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7341“…Acute respiratory distress syndrome (ARDS) in COVID-19 is characterized by a severe cytokine storm. …”
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7342por Stancioiu, Felician, Papadakis, Georgios Z., Kteniadakis, Stelios, Izotov, Boris Nikovaevich, Coleman, Michael D., Spandidos, Demetrios A., Tsatsakis, Aristidis“…The material is organized in three sections: i) Clinical aspects of COVID-19; acute respiratory distress syndrome (ARDS); known treatments; ii) Structure and functions of SARS-CoV2 and proposed antiviral drugs; iii) The combination of arginine-ascorbate.…”
Publicado 2020
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7343“…Studies suggest that mortality due to COVID 19 is mainly attributed to the hyper inflammatory response leading to cytokine storm and ARDS in infected patients. Sphingosine-1-phosphate receptor 1 (S1PR1) analogs, AAL-R and RP-002, have earlier provided in-vivo protection from the pathophysiological response during H1N1 influenza infection and improved mortality. …”
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7344por Holmen, Ian C, Kent, Andrew, Lakritz, Stephanie, Brickson, Claire, Mastalerz, Katarzyna“…Coronavirus disease 2019 (COVID-19) can cause acute respiratory distress syndrome (ARDS) that is associated with high mortality among patients requiring invasive mechanical ventilation. …”
Publicado 2020
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7345por Wang, Yongyong, Zeng, Chenxi, Dong, Liming, Liu, Changyu, Cai, Yixing, Zhang, Ni, Fu, Xiangning“…All 29 patients were treated conservatively, including with closed thoracic drainage, instead of with thoracotomy. Six patients died of ARDS or craniocerebral injury, but the others stabilized. …”
Publicado 2020
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7346“…Acute respiratory distress syndrome (ARDS) leads to refractory hypoxemia and demise. Severe morbid obesity as well as race may be unidentified risk factors for the development of severe Illness in patients with COVID-19.…”
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7347“…COVID-19 affects the upper respiratory tract, lungs (pneumonia, acute respiratory distress syndrome [ARDS]), heart, liver, gastrointestinal tract, and other organs. …”
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7348“…RECOMMENDATIONS: Lung ultrasound in patients with COVID-19 offers similar performance as CT and is superior when compared to X‑ray in evaluating pneumonia and acute respiratory distress syndrome (ARDS). Lung ultrasound plays an important role in the emergency room and intensive care unit. …”
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7349“…SARS-CoV-2 mainly invades the cells by binding to the angiotensin converting enzyme 2 (ACE2) receptor, leading to the injury of respiratory system, cardiovascular system, digestive system, and urinary system, and even secondary to acute respiratory distress syndrome (ARDS) and systemic inflammatory response, resulting in multiple organ failure. …”
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7350“…Silent hypoxia, atypical acute respiratory distress syndrome (ARDS), stroke, olfactory loss, myocarditis, and increased mortality rates in the elderly, in men, in African-Americans, and in patients with obesity, diabetes, and cancer—all bear the fingerprints of the renin-angiotensin system (RAS) imbalance, suggesting that RAS is the common culprit. …”
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7351por Daniela, Martínez, Felipe, Salech, Van Nicolette, Sint Jan, Tomás, Regueira, Eli, Villalabeitia, Jorge, Rufs, Christian, Fajardo, Roberto, Castillo, Jose, Iñiguez, Luisa, Durán, Rodrigo, Díaz“…These patients can experience rapid progression to profound hypoxemia and severe acute respiratory distress syndrome (ARDS). Some patients, despite receiving lung-protective ventilation and maximal medical therapy, develop refractory hypoxemia, rendering candidates for extracorporeal membrane oxygenation (ECMO) support. …”
Publicado 2020
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7352“…Despite tremendous advancements, there are no effective pharmacological therapies capable of curing diseases such as COPD (chronic obstructive pulmonary disease), ARDS (acute respiratory distress syndrome), and COVID-19. …”
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7353por Abruzzo, Provvidenza M., Canaider, Silvia, Pizzuti, Valeria, Pampanella, Luca, Casadei, Raffaella, Facchin, Federica, Ventura, Carlo“…Cellular senescence plays a very important role in organismal aging increasing with age and in age-related diseases (ARDs). This process involves physiological, structural, biochemical, and molecular changes of cells, leading to a characteristic trait referred to “senescence-associated secretory phenotype (SASP).” …”
Publicado 2020
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7354“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently discovered coronavirus which has caused a global outbreak of severe pneumonia with complications leading to hypoxic respiratory failure, acute respiratory distress syndrome (ARDS), cytokine storm, disseminated intravascular coagulation (DIC), and even gastrointestinal symptoms. …”
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7355por Kost-Alimova, Maria, Sidhom, Eriene-Heidi, Satyam, Abhigyan, Chamberlain, Brian T., Dvela-Levitt, Moran, Melanson, Michelle, Alper, Seth L., Santos, Jean, Gutierrez, Juan, Subramanian, Ayshwarya, Byrne, Patrick J., Grinkevich, Elizabeth, Reyes-Bricio, Estefanía, Kim, Choah, Clark, Abbe R., Watts, Andrew J.B., Thompson, Rebecca, Marshall, Jamie, Pablo, Juan Lorenzo, Coraor, Juliana, Roignot, Julie, Vernon, Katherine A., Keller, Keith, Campbell, Alissa, Emani, Maheswarareddy, Racette, Matthew, Bazua-Valenti, Silvana, Padovano, Valeria, Weins, Astrid, McAdoo, Stephen P., Tam, Frederick W.K., Ronco, Luciene, Wagner, Florence, Tsokos, George C., Shaw, Jillian L., Greka, Anna“…Elevated MUC1 levels predict the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) and correlate with poor clinical outcomes. …”
Publicado 2020
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7356por Domingo Ribas, Christian“…The therapeutic approach is divided into two big sections: the pharmacological treatment for the phase of viral replication, cytokine storm or late respiratory events (which includes the adult respiratory distress syndrome (ARDS)) and the treatment of the respiratory failure In every stage, we discuss the pathophysiology and comment (accept or rule out) the pharmacological options according to the present evidence. …”
Publicado 2020
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7357por Poggiali, Erika, Vercelli, Andrea, Vadacca, Giovanni Battista, Schiavo, Roberta, Mazzoni, Silvana, Ioannilli, Eva, Demichele, Elena, Magnacavallo, Andrea“…Severe acute respiratory distress syndrome (ARDS) is the main cause of death: its management and treatment should be tailored to the individual COVID-19 patient’s phenotype. …”
Publicado 2020
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7358“…Coronavirus disease 2019 (COVID-19) is a virus-induced respiratory disease that may progress to acute respiratory distress syndrome (ARDS) and is triggered by immunopathological mechanisms that cause excessive inflammation and leukocyte dysfunction. …”
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7359“…COVID-19 is highly infectious and is characterized by an acute respiratory illness that varies from mild flu-like symptoms to the life-threatening acute respiratory distress syndrome (ARDS). As such, there is an urgent need for the development of new therapeutic strategies, which combat the high mortality in severely ill COVID-19 patients. …”
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7360por Bruce, Samuel S., Kahan, Joshua, Huq, Tashfin, Santillan, Alejandro, Navi, Babak B., Merkler, Alexander E., Parikh, Neal S., Mir, Saad, Schweitzer, Andrew D., Segal, Alan Z.“…This series demonstrates a pattern of cerebrovascular events clinically masked by deep sedation required for management of COVID-19 related acute respiratory distress syndrome (ARDS). Of the 12 patients included, 10 had ischemic stroke, 4 of which had hemorrhagic conversion, and 2 had primary intracerebral hemorrhage. …”
Publicado 2021
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