-
201por Yamamoto, Kentaro, Tamai, Rei, Yamazaki, Megumi, Inaba, Takehiko, Sowa, Yoshiyuki, Kawagishi, Ikuro“…The only constitutively expressed RND system of Escherichia coli consists of the inner membrane transporter AcrB, the membrane fusion protein AcrA, and the outer membrane channel TolC. The latter two components are shared with another RND-type transporter AcrD, whose expression is induced by environmental stimuli. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
202por Fang, Li, Chen, Qiong, Shi, Keren, Li, Xi, Shi, Qiucheng, He, Fang, Zhou, Jiancang, Yu, Yunsong, Hua, Xiaoting“…A transcriptome analysis demonstrated high expression of the ramR operon and acrA in all tigecycline-resistant strains. Genes involved in nitrogen metabolism were induced in the laboratory-evolved strains compared with the wild-type and clinical strains, and this difference in nitrogen metabolism reflected the variation between the laboratory-evolved and the clinical strains. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
203por Shi, Xiaodong, Chen, Muyuan, Yu, Zhili, Bell, James M., Wang, Hans, Forrester, Isaac, Villarreal, Heather, Jakana, Joanita, Du, Dijun, Luisi, Ben F., Ludtke, Steven J., Wang, Zhao“…We also observe intermediate AcrAB complexes without TolC and discover that AcrA contacts the peptidoglycan layer of the periplasm. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
204
-
205
-
206por Chia, Audrey Qi Xin, Cheng, Lionel Tim-Ee, Wijaya, Limin, Png, Meng Ai, Sim, Wei Yow, Hong, Wei Liang, Chen, Robert ChunEnlace del recurso
Publicado 2020
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
207por Wang, Gary X., Chou, Shinn-Huey S., Lamb, Leslie R., Narayan, Anand K., Dontchos, Brian N., Lehman, Constance D., Miles, Randy C.Enlace del recurso
Publicado 2021
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
208
-
209“…Then, the MIC of different combinations of honey, ciprofloxacin, and plant alkaloid extract and expression of acrA and soxS genes were carried out using the agar dilution method and quantitative RT- PCR methods. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
210por Otoupal, Peter B., Eller, Kristen A., Erickson, Keesha E., Campos, Jocelyn, Aunins, Thomas R., Chatterjee, Anushree“…Finally, these results informed the design of four antisense peptide nucleic acid (PNA) co-therapies, csgD, fnr, recA and acrA, against four MDR, clinically isolated bacteria. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
211
-
212por Boyer, Esther, Dessolin, Jean, Lustig, Margaux, Decossas, Marion, Phan, Gilles, Cece, Quentin, Durand, Grégory, Dubois, Véronique, Sansen, Joris, Taveau, Jean-Christophe, Broutin, Isabelle, Daury, Laetitia, Lambert, Olivier“…Structures of MexA–MexB–OprM and AcrA–AcrB–TolC, from Pseudomonas aeruginosa and Escherichia coli, respectively, depict a reduced interfacial contact between OMF and PAP, making unclear the comprehension of how OMF is recruited. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
213por Tran, My Trung, Vu, Duc Minh, Vu, Manh Duy, Bui, My Thi Phuong, Dang, Binh Xuan, Dang, Lan Thi Mai, Le, Thien Van“…CONCLUSIONS: Klebsiella spp. associated with bovine mastitis in Nghe An province were mostly multidrug-resistant and carried virulence genes including fimH, entB, and antimicrobials resistant genes (bla(SHV), acrA(Kp), tetA, etc.), but these isolates were not ESBL producers.…”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
214“…A non-significant increase in acrA, acrB, and tolC expression in response to prolonged exposure to PAβN was noted in cells treated with PAβN alone or with AZT, as a reflection of bacterial attempts to counteract pump inhibition. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
215por Ihssen, Julian, Kowarik, Michael, Dilettoso, Sandro, Tanner, Cyril, Wacker, Michael, Thöny-Meyer, Linda“…RESULTS: Two different periplasmic carrier proteins, AcrA from C. jejuni and a toxoid form of Pseudomonas aeruginosa exotoxin were glycosylated with Shigella O antigens in E. coli. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
216“…Through employing a labile mutant periplasmic protein, AcrA(L222Q), it was determined that the rpoE3 mutation overcomes the ΔdegP phenotypes, in part, by activating a σ(E)-dependent proteolytic pathway. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
217por Ledger, Araminta E.W., Borri, Marco, Pope, Romney J.E., Scurr, Erica D., Wallace, Toni, Richardson, Cheryl, Usher, Marianne, Allen, Steven, Wilson, Robin M., Thomas, Karen, deSouza, Nandita M., Leach, Martin O., Schmidt, Maria A.Enlace del recurso
Publicado 2014
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
218“…To investigate the efflux-mediated resistance mechanisms of K. pneumoniae, the expression of efflux pump genes (acrA, acrB, tolC, oqxA and oqxB) and pump regulators (acrR, marA, soxS, rarA, rob and ramA) were examined by real-time RT-PCR. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
219por Chakrabarty, Ram Prosad, Sultana, Munawar, Shehreen, Saadlee, Akter, Selina, Hossain, M. Anwar“…SBH confirmed 7 isolates harbored qnrS gene in plasmids. The acrA, acrB and tolC were present in all 18 isolates and NMP had an additive (12-isolates) or synergistic (6-isolates) effect on CIP action. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
220por Ramaswamy, Venkata Krishnan, Vargiu, Attilio V., Malloci, Giuliano, Dreier, Jürg, Ruggerone, Paolo“…Resistance-Nodulation-cell Division (RND) transporters AcrB and AcrD of Escherichia coli expel a wide range of substrates out of the cell in conjunction with AcrA and TolC, contributing to the onset of bacterial multidrug resistance. …”
Publicado 2017
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto