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Enfermedad de Alzheimer
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62por Weksler, Marc E“…Only a small percentage of patients with Alzheimer's disease benefit from current drug therapy and for only a relatively short time. …”
Publicado 2004
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63“…Alzheimer's disease (AD) and osteoporosis are both common degenerative diseases in the elderly population. …”
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64“…Proliferation and activation of microglia in the brain, concentrated around amyloid plaques, is a prominent feature of Alzheimer’s disease (AD). Human genetics data point to a key role for microglia in the pathogenesis of AD. …”
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65por Cappa, Stefano F.“…This mini-review considers three different approaches to the therapy and prevention of Alzheimer’s disease (AD): replacement therapy, disease modification, and multi-level interventions. …”
Publicado 2018
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66“…Apathy is the most common neuropsychiatric symptom in patients with Alzheimer's disease (AD). The presence of apathy has been related to greater caregiver distress, decreased quality of life, and increased morbidity. …”
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67por Koch, Manja, DeKosky, Steven T., Fitzpatrick, Annette L., Furtado, Jeremy D., Lopez, Oscar L., Kuller, Lewis H., Mackey, Rachel H., Hughes, Timothy M., Mukamal, Kenneth J., Jensen, Majken K.“…DISCUSSION: Apolipoproteins may be important minimally invasive biomarkers indicative of Alzheimer's pathology.…”
Publicado 2018
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68por Lehrer, Steven“…BACKGROUND: Cancer mortality and Alzheimer’s disease (AD) mortality increase with age, but some studies have shown an inverse relationship of the two diseases, that is, older persons with cancer have a reduced risk of AD and vice versa. …”
Publicado 2018
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69por Kim, Jong Hun“…Alzheimer's disease (AD) related genes have been elucidated by advanced genetic techniques. …”
Publicado 2018
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70“…The term, ‘Alzheimer's disease’ has been used for over 100 years since first used in 1910. …”
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71“…In the hope of future treatments to prevent or slow down the disease, there is a strong movement towards an ever‐earlier detection of Alzheimer’s disease (AD). In conjunction with scientific developments, this has prompted a reconceptualization of AD, as a slowly progressive pathological process with a long asymptomatic phase. …”
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72por Rimmer, Elizabeth“…Alzheimer’s Disease International (ADI) is the international federation of 75 Alzheimer associations throughout the world and is in official relations with the World Health Organization. …”
Publicado 2006
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73“…The brain is highly enriched in lipids, and disruption of lipid homeostasis is related to neurologic disorders as well as neurodegenerative diseases such as Alzheimer’s disease (AD). Aging is associated with changes in lipid composition. …”
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75“…Alzheimer's disease is the most common neurodegenerative disorder, and its prevalence increases with age. …”
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76por Ballard, Clive, Kales, Helen C., Lyketsos, Constantine, Aarsland, Dag, Creese, Byron, Mills, Roger, Williams, Hilde, Sweet, Robert A.“…PURPOSE OF REVIEW: To review the incidence, treatment and genetics of psychosis in people with mild cognitive impairment (MCI) and Alzheimer’s disease (AD). RECENT FINDINGS: Psychosis in Alzheimer’s disease (AD) has an incidence of ~ 10% per year. …”
Publicado 2020
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77por Arroyo-Anlló, Eva Mª, Souchaud, Corinne, Ingrand, Pierre, Chamorro Sánchez, Jorge, Melero Ventola, Alejandra, Gil, Roger“…Several studies have linked alexithymia to cognitive functioning, observing greater alexithymia scores associated with poorer cognitive abilities. Despite Alzheimer’s disease (AD) being a neurodegenerative pathology characterized by cognitive troubles from the early stages, associated to behavioral and emotional disturbances, very few investigations have studied the alexithymia in AD. …”
Publicado 2020
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78por Sansores-España, Daniel, Carrillo-Avila, Arelly, Melgar-Rodriguez, Samanta, Díaz-Zuñiga, Jaime, Martínez-Aguilar, Victor“…BACKGROUND: Alzheimer's disease (AD), the main cause of dementia in the adult population, is characterized by a progressive loss of cognitive function. …”
Publicado 2021
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79“…However, our review of the current literature suggests that under certain conditions, excess levels of propionate may play a role in Alzheimer’s disease (AD). The cause of the excessive levels of propionate may be related to the Bacteroidetes phylum, which are the primary producers of propionate in the human gut. …”
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80por Nikolac Perkovic, Matea, Videtic Paska, Alja, Konjevod, Marcela, Kouter, Katarina, Svob Strac, Dubravka, Nedic Erjavec, Gordana, Pivac, Nela“…There are currently no validated biomarkers which can be used to accurately diagnose Alzheimer’s disease (AD) or to distinguish it from other dementia-causing neuropathologies. …”
Publicado 2021
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