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Mostrando 401 - 420 Resultados de 7,224 Para Buscar '"ARN"', tiempo de consulta: 0.29s Limitar resultados
  1. 401
    “…A case report of a 68-year-old male who developed acute retinal necrosis (ARN) after Boston type I keratoprosthesis is presented. …”
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    Acute Retinal Necrosis after Boston Type I Keratoprosthesis
  2. 402
    “…RESULTS: The eight colistin-resistant K. pneumoniae isolates belonged to three different clones (ST11, 14 and 231). The eptA and arnT genes from lipid modification pathway had novel (R157S in arnT and Q319R in eptA) and rare mutations (V39L, R152H, S260L and A279G in eptA). …”
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    Multiple mutations in lipid-A modification pathway & novel fosA variants in colistin-resistant Klebsiella pneumoniae
  3. 403
    “…Remarkably, although ARN5187 and chloroquine share similar lysosomotropic potency and have a similar effect on autophagy inhibition, ARN5187 is significantly more cytotoxic. …”
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    Dual inhibition of REV-ERBβ and autophagy as a novel pharmacological approach to induce cytotoxicity in cancer cells
  4. 404
    “…Significant effects were observed between conditions in the right affective and reward network (ARN), the right fronto parietal network (FPN) and the sensorimotor network (SMN). …”
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    Modulation of Distinct Intrinsic Resting State Brain Networks by Acute Exercise Bouts of Differing Intensity
  5. 405
    “…Here, we directed overexpression of each arn operon by genomic insertion of inducible promoters. …”
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    A Burkholderia thailandensis DedA Family Membrane Protein Is Required for Proton Motive Force Dependent Lipid A Modification
  6. 406
    “…PURPOSE: The aim of this study was to evaluate the anatomic and functional outcomes of 25-gauge pars plana vitrectomy (25G PPV) with encircling scleral band (ESB) in patients with acute retinal necrosis (ARN)-related rhegmatogenous retinal detachment (RRD). …”
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    Outcomes of 25-gauge pars plana vitrectomy with encircling scleral band for acute retinal necrosis-related rhegmatogenous retinal detachment
  7. 407
    “…The arnT mRNA expression levels were determined by reverse transcription quantitative PCR. …”
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    High prevalence of colistin heteroresistance in specific species and lineages of Enterobacter cloacae complex derived from human clinical specimens
  8. 408
    “…Expression of neuropeptides was quantified by RT-qPCR in micro-dissected RP3V and ARN tissue from a separate cohort of adult PNA and VEH mice (n=5-8/group). …”
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    FRI278 Kisspeptin Neuron Projections And Expression Patterns Are Unaltered In Prenatally Androgenized Female Mice Modeling PCOS
  9. 409
    “…Anticoagulant-related nephropathy (ARN) is a rare, newly recognized cause of acute kidney injury and significant but underdiagnosed complication of anticoagulation therapy. …”
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    Warfarin Related Kidney Damage: A Confusing Case of Thrombophlebitis Masquerading as Infection
  10. 410
    “…During its transport to the bacterial surface, the phosphate groups of the lipid A anchor of Escherichia coli and Salmonella lipopolysaccharide are modified by membrane enzymes including ArnT, EptA and LpxT. ArnT and EptA catalyse the periplasmic addition of the positively charged substituents 4-amino-4-deoxy-L-arabinose and phosphoethanolamine respectively. …”
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    Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides
  11. 411
    “…Here, we report a mechanistic study that clarifies key aspects of the dual inhibition of the fatty acid amide hydrolase (FAAH) and the cyclooxygenase (COX) enzymes by a new multitarget‐directed ligand named ARN2508 (2‐[3‐fluoro‐4‐[3‐(hexylcarbamoyloxy)phenyl]phenyl]propanoic acid). …”
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    The Molecular Basis for Dual Fatty Acid Amide Hydrolase (FAAH)/Cyclooxygenase (COX) Inhibition
  12. 412
    “…We also propose using descriptors scaled by the sum of #ArN and #BaN (SBAN) to define an antimalarial property space. …”
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    Physicochemical Profiling and Comparison of Research Antiplasmodials and Advanced Stage Antimalarials with Oral Drugs
  13. 413
    “…RESULTS: Forty-one patients with NHR were included: 59% with ARN, 7% with PORN, and 34% with CMV retinitis. All patients with CMV retinitis and PORN were immunocompromised versus 21% of patients with ARN. …”
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    First-line management of necrotizing herpetic retinitis by prioritizing the investigation of immune status and prognostic factors for poor visual outcomes
  14. 414
    “…Ocular toxoplasmosis and ARN were also common causes of infectious uveitis. …”
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    Infectious uveitis in Virginia
  15. 415
    “…In the present study we investigated whether the HSV-1/2 glycoprotein B-specific antibody mAb 2c or its humanized counterpart mAb hu2c can protect from ocular disease in a mouse model of HSV-1-induced acute retinal necrosis (ARN). In this model the viral spread from the initially infected to the contralateral eye resembles the routes taken in humans upon HSV reactivation. …”
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    A Therapeutic Antiviral Antibody Inhibits the Anterograde Directed Neuron-to-Cell Spread of Herpes Simplex Virus and Protects against Ocular Disease
  16. 416
    “…Anticoagulant-related nephropathy (ARN) was initially described in patients on warfarin (as warfarin-related nephropathy) and recently in those using dabigatran. …”
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    Acute kidney injury aggravated by treatment initiation with apixaban: Another twist of anticoagulant-related nephropathy
  17. 417
    “…Neuronal nitric oxide synthase (nNOS) catalyzes single-electron reduction of quinones (Q), nitroaromatic compounds (ArNO(2)) and aromatic N-oxides (ArN → O), and is partly responsible for their oxidative stress-type cytotoxicity. …”
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    Reactions of Recombinant Neuronal Nitric Oxide Synthase with Redox Cycling Xenobiotics: A Mechanistic Study
  18. 418
    “…3-Amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ) and other heteroaromatic N-oxides (ArN→O) exhibit tumoricidal, antibacterial, and antiprotozoal activities. …”
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    Redox Proteomic Profile of Tirapazamine-Resistant Murine Hepatoma Cells
  19. 419
    “…PURPOSE: To describe the rare entity of concurrent herpetic acute retinal necrosis (ARN) and orbital inflammation. OBSERVATIONS: Two cases of ARN with simultaneous orbital inflammation are described. …”
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    Concurrent acute retinal necrosis and orbital inflammation: Report of 2 cases
  20. 420
    “…We identified a potent lead compound [compound 14 (ARN-21934) IC(50) = 2 μM for inhibition of DNA relaxation, as compared to an IC(50) = 120 μM for the anticancer drug etoposide] with excellent metabolic stability and solubility. …”
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    Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β
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