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301por Swetha, Thirukannamangai Krishnan, Pooranachithra, Murugesan, Subramenium, Ganapathy Ashwinkumar, Divya, Velayutham, Balamurugan, Krishnaswamy, Pandian, Shunmugiah Karutha“…Furthermore, real time PCR analysis revealed the reduced expression of adhesion encoding genes (icaD, atlE, aap, bhp, ebh, sdrG, and sdrF). Down regulation of agrA and reduced production of secreted hydrolases upon UMB treatment were speculated to hinder invasive lifestyle of MRSE. …”
Publicado 2019
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302por Wang, Jinli, Jiao, Haihong, Meng, Jinwu, Qiao, Mingyu, Du, Hongxu, He, Miao, Ming, Ke, Liu, Jiaguo, Wang, Deyun, Wu, Yi“…These results showed that baicalin decreased biofilm formation, inhibited bacterial aggregation, and downregulated mRNA transcription levels of the quorum-sensing system regulators agrA, agrC, RNAIII, and sarA. Correlation analysis indicated that there was a strong positive correlation between the efflux pump and biofilm formation and the agr system. …”
Publicado 2019
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303por Gautam, Alok Sagar, Dilwaliya, Nikhilesh Kumar, Srivastava, Ayushi, Kumar, Sanjeev, Bauddh, Kuldeep, Siingh, Devendraa, Shah, M. A., Singh, Karan, Gautam, Sneha“…So, we studied the differences in the air quality index (AQI) of Delhi (DTU, Okhla and Patparganj), Haryana (Jind, Palwal and Hisar) and Uttar Pradesh (Agra, Kanpur and Greater Noida) from 17 February 2020 to 4 May 2020. …”
Publicado 2020
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304por Peng, Jian, Mishra, Biswajit, Khader, Rajamohammed, Felix, LewisOscar, Mylonakis, Eleftherios“…Besides, C18 possessed a strong binding ability with DNA at 7.8 μM and down-regulated the expression of virulence factor genes like agrA, fnb-A, and clf-1 by more than 5-fold (p < 0.05). …”
Publicado 2021
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305por Liu, Yunge, Wu, Lina, Han, Jina, Dong, Pengcheng, Luo, Xin, Zhang, Yimin, Zhu, Lixian“…Supporting these findings, expression analysis showed that all four natural compounds at 1/4 × MIC significantly down-regulated quorum sensing genes (agrA, agrC, and agrD) rather than suppressing the motility- and flagella-associated genes (degU, motB, and flaA). …”
Publicado 2021
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306por Dotto, Cristian, Lombarte Serrat, Andrea, Ledesma, Martín, Vay, Carlos, Ehling-Schulz, Monika, Sordelli, Daniel O., Grunert, Tom, Buzzola, Fernanda“…In silico docking and simulation of molecular dynamics provided evidence for a potential interaction of AgrA and SAL, resulting in reduced activity of the agr system. …”
Publicado 2021
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307por Liu, Yansong, Shi, Yiyi, Cheng, Hang, Chen, Junwen, Wang, Zhanwen, Meng, Qingyin, Tang, Yuanyuan, Yu, Zhijian, Zheng, Jinxin, Shang, Yongpeng“…Using quantitative reverse transcription PCR, we found that the RNA levels of transcriptional regulatory genes (RNAIII, agrA, agrC, saeR, and saeS), biofilm-formation-related genes (atl, cidA, clfA, clfB, and icaA), and virulence-related genes (cap5A, hla, hld, hlg, lukDE, lukpvl-S, staphopain B, alpha-3 PSM, beta PSM, and delta PSM) of S. aureus decreased after 6 h treatment with lapatinib. …”
Publicado 2022
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308por Jo, Sung-Hyun, Song, Won-Suk, Park, Han-Gyu, Lee, Jae-Seung, Jeon, Hyo-Jin, Lee, Yeon-Hee, Kim, Wooseong, Joo, Hwang-Soo, Yang, Yung-Hun, Kim, Jae-Seok, Kim, Yun-Gon“…The quantitative proteomics demonstrated that proteins involved in peptidoglycan biosynthesis (MurZ, PBP2, SgtB, PrsA), two-component systems (VrsSR, WalR, SaeSR, AgrA), oxidative stress (MsrA1, MsrB), and stringent response (RelQ) were differentially regulated after the oxacillin treatment of the isogenic isolates. …”
Publicado 2020
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309“…METHODOLOGY: Questionnaires were made available to all willing doctors of SN Medical College, Agra; King George's Medical University, Lucknow, and GSVM Medical College, Kanpur, between May 12, 2020, and June 20, 2020 (during nationwide lockdown). …”
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310por Yu, Hangqian, Liu, Jingyu, Wang, Li, Guan, Shuhan, Jin, Yajing, Zheng, Jianze, Xiang, Hua, Wang, Dacheng, Liu, Dianfeng“…RT-qPCR and western blot revealed that 2,3-DHKV suppressed Hla expression at the mRNA and protein levels, and further decreased accessory gene regulator A (agrA) transcription levels. We also observed that 2,3-DHK significantly attenuated the damage of A549 cells by S. aureus and reduced the release of lactate dehydrogenase (LDH). …”
Publicado 2022
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311por Cella, Monica Angela, Coulson, Thomas, MacEachern, Samantha, Badr, Sara, Ahmadi, Ali, Tabatabaei, Mahdis Sadat, Labbe, Alain, Griffiths, Mansel William“…Real-time quantitative PCR analysis of the QS-genes agrA and luxS, showed differential expression between MRSA strains, and a significant downregulation of the hemolysin gene hla. …”
Publicado 2023
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312por Tingting, Sun, Xinyue, Feng, Tiantian, Yang, xiao, An, Rui, Li, Feng, Lin, Daohong, Liu, Zhirui, Li, Guoqi, Wang“…The expression levels of agrA, Eap, Spa, and Hla genes of the NPWTi group were significantly lower than that of the NPWT group on day 8 (P < 0.05). …”
Publicado 2023
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313por Martínez, Andrés, Stashenko, Elena E., Sáez, Rodrigo Torres, Zafra, German, Ortiz, Claudia“…In addition, this effect was also determined in S. aureus where the L. origanoides EO diminished the expression of genes involved in QS communication (agrA), production of exopolysaccharides by PIA/PNG (icaA), synthesis of alpha hemolysin (hla), transcriptional regulators of the production of extracellular toxins (RNA III), QS and biofilm formation transcriptional regulators (sarA) and global regulators of biofilm formation (rbf and aur). …”
Publicado 2023
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314por Qin, Junyuan, Yu, Lei, Peng, Fu, Ye, Xin, Li, Gangmin, Sun, Chen, Cheng, Fang, Peng, Cheng, Xie, Xiaofang“…Examining the expression of icaA, cidA, sigB, agrA, and sarA genes in MRSA, we discovered that TPCP inhibited biofilm formation by affecting the quorum-sensing system in bacteria. …”
Publicado 2023
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315por Othman, Amal S., Shamekh, Israa M., Abdalla, Mohnad, Eltayb, Wafa A., Ahmed, Nashwa A.“…Molecular docking analysis was conducted to confirm the impact of curcumin on the most vital and positively identified quorum-sensing pathway signaling proteins SecA-SecY, LsrR, PqsR (MvfR), AgrA which act as key players in the bacterial communication systems. …”
Publicado 2023
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316por Kaushik, Nupur, Rani, Deepa, Agarwal, Pooja, Kumar, Harendra, Kumar, Lalit, Singh, Akhil Pratap“…MATERIAL AND METHODS: The study was a retrospective study conducted in the Department of Pathology, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India, over four months from April 2021 to July 2021, and clinically diagnosed mucormycosis cases were included in this study. …”
Publicado 2023
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317por Dabash, Rasha, Vajpayee, Jyoti, Jacob, Martha, Dzuba, Ilana, Lal, Nisha, Bradley, Jan, Prasad, LB“…In an effort to assess the need and potential for improving the quality of cervical cancer prevention and treatment services in Uttar Pradesh, a strategic assessment was conducted in three of the state's districts: Agra, Lucknow, and Saharanpur. METHODS: Using an adaptation of stage one of the World Health Organization's Strategic Approach to Improving Reproductive Health Policies and Programmes, an assessment of the quality of cervical cancer services was carried out by a multidisciplinary team of stakeholders. …”
Publicado 2005
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318por Song, Yang, Rubio, Aileen, Jayaswal, Radheshyam K., Silverman, Jared A., Wilkinson, Brian J.“…Both strains had the same mutations in the two-component system genes walK and agrA. In strain CB1540 mutations were also detected in the ribose phosphate pyrophosphokinase (prs) and polyribonucleotide nucleotidyltransferase genes (pnpA), a hypothetical protein gene, and in an intergenic region. …”
Publicado 2013
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319Dissecting Vancomycin-Intermediate Resistance in Staphylococcus aureus Using Genome-Wide Associationpor Alam, Md Tauqeer, Petit, Robert A., Crispell, Emily K., Thornton, Timothy A., Conneely, Karen N., Jiang, Yunxuan, Satola, Sarah W., Read, Timothy D.“…The model predicted VISA based on the presence of a rare mutation in a set of candidate genes (walKR, vraSR, graSR, and agrA) and/or three previously experimentally verified mutations (including the rpoB H481 locus) with an accuracy of 81% and a sensitivity of 73%. …”
Publicado 2014
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320por Chen, Yan, Liu, Tangjuan, Wang, Ke, Hou, Changchun, Cai, Shuangqi, Huang, Yingying, Du, Zhongye, Huang, Hong, Kong, Jinliang, Chen, Yiqiang“…Most strikingly, real-time qualitative polymerase chain reaction data demonstrated that 32 μg/mL and 64 μg/mL baicalein downregulated the quorum-sensing system regulators agrA, RNAIII, and sarA, and gene expression of ica, but 16 μg/mL baicalein had no effect. …”
Publicado 2016
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