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8501por Zhang, Jiong, Cao, Fang, Wu, Shu-Kun, Xiang-Heng, Lu, Li, Wei, Li, Gui-sen, Wang, Jia“…Complications included ARDS (25.8%), AHF (22.6%), and septic shock (16.1%), etc. 64.5% of patients had remission, and 35.5% of patients had no remission with 6.5% deaths. …”
Publicado 2020
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8502por Middleton, Elizabeth A., He, Xue-Yan, Denorme, Frederik, Campbell, Robert A., Ng, David, Salvatore, Steven P., Mostyka, Maria, Baxter-Stoltzfus, Amelia, Borczuk, Alain C., Loda, Massimo, Cody, Mark J., Manne, Bhanu Kanth, Portier, Irina, Harris, Estelle S., Petrey, Aaron C., Beswick, Ellen J., Caulin, Aleah F., Iovino, Anthony, Abegglen, Lisa M., Weyrich, Andrew S., Rondina, Matthew T., Egeblad, Mikala, Schiffman, Joshua D., Yost, Christian Con“…COVID-19 affects millions of patients worldwide, with clinical presentation ranging from isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator support. Neutrophil extracellular traps (NETs) originate from decondensed chromatin released to immobilize pathogens, and they can trigger immunothrombosis. …”
Publicado 2020
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8503por Soeroto, Arto Yuwono, Soetedjo, Nanny Natalia, Purwiga, Aga, Santoso, Prayudi, Kulsum, Iceu Dimas, Suryadinata, Hendarsyah, Ferdian, Ferdy“…We included all original research articles in COVID-19 adult patients and obesity based on classification of Body Mass Index (BMI) and composite poor outcome which consist of ICU admission, ARDS, severe COVID-19, use of mechanical ventilation, hospital admission, and mortality. …”
Publicado 2020
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8504por Pirau, Letitia, Ottenhoff, Lauren, Williamson, Craig A., Ahmad, Shahid N., Wabl, Rafael, Nguyen, Andrew, Faiver, Laura, Rajajee, Venkatakrishna“…These two male patients, one aged 59-years and another aged 53-years, both with a history of hypertension and neurologically intact on admission, developed worsening COVID-19 associated acute respiratory distress syndrome (ARDS). Both required benzodiazepine, opioid, neuromuscular blockade, therapeutic anticoagulation, and vasopressor infusions in addition to renal replacement therapy. …”
Publicado 2020
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8505por Cao, Yukun, Han, Xiaoyu, Gu, Jin, Li, Yumin, Liu, Jia, Alwalid, Osamah, Cui, Yue, Zhang, Xin, Zheng, Chuansheng, Fan, Yanqing, Wu, Hanping, Shi, Heshui“…The multivariable regression analysis showed older age (OR: 1.142, 95% CI 1.059–1.231, p < 0.001), acute respiratory distress syndrome (ARDS) (OR: 10.142, 95% CI 1.611–63.853, p = 0.014), reduced lymphocyte count (OR: 0.004, 95% CI 0.001–0.306, p = 0.013), and elevated HRCT score (OR: 1.276, 95% CI 1.002–1.625, p = 0.049) to be independent predictors of mortality risk on admission in severe COVID-19 patients. …”
Publicado 2020
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8506“…Three patients developed an ARDS, including one who died. CONCLUSION: A limited number of patients with inflammatory rheumatic diseases suffered from COVID-19 infection. …”
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8507por Muralidharan, Priya, Jones, Brielle, Allaway, Graham, Biswal, Shyam S., Mansour, Heidi M.“…Chalcone derivatives are shown to possess excellent anti-inflammatory and anti-oxidant properties which are of great interest in treating respiratory diseases such as acute lung injury (ALI), acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis (PF). …”
Publicado 2020
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8508por Aung, Ar K, Aitken, Tess, Teh, Bing M, Yu, Christiaan, Ofori-Asenso, Richard, Chin, Ken L, Liew, Danny“…BACKGROUND: Angiotensin converting enzyme (ACE) genotypes are known to be associated with development of acute respiratory distress syndrome (ARDS) and resultant mortality. In the present study, we examined the association between distribution frequency of ACE genotypes and COVID-19 mortality. …”
Publicado 2020
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8509por Buonaguro, Franco M., Botti, Gerardo, Ascierto, Paolo Antonio, Pignata, Sandro, Ionna, Franco, Delrio, Paolo, Petrillo, Antonella, Cavalcanti, Ernesta, Di Bonito, Maurizio, Perdonà, Sisto, De Laurentiis, Michelino, Fiore, Francesco, Palaia, Raffaele, Izzo, Francesco, D’Auria, Stefania, Rossi, Virginia, Menegozzo, Simona, Piccirillo, Mauro, Celentano, Egidio, Cuomo, Arturo, Normanno, Nicola, Tornesello, Maria Lina, Saviano, Rocco, Barberio, Daniela, Buonaguro, Luigi, Giannoni, Giovanni, Muto, Paolo, Miscio, Leonardo, Bianchi, Attilio A. M.“…It has not been identified the reason and the molecular mechanisms of the two different patterns of the pulmonary host responses to the virus from a minimal disease in young subjects to a severe distress syndrome (ARDS) in older subjects, particularly those with previous chronic diseases (including diabetes) and cancer. …”
Publicado 2020
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8510por Brar, Rinnie, Sikka, Pooja, Suri, Vikas, Singh, Mini P., Suri, Vanita, Mohindra, Ritin, Biswal, Manisha“…The incidence of maternal systemic complications was high: eight (18.2%) women developed acute kidney injury and two (4.5%) required haemodialysis support; eight (18.2%) women developed ARDS and seven (15.9%) women required ventilatory support; four (9.1%) women developed acute liver failure. 18 (40.9%) women had evidence of shock. …”
Publicado 2021
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8511por María, Fernández-Martínez, Lorena, Martín-Román, María Luz, Fernández-Vázquez, Cristina, Rey-Valcarcel, Dolores, Pérez-Díaz, Fernando, Turégano-Fuentes“…The most common complications were septic shock, pneumonia, and ARDS. ICU care was required in 17% of patients, and was most often required in the SARS-CoV-2-infected group, which also had a higher morbidity and mortality. …”
Publicado 2021
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8512por Napoli, Claudio, Benincasa, Giuditta, Criscuolo, Clelia, Faenza, Mario, Liberato, Cinzia, Rusciano, Mariangela“…Clinical symptoms of COVID-19 include fever, cough, and fatigue which may progress to acute respiratory distress syndrome (ARDS). The main hematological laboratory findings associated with the severe form of disease are represented by lymphopenia and eosinopenia which mostly occur in the elderly population characterized by cardiovascular comorbidities and immunosenescence. …”
Publicado 2021
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8513“…While hyperthyroidism can be definitively managed with surgical evacuation of the uterus, severe complications associated with hyperthyroidism in GTD have been reported, including thyroid storm-induced multi-organ failure, ARDS, and pulmonary hypertension. CONCLUSION: Early detection of GTD is critical to prevent development of hyperthyroidism and its associated complications. …”
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8514“…The rate of death of COVID-19 was 2,7% and the pathological characteristics of COVID-19 are very similar to ARDS. There are also discussions on the latest epidemiological changes, clinical manifestations, auxiliary examination and COVID-19 pathological characteristics.…”
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8515por Rashidi, Farid, Barco, Stefano, Kamangar, Farin, Heresi, Gustavo A., Emadi, Ashkan, Kaymaz, Cihangir, Jansa, Pavel, Reis, Abilio, Rashidi, Arash, Taghizadieh, Ali, Rezaeifar, Parisa, Moghimi, Minoosh, Ghodrati, Samad, Mozafari, Abolfazl, Foumani, Ali Alavi, Tahamtan, Ouria, Rafiee, Effat, Abbaspour, Zahra, Khodadadi, Kasra, Alamdari, Golsa, Boodaghi, Yasman, Rezaei, Maryam, Muhammadi, Muhammad Javad, Abbasi, Meysam, Movaseghi, Fatemeh, Koohi, Ata, Shakourzad, Leila, Ebrahimi, Fatemeh, Radvar, Sarvin, Amoozadeh, Maryam, Fereidooni, Fatemeh, Naseari, Hanieh, Movalled, Kobra, Ghorbani, Ozra, Ansarin, Khalil“…There was no evidence of acute respiratory distress syndrome (ARDS) in these patients. Other deaths after hospital discharge included myocardial infarction (n = 13), heart failure (n = 9), and stroke (n = 9). …”
Publicado 2021
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8516por Abdeen, Yazan, Kaako, Ahmad, Alnabulsi, Mohammad, Okeh, Amira, Meng, William, Miller, Richard“…Elevation of brain natriuretic peptide (BNP) or NT-proBNP is associated with worse outcomes among patients with Acute Respiratory Distress Syndrome (ARDS). We conducted a retrospective cohort study based on a comprehensive review of Electronic Medical Records (EMRs) of patients with Coronavirus Disease 2019 (COVID-19) to evaluate whether BNP on admission has prognostic value on mortality and hospital length of stay (LOS) among patients admitted with confirmed COVID-19 along with the inclusion of additional prognostic variables. …”
Publicado 2021
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8517por Gómez, Ana María, Henao, Diana Cristina, Muñoz, Oscar Mauricio, Aschner, Pablo, Yepes, Carlos Augusto, Jojoa, Ruby, Kerguelen, Alfonso, Parra, Darío, Jaramillo, Pablo, Umpierrez, Guillermo E.“…Outcome of interest were time in range [TIR], time above [TAR] and below [TBR] range, glycemic variability [coefficient of variation [% CV]), and differences in a composite of complications including ICU admission, acute respiratory distress syndrome (ARDS) and acute kidney injury. RESULTS: A total of 60 patients were included (44 known diabetes and 16 new onset hyperglycemia). …”
Publicado 2021
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8518por Etzrodt, Valerie, Idowu, Temitayo O., Schenk, Heiko, Seeliger, Benjamin, Prasse, Antje, Thamm, Kristina, Pape, Thorben, Müller-Deile, Janina, van Meurs, Matijs, Thum, Thomas, Garg, Ankita, Geffers, Robert, Stahl, Klaus, Parikh, Samir M., Haller, Hermann, David, Sascha“…Translationally, MIR155 was detectable at high levels in bronchoalveolar fluid of patients with ARDS compared to healthy human subjects. CONCLUSIONS: We found that MIR155 is upregulated in the endothelium in mouse and men as part of a systemic inflammatory response and might contribute to the pathophysiology of vascular leakage in a Claudin-1-dependent manner. …”
Publicado 2021
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8519por Hendricks, Candice Laverne, Herd, Candice, Nel, Marcel, Tintinger, Gregory, Pepper, Michael Sean“…Due to the high mortality rates in patients receiving invasive ventilation, practice has changed from “early-intubation” for acute respiratory distress syndrome (ARDS) to a trial of non-invasive ventilation (NIV) or high flow nasal cannula (HFNC) oxygen. …”
Publicado 2021
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8520por Pan, Pan, Su, Longxiang, Wang, Xiaoting, Chai, Wenzhao, Liu, Dawei, Song, Licheng, Xie, Lixin“…BACKGROUND: The activation and assembly of the NLRP3 inflammasome is dependent on the interaction between NLRP3 and the intermediate filament protein vimentin in an acute respiratory distress syndrome (ARDS) model. We investigated the role of vimentin in this process using human fetal lung (HFL-1) fibroblasts with vimentin transfer genes or gene knockdown and lipopolysaccharide (LPS) intervention. …”
Publicado 2021
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