Mitochondrial ROS Triggers KIN Pathogenesis in FAN1-Deficient Kidneys

por Airik, Merlin, Arbore, Haley, Childs, Elizabeth, Huynh, Amy B., Phua, Yu Leng, Chen, Chi Wei, Aird, Katherine, Bharathi, Sivakama, Zhang, Bob, Conlon, Peter, Kmoch, Stanislav, Kidd, Kendrah, Bleyer, Anthony J., Vockley, Jerry, Goetzman, Eric, Wipf, Peter, Airik, Rannar
Publicado 2023

Novel Heterozygous Mutation in NFKB2 Is Associated With Early Onset CVID and a Functional Defect in NK Cells Complicated by Disseminated CMV Infection and Severe Nephrotic Syndrome

por Aird, Alejandra, Lagos, Macarena, Vargas-Hernández, Alexander, Posey, Jennifer E., Coban-Akdemir, Zeynep, Jhangiani, Shalini, Mace, Emily M., Reyes, Anaid, King, Alejandra, Cavagnaro, Felipe, Forbes, Lisa R., Chinn, Ivan K., Lupski, James R., Orange, Jordan S., Poli, Maria Cecilia
Publicado 2019

De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression

por Tangudu, Naveen Kumar, Buj, Raquel, Wang, Hui, Wang, Jiefei, Cole, Aidan R., Uboveja, Apoorva, Fang, Richard, Amalric, Amandine, Sajjakulnukit, Peter, Lyons, Maureen A., Cooper, Kristine, Hempel, Nadine, Snyder, Nathaniel W., Lyssiotis, Costas A., Chandran, Uma R., Aird, Katherine M.
Publicado 2023

Down syndrome suppression of tumor growth and the role of the calcineurin inhibitor DSCR1

por Baek, Kwan-Hyuck, Zaslavsky, Alexander, Lynch, Ryan C., Britt, Carmella, Okada, Yoshiaki, Siarey, Richard J., Lensch, M. William, Park, In-Hyun, Yoon, Sam S., Minami, Takashi, Reeves, Roger, Korenberg, Julie R., Folkman, Judah, Daley, George Q., Aird, William C., Galdzicki, Zygmunt, Ryeom, Sandra
Publicado 2009

NAD(+) metabolism governs the proinflammatory senescence-associated secretome

por Nacarelli, Timothy, Lau, Lena, Fukumoto, Takeshi, Zundell, Joseph, Fatkhutdinov, Nail, Wu, Shuai, Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Schultz, David, Noma, Ken-ichi, Baur, Joseph A., Schug, Zachary, Tang, Hsin-Yao, Speicher, David W., David, Gregory, Zhang, Rugang
Publicado 2019

Alternatively activated macrophages promote resolution of necrosis following acute liver injury

por Starkey Lewis, Philip, Campana, Lara, Aleksieva, Niya, Cartwright, Jennifer Ann, Mackinnon, Alison, O'Duibhir, Eoghan, Kendall, Timothy, Vermeren, Matthieu, Thomson, Adrian, Gadd, Victoria, Dwyer, Benjamin, Aird, Rhona, Man, Tak-Yung, Rossi, Adriano Giorgio, Forrester, Lesley, Park, B. Kevin, Forbes, Stuart John
Publicado 2020

Multiple ETS Family Proteins Regulate PF4 Gene Expression by Binding to the Same ETS Binding Site

por Okada, Yoshiaki, Nobori, Haruaki, Shimizu, Mikiko, Watanabe, Miho, Yonekura, Masaaki, Nakai, Tomoko, Kamikawa, Yuko, Wakimura, Atsuko, Funahashi, Nobuaki, Naruse, Hiroki, Watanabe, Ayako, Yamasaki, Daisuke, Fukada, So-ichiro, Yasui, Kazuta, Matsumoto, Kayoko, Sato, Takahiro, Kitajima, Kenji, Nakano, Toru, Aird, William C., Doi, Takefumi
Publicado 2011

A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity

por Yuan, Lei, Chan, Gary C., Beeler, David, Janes, Lauren, Spokes, Katherine C., Dharaneeswaran, Harita, Mojiri, Anahita, Adams, William J., Sciuto, Tracey, Garcia-Cardeña, Guillermo, Molema, Grietje, Kang, Peter M., Jahroudi, Nadia, Marsden, Philip A., Dvorak, Ann, Regan, Erzsébet Ravasz, Aird, William C.
Publicado 2016

MDR1-deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation

por Ho, Gwo-Tzer, Aird, Rhona E, Liu, Bo, Boyapati, Ray K, Kennedy, Nicholas A, Dorward, David A, Noble, Colin L, Shimizu, Takahiko, Carter, Roderick N, Chew, Etienne TS, Morton, Nicholas M, Rossi, Adriano G, Sartor, R. Balfour, Iredale, John P, Satsangi, Jack
Publicado 2017

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

por Worley, Beth L., Kim, Yeon Soo, Mardini, Jennifer, Zaman, Rameez, Leon, Kelly E., Vallur, Piyushi Gupta, Nduwumwami, Asvelt, Warrick, Joshua I., Timmins, Patrick F., Kesterson, Joshua P., Phaëton, Rébécca, Lee, Nam Y., Walter, Vonn, Endres, Lauren, Mythreye, Karthikeyan, Aird, Katherine M., Hempel, Nadine
Publicado 2018

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

por Sui, Jianhua, Hwang, William C, Perez, Sandra, Wei, Ge, Aird, Daniel, Chen, Li-mei, Santelli, Eugenio, Stec, Boguslaw, Cadwell, Greg, Ali, Maryam, Wan, Hongquan, Murakami, Akikazu, Yammanuru, Anuradha, Han, Thomas, Cox, Nancy J, Bankston, Laurie A, Donis, Ruben O, Liddington, Robert C, Marasco, Wayne A
Publicado 2009

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

por Kim, Yeon Soo, Vallur, Piyushi Gupta, Jones, Victoria M., Worley, Beth L., Shimko, Sara, Shin, Dong-Hui, Crawford, LaTaijah C., Chen, Chi-Wei, Aird, Katherine M., Abraham, Thomas, Shepherd, Trevor G., Warrick, Joshua I., Lee, Nam Y., Phaeton, Rebecca, Mythreye, Karthikeyan, Hempel, Nadine
Publicado 2019

ARID1A-mutated ovarian cancers depend on HDAC6 activity

por Bitler, Benjamin G., Wu, Shuai, Park, Pyoung Hwa, Hai, Yang, Aird, Katherine M., Wang, Yemin, Zhai, Yali, Kossenkov, Andrew V., Vara-Ailor, Ana, Rauscher, Frank J, Zou, Weiping, Speicher, David W., Huntsman, David G., Conejo-Garcia, Jose R., Cho, Kathleen R., Christianson, David W., Zhang, Rugang
Publicado 2017

Linking Circulating Serum Proteins with Clinical Outcomes in Esophageal Adenocarcinoma—An Emerging Role for Chemokines

por Donlon, Noel E., Sheppard, Andrew, Davern, Maria, O’Connell, Fiona, Phelan, James J., Power, Robert, Nugent, Timothy, Dinneen, Kate, Aird, John, Greene, John, Nevins Selvadurai, Paul, Bhardwaj, Anshul, Foley, Emma K., Ravi, Narayanasamy, Donohoe, Claire L., Reynolds, John V., Lysaght, Joanne, O’Sullivan, Jacintha, Dunne, Margaret R.
Publicado 2020

Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression

por Sugitani, Norie, Vendetti, Frank P., Cipriano, Andrew J., Pandya, Pinakin, Deppas, Joshua J., Moiseeva, Tatiana N., Schamus-Haynes, Sandra, Wang, Yiyang, Palmer, Drake, Osmanbeyoglu, Hatice U., Bostwick, Anna, Snyder, Nathaniel W., Gong, Yi-Nan, Aird, Katherine M., Delgoffe, Greg M., Beumer, Jan H., Bakkenist, Christopher J.
Publicado 2022

Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators

por Aird, Daniel, Teng, Teng, Huang, Chia-Ling, Pazolli, Ermira, Banka, Deepti, Cheung-Ong, Kahlin, Eifert, Cheryl, Furman, Craig, Wu, Zhenhua Jeremy, Seiler, Michael, Buonamici, Silvia, Fekkes, Peter, Karr, Craig, Palacino, James, Park, Eunice, Smith, Peter G., Yu, Lihua, Mizui, Yoshiharu, Warmuth, Markus, Chicas, Agustin, Corson, Laura, Zhu, Ping
Publicado 2019

Economic evaluation of robot-assisted training versus an enhanced upper limb therapy programme or usual care for patients with moderate or severe upper limb functional limitation d...

por Fernandez-Garcia, Cristina, Ternent, Laura, Homer, Tara Marie, Rodgers, Helen, Bosomworth, Helen, Shaw, Lisa, Aird, Lydia, Andole, Sreeman, Cohen, David, Dawson, Jesse, Finch, Tracy, Ford, Gary, Francis, Richard, Hogg, Steven, Hughes, Niall, Krebs, H I, Price, Christopher, Turner, Duncan, Van Wijck, Frederike, Wilkes, Scott, Wilson, Nina, Vale, Luke
Publicado 2021

Robot assisted training for the upper limb after stroke (RATULS): a multicentre randomised controlled trial

por Rodgers, Helen, Bosomworth, Helen, Krebs, Hermano I, van Wijck, Frederike, Howel, Denise, Wilson, Nina, Aird, Lydia, Alvarado, Natasha, Andole, Sreeman, Cohen, David L, Dawson, Jesse, Fernandez-Garcia, Cristina, Finch, Tracy, Ford, Gary A, Francis, Richard, Hogg, Steven, Hughes, Niall, Price, Christopher I, Ternent, Laura, Turner, Duncan L, Vale, Luke, Wilkes, Scott, Shaw, Lisa
Publicado 2019

Robot Assisted Training for the Upper Limb after Stroke (RATULS): study protocol for a randomised controlled trial

por Rodgers, Helen, Shaw, Lisa, Bosomworth, Helen, Aird, Lydia, Alvarado, Natasha, Andole, Sreeman, Cohen, David L., Dawson, Jesse, Eyre, Janet, Finch, Tracy, Ford, Gary A., Hislop, Jennifer, Hogg, Steven, Howel, Denise, Hughes, Niall, Krebs, Hermano Igo, Price, Christopher, Rochester, Lynn, Stamp, Elaine, Ternent, Laura, Turner, Duncan, Vale, Luke, Warburton, Elizabeth, van Wijck, Frederike, Wilkes, Scott
Publicado 2017

Evaluation of the enhanced upper limb therapy programme within the Robot-Assisted Training for the Upper Limb after Stroke trial: descriptive analysis of intervention fidelity, goa...

por Bosomworth, Helen, Rodgers, Helen, Shaw, Lisa, Smith, Leanne, Aird, Lydia, Howel, Denise, Wilson, Nina, Alvarado, Natasha, Andole, Sreeman, Cohen, David L, Dawson, Jesse, Fernandez-Garcia, Cristina, Finch, Tracy, Ford, Gary A, Francis, Richard, Hogg, Steven, Hughes, Niall, Price, Christopher I, Ternent, Laura, Turner, Duncan L, Vale, Luke, Wilkes, Scott, Krebs, Hermano I, van Wijck, Frederike
Publicado 2020