“…SwiftOrtho uses long k-mers to speed up homology search, while using a reduced amino acid alphabet and spaced seeds to compensate for the loss of sensitivity due to long k-mers. …”
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“…A total of 28 children aged 8 to 15 years with DCD participated in the study with 28 TD age- and gender-matched control participants. They completed the alphabet writing and copy fast tasks from The Detailed Assessment of Speed of Handwriting on a digitizing writing tablet. …”
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“…We introduce a variant of the problem that asks whether there exists a path in a graph that represents a query string with any number of edit operations and we show that is NP-complete, even when labels have length one and in the case the alphabet is binary. Moreover, when it is parameterized by the length of the input string and graph labels have length one, we show that the problem is fixed-parameter tractable and it is unlikely to admit a polynomial kernel. …”
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“…However, there is lack of tools for applying reduced AA alphabets to the identification and visualization of statistically significant motifs. …”
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“…We here demonstrate an efficient and generally applicable posttranscriptional SDSL method for large RNAs using an expanded genetic alphabet containing the NaM-TPT3 unnatural base pair (UBP). …”
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“…Using crossmodal learning, the system is capable of crossmodally recognizing and imagining multimodal information, such as visualizing alphabet letters upon handwritten input, recognizing multimodal visual/smell/taste information or imagining a never-seen picture when hearing its description. …”
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“…We demonstrate its performance and precision using four different input alphabet distribution on different sequence lengths. …”
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“…We derive theorems for the maximal number of motif classes that can simultaneously maintain a certain number of motif-discriminating positions between all pairs of classes in the motif universe, for a given amino acid alphabet. We also calculate the fraction of all protein subsequences that would belong to a motif class if all potential motif classes came into existence. …”
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“…We were part of the assessment team for the most recent CASP experiment, CASP14, where we witnessed an astonishing breakthrough by DeepMind, the leading artificial intelligence laboratory of Alphabet Inc. The models filed by DeepMind's structure prediction team using the program AlphaFold2 were often essentially indistinguishable from experimental structures, leading to a consensus in the community that the structure prediction problem for single protein chains has been solved. …”
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“…This approach is generalizable to expanding the amino‐acid alphabet in a library beyond 25 building blocks.…”
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“…An accelerometer recorded movement from before, during, and after the task (reciting every other letter of the alphabet). Thirty-six balance metrics were calculated for each task condition. …”
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“…Detailed analysis with structural alphabet, the Proteins Blocks (PBs), allowed observing local changes in highly flexible regions. …”
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“…Through careful reading and understanding of all three versions of the book (in Russian, Chinese, and Mongolian (Cyrillic alphabet)), the FPM-listed information of edible plants was categorized using ethnobotanical dependent analysis. …”
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“…We generated a large synthetic dataset of human arm trajectories tracing characters of the Latin alphabet in 3D space, together with muscle activities obtained from a musculoskeletal model and model-based muscle spindle activity. …”
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“…The World Health Organization has given these variants names according to the letters of the Greek Alphabet, starting with the Alpha (B.1.1.7) variant, which emerged in 2020, followed by the Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2), and Omicron (B.1.1.529) variants. …”
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“…Specifically, given a collection [Formula: see text] of d documents, [Formula: see text] over an alphabet of size [Formula: see text] , we extend the r-index with [Formula: see text] additional words to support document listing queries for a pattern [Formula: see text] that occurs in [Formula: see text] documents in [Formula: see text] in [Formula: see text] time and [Formula: see text] space, where w is the machine word size. …”
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“…The proposed method involves multistage processing, comprising a stage for converting the geometry of protein structures into sequences of a structural alphabet using a neural network, a search stage for forming a set of candidate structures, and a refinement stage for calculating the structural alignment and overlap and evaluating the similarity with the starting structure of the search. …”
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“…The BriX fragment database, consisting of fragments from 4 to 14 residues long, was realized through identification of recurrent backbone fragments from a non-redundant set of high-resolution protein structures. BriX contains an alphabet of more than 1,000 frequently observed conformations per peptide length for 6 different variation levels. …”
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“…CONCLUSIONS: In this work we evaluate svmPRAT on several classification and regression problems including disorder prediction, residue-wise contact order estimation, DNA-binding site prediction, and local structure alphabet prediction. svmPRAT has also been used for the development of state-of-the-art transmembrane helix prediction method called TOPTMH, and secondary structure prediction method called YASSPP. …”
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“…We have developed BS Seeker, an approach that converts the genome to a three-letter alphabet and uses Bowtie to align bisulfite-treated reads to a reference genome. …”
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