“…Acute lung injury (ALI) is a common critical disease of the respiratory system that progresses into acute respiratory distress syndrome (ARDS), with high mortality, mainly related to pulmonary oxidative stress imbalance and severe inflammation. …”
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“…INTRODUCTION: Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a commonly occurring sequelae of traumatic injury resulting from indirect insults like hypovolemic shock and/or extrapulmonary sepsis. …”
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“…Inhalation injury was a significant indicator for ARDS which implies that proper screening for this type of injury is a key to predicting long-term treatment. …”
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“…Results: We included 84 ARDS COVID-19 surviving patients. Disease severity, complications, demographics, and comorbidities were similar between groups, but there were more women in wave 3 (w3). …”
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“…C-19-pna cases were also more likely to die and have an ARDS diagnosis compared to I-pna cases (25% vs 6.1%, p< .001; 10.8% vs 1.7%, p< .001 respectively); this was observed across age groups ≥ 50 years (p < .001). …”
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“…INTRODUCTION: To investigate haemodynamic and respiratory changes during lung recruitment and decremental positive end-expiratory pressure (PEEP) titration for open lung ventilation in patients with acute respiratory distress syndrome (ARDS) a prospective, clinical trial was performed involving 12 adult patients with ARDS treated in the surgical intensive care unit in a university hospital. …”
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“…ARDS is characterized by edema formation, and edema resolution occurs mainly due to the pneumocyte Na/K-ATPase activity. …”
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“…INTRODUCTION: Lung-protective ventilation reduced acute respiratory distress syndrome (ARDS) mortality. To minimize ventilator-induced lung injury (VILI), tidal volume is limited, high plateau pressures are avoided, and positive end-expiratory pressure (PEEP) is applied. …”
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“…METHODS: A one-hit injury ARDS model was established by repeated lung lavages in 18 piglets. …”
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“…RESULTS: LVt resulted in mild acute respiratory distress syndrome (ARDS) (P(a)O(2)/F(i)O(2) = 226.2 ± 17.1 mmHg) whereas APRV prevented ARDS (P(a)O(2)/F(i)O(2) = 465.7 ± 66.5 mmHg; p < 0.05). …”
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“…METHODS: This is a prospective, longitudinal, multi-site study of 196 acute respiratory distress syndrome (ARDS) survivors. More than 30 relevant sociodemographic, physical status, and mental health variables (representing participant characteristics prior to ARDS, at hospital discharge, and at the immediately preceding follow-up visit) were evaluated for association with missed assessments at 3, 6, 12, and 24-month follow-up visits (89–95% retention rates), using binomial logistic regression. …”
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“…BACKGROUND: High-frequency oscillatory ventilation (HFOV) use was associated with greater mortality in adult acute respiratory distress syndrome (ARDS). Nevertheless, HFOV is still frequently used as rescue therapy in paediatric acute respiratory distress syndrome (PARDS). …”
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“…All patients developed severe ARDS (PaO(2)/FiO(2)-Ratio 60 (55–92); lung injury score 3.8 (3.3–4.0)), were mechanically ventilated and on vasopressor support. …”
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“…In our case series of 18 critically ill patients with COVID-19 and ARDS, administration of ruxolitinib resulted in a clinical improvement that concurred to modify the standard course of disease. …”
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“…Secondary outcomes included acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), and need for mechanical ventilation. RESULTS: The median cohort patient age was 68 (56-76) years, 43% (n = 189) were female, and 41% (n = 179) were Caucasian. …”
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“…Complications associated with death included development of a new arrhythmia, bacteremia, pneumonia, ARDS, thrombosis, and new renal failure requiring HD (Table). …”
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“…CONCLUSION: Results showed that metabolic diseases comprising CVD, diabetes, hypertension, and respiratory diseases, including COPD, ARDS, are the most common comorbidities to severe condition and poor prognosis in covid-19 patients. …”
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“…BACKGROUND: Alveolar dead-space fraction (AVDSF), the volume of alveolar gas that does not participate in gas exchange, has been reported to predict mortality and morbidity in adults with acute respiratory distress syndrome (ARDS). This study aims to characterize AVDSF in patients with pediatric ARDS (PARDS), to determine its association with clinical outcomes and examine the validity of a previously studied cutoff (AVDSF > 0.25). …”
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“…BACKGROUND: Pulmonary microvascular endothelial cells (PMVECs) were not complex, and the endothelial barrier was destroyed in the pathogenesis progress of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). Previous studies have demonstrated that hepatocyte growth factor (HGF), which was secreted by bone marrow mesenchymal stem cells, could decrease endothelial apoptosis. …”
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“…BACKGROUND: Treatment of acute respiratory distress syndrome (ARDS) associated with COronaVIrus Disease-2019 (COVID-19) currently relies on dexamethasone and supportive mechanical ventilation, and remains associated with high mortality. …”
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