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7941por Yamaguchi, Eiichiro, Yao, Joshua, Aymond, Allison, Chrisey, Douglas B., Nieman, Gary F., Bates, Jason H. T., Gaver, Donald P.“…We investigate the susceptibility and time-dependent disruption of barrier function associated with pulmonary atelectrauma of epithelial cells that occurs in acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI). …”
Publicado 2022
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7942por Gitti, Nicola, Renzi, Stefania, Marchesi, Mattia, Bertoni, Michele, Lobo, Francisco A., Rasulo, Frank A., Goffi, Alberto, Pozzi, Matteo, Piva, Simone“…Although deep sedation (DS) may still be necessary for certain clinical scenarios, it should be limited to strict indications, such as mechanically ventilated patients with Acute Respiratory Distress Syndrome (ARDS), status epilepticus, intracranial hypertension, or those requiring target temperature management. …”
Publicado 2022
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7943por Dinnon, Kenneth H., Leist, Sarah R., Okuda, Kenichi, Dang, Hong, Fritch, Ethan J., Gully, Kendra L., De la Cruz, Gabriela, Evangelista, Mia D., Asakura, Takanori, Gilmore, Rodney C., Hawkins, Padraig, Nakano, Satoko, West, Ande, Schäfer, Alexandra, Gralinski, Lisa E., Everman, Jamie L., Sajuthi, Satria P., Zweigart, Mark R., Dong, Stephanie, McBride, Jennifer, Cooley, Michelle R., Hines, Jesse B., Love, Miriya K., Groshong, Steve D., VanSchoiack, Alison, Phelan, Stefan J., Liang, Yan, Hether, Tyler, Leon, Michael, Zumwalt, Ross E., Barton, Lisa M., Duval, Eric J., Mukhopadhyay, Sanjay, Stroberg, Edana, Borczuk, Alain, Thorne, Leigh B., Sakthivel, Muthu K., Lee, Yueh Z., Hagood, James S., Mock, Jason R., Seibold, Max A., O’Neal, Wanda K., Montgomery, Stephanie A., Boucher, Richard C., Baric, Ralph S.“…The mouse-adapted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain MA10 produces an acute respiratory distress syndrome (ARDS) in mice similar to humans. To investigate PASC pathogenesis, studies of MA10-infected mice were extended from acute to clinical recovery phases. …”
Publicado 2022
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7944por Jiang, Shuaiyu, Wu, Mengmeng, Lu, Xiaoguang, Zhong, Yilong, Kang, Xin, Song, Yi, Fan, Zhiwei“…Comparing LFR or adequate fluid resuscitation in hemorrhagic shock or septic shock patients, the summary odds ratio (OR) was 0.50 (95% confidence interval [CI] 0.42–0.60, P < .00001) for mortality, 0.46 (95% CI 0.31–0.70, P = .0002) for multiple organ dysfunction syndrome (MODS), 0.35 (95% CI 0.25–0.47) for acute respiratory distress syndrome (ARDS), and 0.33 (95% CI 0.20–0.56) for disseminated intravascular coagulation (DIC). …”
Publicado 2021
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7945“…Coronavirus disease 2019 (COVID-19) has been raging all around the world since the beginning of 2020, and leads to acute respiratory distress syndrome (ARDS) with strong cytokine storm which contributes to widespread tissue damage and even death in severe patients. …”
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7946“…Prolonged critical care stays commonly follow trauma, severe burn injury, sepsis, ARDS, and complications of major surgery. Although patients leave critical care following homeostatic recovery, significant additional diseases affect these patients during and beyond the convalescent phase. …”
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7947por Nadeem, Rashid, Rafeeq, Aju, Aga, Anas A, Siddiqua, Ayesha, Sharma, Ekta, Anwer, Doaa, Kafeel Khan, Mohd, Abdulla Mohammed Hussein, Mohamed, Omar Alshaikh SayedAhmed, Yusra, Ahmad Dar, Farooq“…Conclusion: SNIs are high in patients admitted to ICU for COVID-19 acute respiratory distress syndrome (ARDS). Although they do not impact mortality, they prolong the need for MV, LOSICU, and LOSH.…”
Publicado 2022
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7948por Khongthaw, Banlambhabok, Dulta, Kanika, Chauhan, Pankaj Kumar, Kumar, Vinod, Ighalo, Joshua O.“…In COVID-19, inflammation, and cytokine storm are the key pathogenic mechanisms, according to SARS-CoV-2 infection symptoms. ARDS develops in some vulnerable hosts, which is accompanied by an inflammatory "cytokine syndrome" that causes lung damage. …”
Publicado 2022
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7949por Setyo Nugroho, Gilang Muhammad, Marhana, Isnin Anang, Kusumastuti, Etty Hary, Semedi, Bambang Pujo, Maimunah, Ummi, Lefi, Achmad, Suyanto, Edi, Rosyid, Alfian Nur, Wahyu, Dwi, Wiratama, Priangga Adi, Anggoro, Adhitri, Rusgi Yandi, I Komang, Djuanda, Stephanie Natasha, Lilihata, Jilieanastasia Godrace, Supriadi, Pratama Rinjani, Lalu Galih, Nugraha, Ricardo Adrian“…Characteristics of patients with a mean age of patients were 48 years, male, the most common chief complaint was shortness of breath, mean symptom onset was 5 days, patient length of stay was 10 days, the most common cause of death was a combination of septic shock and ARDS and the most common comorbid diabetes mellitus. …”
Publicado 2022
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7950“…Up to 5% of affected persons may experience more severe COVID-19 illness, including severe coagulopathy, acute respiratory distress syndrome (ARDS) characterized by respiratory failure that requires supplementary oxygen and mechanical ventilation, and multi-organ failure. …”
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7951por Fiore, Donatella, Proto, Maria Chiara, Franceschelli, Silvia, Pascale, Maria, Bifulco, Maurizio, Gazzerro, Patrizia“…In COVID-19 patients, statins improve clinical outcomes, reducing Intensive Care Unit admission, the onset of ARDS, and in-hospital death. However, the safety of statins in COVID-19 patients has been debated, mainly for statins’ ability to induce the expression of the ACE2 receptor, the main entry route of SARS-CoV-2. …”
Publicado 2022
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7952“…An 18-year-old girl presenting with respiratory and gastrointestinal symptoms was found to have COVID-19 pneumonia and severe acute respiratory distress syndrome (ARDS). She was transferred to our pediatric intensive care unit (PICU) for ongoing mechanical ventilation and initiation of venovenous extracorporeal membrane oxygenation (VV-ECMO) for management of progressive hypoxic respiratory failure. …”
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7953“…The pathogenesis of COVID-19 is highly linked with over-active immune and inflammatory responses, leading to activated cytokine storm, which contribute to ARDS with worsen outcome. Currently, there is no effective therapeutic drug for the treatment of COVID-19. …”
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7954por Tsioulos, Georgios, Grigoropoulos, Ioannis, Moschopoulos, Charalampos D., Shapira, Shiran, Poulakou, Garyfallia, Antoniadou, Anastasia, Boumpas, Dimitrios, Arber, Nadir, Tsiodras, Sotirios“…Very recent data outline a possible therapeutic role not only in COVID-19 but also in other similar disease states, e.g., acute respiratory distress syndrome (ARDS) and sepsis where immune dysregulation plays a key pathophysiologic role. …”
Publicado 2022
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7955“…Advances in science and technology have permitted the development of more sophisticated therapies such as extracorporeal organ support (ECOS) therapies that includes renal replacement therapies (RRTs), venoarterial (VA) or veno-venous (VV) extracorporeal membrane Oxygenation (ECMO), extracorporeal CO2 removal (ECCO2R), liver support systems, hemoperfusion, and various blood purification devices, for the treatment of ARDS and septic shock.…”
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7956“…Recent literature describing the respiratory mechanics of patients with late-stage, unresolving, ARDS, however, has raised awareness of the potential diagnostic (and perhaps therapeutic) value of this unfamiliar and somewhat counterintuitive practice. …”
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7957por Ikrou, Hanane, Boustani, Salma, Ibenyahia, Abderrahmane, Marsafi, Oussama, Wakrim, Soukaina, Elmekkaoui, Adel, Benlenda, Othmane, Nassik, Hicham“…We report the case of a North African male patient hospitalized for acute respiratory distress syndrome (ARDS) secondary to covid19 pneumonia, complicated by the occurrence of multiple arterial thrombosis of the aorto-iliac axis with the rare finding of two free floating thrombus in the aorta and the right common iliac artery. …”
Publicado 2022
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7958por Bolat, Ecem, Eker, Furkan, Kaplan, Merve, Duman, Hatice, Arslan, Ayşenur, Saritaş, Sümeyye, Şahutoğlu, Arif Sercan, Karav, Sercan“…SARS-CoV-2 is known to cause complications that may include pneumonia, acute respiratory distress syndrome (ARDS), multi-organ failure, septic shock, and death. …”
Publicado 2022
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7959por Tiboldi, Akos, Hunyadi-Gulyas, Eva, Wohlrab, Peter, Schmid, Johannes A., Markstaller, Klaus, Klein, Klaus Ulrich, Tretter, Verena“…Patients presenting with insufficient tissue oxygenation and impaired lung function as in acute respiratory distress syndrome (ARDS) frequently require mechanical ventilation with supplemental oxygen. …”
Publicado 2022
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7960por Stroh, J.N., Smith, Bradford J., Sottile, Peter D., Hripcsak, George, Albers, David J.“…Mechanical ventilation is an essential tool in the management of Acute Respiratory Distress Syndrome (ARDS), but it exposes patients to the risk of ventilator-induced lung injury (VILI). …”
Publicado 2023
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