALI), acute respiratory distress syndrome (ARDS), sepsis, coagulopathy and multiorgan failure is not known. …”
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    Novel therapeutic targets for SARS-CoV-2-induced acute lung injury: Targeting a potential IL-1β/neutrophil extracellular traps feedback loop
  4. 6924
    por Wang, Stephani C., Wang, Yu-Feng
    Publicado 2021
    “…Along with acute respiratory distress syndrome (ARDS), new and old cardiovascular injuries are important causes of significant morbidity and mortality in COVID-19. …”
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    Cardiovascular protective properties of oxytocin against COVID-19
  5. 6925
    “…However, like any population at risk, more serious symptoms can appear such as pneumonia or ARDS. In our study, we propose to define the clinical, biological and therapeutic characteristics as well as the management of a series of pregnant women suffering from COVID-19. …”
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    Infection par le SARS-CoV-2 chez les femmes enceintes: série tunisienne de 11 cas
  6. 6926
    por Pandanaboyana, Sanjay, Moir, John, Leeds, John S, Oppong, Kofi, Kanwar, Aditya, Marzouk, Ahmed, Belgaumkar, Ajay, Gupta, Ajay, Siriwardena, Ajith K, Haque, Ali Raza, Awan, Altaf, Balakrishnan, Anita, Rawashdeh, Arab, Ivanov, Bogdan, Parmar, Chetan, M Halloran, Christopher, Caruana, Clifford, Borg, Cynthia-Michelle, Gomez, Dhanny, Damaskos, Dimitrios, Karavias, Dimitrios, Finch, Guy, Ebied, Husam, K Pine, James, R A Skipworth, James, Milburn, James, Latif, Javed, Ratnam Apollos, Jeyakumar, El Kafsi, Jihène, Windsor, John A, Roberts, Keith, Wang, Kelvin, Ravi, Krish, V Coats, Maria, Hollyman, Marianne, Phillips, Mary, Okocha, Michael, SJ Wilson, Michael, A Ameer, Nadeem, Kumar, Nagappan, Shah, Nehal, Lapolla, Pierfrancesco, Magee, Connor, Al-Sarireh, Bilal, Lunevicius, Raimundas, Benhmida, Rami, Singhal, Rishi, Balachandra, Srinivasan, Demirli Atıcı, Semra, Jaunoo, Shameen, Dwerryhouse, Simon, Boyce, Tamsin, Charalampakis, Vasileios, Kanakala, Venkat, Abbas, Zaigham, Nayar, Manu
    Publicado 2021
    “…Secondary outcome measures were aetiology of AP, intensive care unit (ICU) admission, length of hospital stay, local complications, acute respiratory distress syndrome (ARDS), persistent organ failure and 30-day mortality. …”
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    SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30-day mortality: COVID PAN collaborative study
  7. 6927
    “…Numerous clinical studies have started worldwide and demonstrated that MSCs have great potential for ARDS treatment in COVID-19 patients. Preliminary data have shown that MSCs and MSC-derived secretome appear to be promising in the treatment of COVID-19. …”
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    Potency of Mesenchymal Stem Cell and Its Secretome in Treating COVID-19
  8. 6928
    “…Among other complications, COVID-19leads to fatal pneumonia, acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) due to development of cytokine storm (CS). …”
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    Sequential doxycycline and colchicine combination therapy in Covid-19: The salutary effects
  9. 6929
    “…Four patients required VV ECMO for severe hypoxemia secondary to COVID19 ARDS. One patient required VA ECMO due to viral myocarditis secondary to COVID19. …”
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    Extracorporeal Membrane Oxygenation Dependent COVID19 Hospital Transfers
  10. 6930
    “…Hyperactivation of the immune system through obesity and diabetes may enhance infection severity complicated by Acute Respiratory Distress Syndrome (ARDS). The objective was to determine the circulatory biomarkers for macrophage activation at baseline and after serum glucose normalization in obese type 2 diabetes (OT2D) subjects. …”
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    Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19
  11. 6931
    “…The aim of this study was to evaluate the safety and describe the clinical changes after IV administration of allogeneic human umbilical cord MSC (ahUCMSC), in patients with bilateral pneumonia caused by COVID-19, complicated with severe ARDS, as compassionate treatment. This was a pilot, open-label, prospective, longitudinal study. …”
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    Mesenchymal Stem Cells for the Compassionate Treatment of Severe Acute Respiratory Distress Syndrome Due to COVID 19
  12. 6932
    “…Compared with non-severe group, proportion of hypertension (OR: 1.98, 95% CI: 1.62–2.42), diabetes (OR: 2.04, 95% CI: 1.67–2.50), cardiovascular disease (OR: 2.78, 95% CI: 2.00–3.86), and cancer (OR: 1.75, 95% CI: 1.40–2.18) were statistically significant higher in severe group. 24.7% patients presented with ARDS. The pooled effect of ARDS in severe and non-severe cases was 42.69 (OR: 42.69, 95% CI: 21.62–84.31). …”
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    Comparison of clinical manifestations, pre-existing comorbidities, complications and treatment modalities in severe and non-severe COVID-19 patients: A systemic review and meta-analysis
  13. 6933
    por Hoang, Tung, Tran Thi Anh, Tho
    Publicado 2021
    “…Preexisting hypertension and diabetes additionally increased the risk of acute respiratory distress syndrome (ARDS). Among comorbidities, COPD had the highest probability of leading to severe COVID-19, ICU admission, and liver injury, while malignancy was most likely to cause ARDS and cardiac injury. …”
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    Comparison of Comorbidities in Relation to Critical Conditions among Coronavirus Disease 2019 Patients: A Network Meta-Analysis
  14. 6934
    “…BACKGROUND: Subphenotypes have been identified in patients with sepsis and ARDS and are associated with different outcomes and responses to therapies. …”
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    Identification of Distinct Clinical Subphenotypes in Critically Ill Patients With COVID-19
  15. 6935
    “…Background: One of the important pathogenesis of acute respiratory distress syndrome (ARDS) is the dysfunction of pulmonary microvascular endothelial barrier induced by a hyperinflammatory immune response. …”
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    Inflammatory Immune Cytokine TNF-α Modulates Ezrin Protein Activation via FAK/RhoA Signaling Pathway in PMVECs Hyperpermeability
  16. 6936
    “…SUBJECTS/METHODS: Patients admitted to the ICU for COVID-19 acute respiratory distress syndrome (ARDS) were included retrospectively. The following data were collected: comorbidities, body mass index (BMI), the severity of ARDS assessed with PaO(2)/FiO(2) (P/F) ratios, disease severity measured by the Simplified Acute Physiology Score II (SAPS II), management and outcomes. …”
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    Obesity and mortality in critically ill COVID-19 patients with respiratory failure
  17. 6937
    “…PURPOSE: In this retrospective study, we compared inhaled sedation with isoflurane to intravenous propofol in invasively ventilated COVID-19 patients with ARDS (Acute Respiratory Distress Syndrome). METHODS: Charts of all 20 patients with COVID-19 ARDS admitted to the ICU of a German University Hospital during the first wave of the pandemic between 22/03/2020 and 21/04/2020 were reviewed. …”
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    Comparison of isoflurane and propofol sedation in critically ill COVID-19 patients—a retrospective chart review
  18. 6938
    “…INTRODUCTION: Angiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin-angiotensin system (RAS) that has been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). Enhancing ACE2 activity using GSK2586881, a recombinant form of human ACE2, could be beneficial in diseases such as ARDS but may blunt the hypoxic pulmonary vasoconstriction (HPV) response and potentially impact systemic and tissue oxygenation. …”
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    Effects of Recombinant Human Angiotensin-Converting Enzyme 2 on Response to Acute Hypoxia and Exercise: A Randomised, Placebo-Controlled Study
  19. 6939
    “…Results: We included 30 patients with moderate-to-severe ARDS. In patients with a high R/I ratio, the TE-LUS RAS was significantly higher in the lower lobes than in the upper lobes (1.20 [1.12–1.63] vs. 1.05 [0.89–1.38]; p = 0.05). …”
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    Transoesophageal Ultrasound Assessment of Lung Aeration in Patients With Acute Respiratory Distress Syndrome
  20. 6940
    “…OBJECTIVE: Coronavirus disease 2019 (COVID‐19) has progressed rapidly around the world, reaching a lethality of up to 20% due to acute respiratory distress syndrome (ARDS). This latter condition is a relevant concern for systemic lupus erythematosus (SLE); however, data on this topic are limited to few case series. …”
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    Poor Prognosis of COVID‐19 Acute Respiratory Distress Syndrome in Lupus Erythematosus: Nationwide Cross‐Sectional Population Study Of 252 119 Patients
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