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  1. 8541
    “…SARS-CoV-2 primarily targets the lung tissue by causing diffuse alveolar damage and may result in Acute Respiratory Distress Syndrome (ARDS). SARS-CoV-2 infects the cell via cell surface receptor, angiotensin-converting enzyme 2 (ACE2). …”
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    A mini-review on the impact of COVID 19 on vital organs
  2. 8542
    “…Coronavirus disease-2019 (COVID-19) associated pneumonia may progress into acute respiratory distress syndrome (ARDS). Some patients develop features of macrophage activation syndrome (MAS). …”
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    Tocilizumab treatment in severe COVID-19: a multicenter retrospective study with matched controls
  3. 8543
    “…Advanced extracorporeal respiratory techniques offer real survival opportunities to patients with severe influenza-related ARDS. The presence of coinfection should be considered in patients with influenza and respiratory failure. …”
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    Influenza in patients with respiratory failure admitted to intensive care units in Poland and the use of extracorporeal respiratory support: a survey-based multicenter study
  4. 8544
    “…The negative impact may be worsened when significant lung non-homogeneity is present, eg. ALI and ARDS. Protective lung strategies to minimize VILI are to use low tidal volumes (Vt 4–6 mL/kg/PBW), plateau pressures (P(plat)) <30 cmH(2)O and relatively high positive end-expiratory pressures (PEEP). …”
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    Programmed Multi-Level Ventilation: A Strategy for Ventilating Non-Homogenous Lungs
  5. 8545
    “…Recent work has highlighted proinflammatory neutrophil phenotypes contributing to lung injury and acute respiratory distress syndrome (ARDS) in patients with coronavirus disease 2019 (COVID-19). …”
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    Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19
  6. 8546
    “…METHODS: M., a 45-year-old man, who survived a severe COVID-19 disease course including Acute Respiratory Distress Syndrome (ARDS), cerebral microbleeds, and 35 days of mechanical ventilation, is described. …”
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    Monthlong Intubated Patient with Life-Threatening COVID-19 and Cerebral Microbleeds Suffers Only Mild Cognitive Sequelae at 8-Month Follow-up: A Case Report
  7. 8547
    “…Inflammatory injury is a hallmark of sepsis-induced acute respiratory distress syndrome (ARDS)/acute lung injury (ALI). However, the mechanisms underlying inflammatory injury remain obscure. …”
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    Sirt3 Maintains Microvascular Endothelial Adherens Junction Integrity to Alleviate Sepsis-Induced Lung Inflammation by Modulating the Interaction of VE-Cadherin and β-Catenin
  8. 8548
    “…Around 47% patients had severe ARDS, and 60% patients required invasive mechanical ventilation. 28 day ICU mortality was 50%, with a mortality of 75% in patients receiving invasive mechanical ventilation. …”
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    Epidemiology and clinical characteristics of COVID- 19 patients requiring critical care in a Tertiary care teaching hospital
  9. 8549
    “…Severe Coronavirus disease 2019 (COVID-19) is characterized by acute respiratory distress syndrome (ARDS) which may lead to long-lasting pulmonary sequelae in the survivors. …”
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    Case Report: Nintedaninb May Accelerate Lung Recovery in Critical Coronavirus Disease 2019
  10. 8550
    “…CONCLUSION: Our results showed increased rate of positive cases with fortunately lower mortality rate, although this novel pneumonia was associated with acute respiratory distress syndrome ARDS and intensive care unit (ICU) admission. Timely decisions, risk awareness knowledge and supply of necessary equipments are inevitable for the control of such epidemics.…”
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    Lower mortality rate in health workers and their families infected with COVID-19 associated pneumonia in Quetta, Baluchistan
  11. 8551
    “…Respiratory manifestations of SARS-CoV-2 infection such as acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) leads to hypoxia, oxidative stress, and sympatho-activation and in severe cases leads to sympathetic storm (SS). …”
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    Effects of β-Blockers on the Sympathetic and Cytokines Storms in Covid-19
  12. 8552
    “…Severe COVID-19 is associated with a systemic hyperinflammatory response leading to acute respiratory distress syndrome (ARDS), multi-organ failure, and death. Galectin-3 is a ß-galactoside binding lectin known to drive neutrophil infiltration and the release of pro-inflammatory cytokines contributing to airway inflammation. …”
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    Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients
  13. 8553
    “…METHODS: We used a computational simulator matched to data from 90 patients with acute respiratory distress syndrome (ARDS) to evaluate the accuracy of three “at-the-bedside” methods for estimating ventilator [Formula: see text] during APRV. …”
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    Validation of at-the-bedside formulae for estimating ventilator driving pressure during airway pressure release ventilation using computer simulation
  14. 8554
    “…Acute respiratory distress syndrome (ARDS) and extrapulmonary complications can correlate with prognosis in COVID-19 patients. …”
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    Association of systemic complications with mortality in coronavirus disease of 2019: A cohort study on intensive care unit patients
  15. 8555
    “…Some patients suffering from the new Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) develop an exaggerated inflammatory response triggered by a “cytokine storm” resulting in acute respiratory distress syndrome (ARDS) with the concomitant activation of non-specific inflammatory reactivity in the circulatory system and other organs, leading to multiorgan failure, leaky vasculature, coagulopathies and stroke. …”
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    Immunoregulation of Ghrelin in neurocognitive sequelae associated with COVID-19: an in silico investigation
  16. 8556
    “…Since COVID-19 has emerged as a word public health problem, attention has been focused on how immune-suppressive drugs used for the treatment of autoimmune disorders influence the risk for SARS-CoV-2 infection and the development of acute respiratory distress syndrome (ARDS). Here, we discuss the disease-modifying agents approved for the treatment of multiple sclerosis (MS) within this context. …”
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    Drugs Used in the Treatment of Multiple Sclerosis During COVID-19 Pandemic: A Critical Viewpoint
  17. 8557
    “…Fifth, we report long-lasting pulmonary consequences of ARDS and prolonged mechanical ventilation. Finally, we discuss several specificities in children, including the influence of the child’s pre-ICU condition, development, and maturation. …”
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    Chronic critical illness and post-intensive care syndrome: from pathophysiology to clinical challenges
  18. 8558
    “…Likewise, many hospitalized patients develop severe pneumonia associated with acute respiratory distress syndrome (ARDS), along an exacerbated and uncontrolled systemic inflammation that in some cases induces a fatal cytokine storm. …”
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    Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients
  19. 8559
    “…The coronavirus disease-2019 (COVID-19) is caused by SARS-CoV-2, leading to acute respiratory distress syndrome (ARDS), thrombotic complications, and myocardial injury. …”
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    The Effect of Statins on Clinical Outcome Among Hospitalized Patients With COVID-19: A Multi-Centric Cohort Study
  20. 8560
    “…CONCLUSION: This case of TRALI, following transfusion of a single unit of SDP to a patient without ARDS risk factors, demonstrates that TRALI can occur with this product. …”
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    Reported transfusion‐related acute lung injury associated with solvent/detergent plasma – A case series
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