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6641por Deo, Rahul C., Reich, David, Tandon, Arti, Akylbekova, Ermeg, Patterson, Nick, Waliszewska, Alicja, Kathiresan, Sekar, Sarpong, Daniel, Taylor, Herman A., Wilson, James G.“…To address this problem for cardiovascular phenotypes, we studied a cohort of 4,464 African Americans from the Jackson Heart Study (JHS), in whom we genotyped both a panel of 12 recently discovered genetic variants known to predict lipid profile levels in Europeans and a panel of up to 1,447 ancestry informative markers allowing us to determine the African ancestry proportion of each individual at each position in the genome. …”
Publicado 2009
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6642por Kelley, James M., Hughes, Laura B., Faggard, Jeffrey D., Danila, Maria I., Crawford, Monica H., Edberg, Yuanqing, Padilla, Miguel A., Tiwari, Hemant K., Westfall, Andrew O., Alarcón, Graciela S., Conn, Doyt L., Jonas, Beth L., Callahan, Leigh F., Smith, Edwin A., Brasington, Richard D., Allison, David B., Kimberly, Robert P., Moreland, Larry W., Edberg, Jeffrey C., Bridges, S. Louis“…We sought to determine if CTLA4 polymorphisms are associated with RA in African Americans. We performed a 2-stage analysis of 12 haplotype tagging single nucleotide polymorphisms (SNPs) across CTLA4 in a total of 505 African American RA patients and 712 African American controls using Illumina and TaqMan platforms. …”
Publicado 2009
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6643por Cheng, Ching-Yu, Kao, W. H. Linda, Patterson, Nick, Tandon, Arti, Haiman, Christopher A., Harris, Tamara B., Xing, Chao, John, Esther M., Ambrosone, Christine B., Brancati, Frederick L., Coresh, Josef, Press, Michael F., Parekh, Rulan S., Klag, Michael J., Meoni, Lucy A., Hsueh, Wen-Chi, Fejerman, Laura, Pawlikowska, Ludmila, Freedman, Matthew L., Jandorf, Lina H., Bandera, Elisa V., Ciupak, Gregory L., Nalls, Michael A., Akylbekova, Ermeg L., Orwoll, Eric S., Leak, Tennille S., Miljkovic, Iva, Li, Rongling, Ursin, Giske, Bernstein, Leslie, Ardlie, Kristin, Taylor, Herman A., Boerwinckle, Eric, Zmuda, Joseph M., Henderson, Brian E., Wilson, James G., Reich, David“…The prevalence of obesity (body mass index (BMI) ≥30 kg/m(2)) is higher in African Americans than in European Americans, even after adjustment for socioeconomic factors, suggesting that genetic factors may explain some of the difference. …”
Publicado 2009
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6644por Lewis, Steven, Southern, Danielle A, Maxwell, Colleen J, Dunn, James R, Noseworthy, Tom W, Ghali, William A“…We sought to report the experiences and views of Americans living in Canada who have used both health care systems as adults. …”
Publicado 2007
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6645por Burgos, Paula I, Causey, Zenoria L, Tamhane, Ashutosh, Kelley, James M, Brown, Elizabeth E, Hughes, Laura B, Danila, Maria I, van Everdingen, Amalia, Conn, Doyt L, Jonas, Beth L, Callahan, Leigh F, Smith, Edwin A, Brasington, Richard D, Moreland, Larry W, van der Heijde, Désirée M, Alarcón, Graciela S, Bridges, S Louis“…INTRODUCTION: To determine whether IL4R single-nucleotide polymorphisms (SNPs) rs1805010 (I50V) and rs1801275 (Q551R), which have been associated with disease severity in rheumatoid arthritis (RA) patients of European ancestry, relate to the presence of rheumatoid nodules and radiographic erosions in African Americans. METHODS: Two IL4R SNPs, rs1805010 and rs1801275, were genotyped in 749 patients from the Consortium for Longitudinal Evaluation of African-Americans with Early Rheumatoid Arthritis (CLEAR) registries. …”
Publicado 2010
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6646por Chen, Gary K., Millikan, Robert C., John, Esther M., Ambrosone, Christine B., Bernstein, Leslie, Zheng, Wei, Hu, Jennifer J., Chanock, Stephen J., Ziegler, Regina G., Bandera, Elisa V., Henderson, Brian E., Haiman, Christopher A., Stram, Daniel O.“…Our results suggest that statistical correction for admixture differences is feasible for future studies of African-Americans, utilizing the existing controls from the African-American Breast Cancer study, even if case ascertainment for the future studies is not balanced over the same centers or regions that supplied the controls for the current study.…”
Publicado 2010
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6647por Nguyen, Tung T., Love, Mary Beth, Liang, Cindy, Fung, Lei-Chun, Nguyen, Thoa, Wong, Ching, Gildengorin, Ginny, Woo, Kent“…The research team recruited eight Chinese American (seven females, one male) lay health workers (LHWs). …”
Publicado 2010
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6648
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6649por Bidulescu, Aurelian, Din-Dzietham, Rebecca, Coverson, Dorothy L, Chen, Zhimin, Meng, Yuan-Xiang, Buxbaum, Sarah G, Gibbons, Gary H, Welch, Verna L“…BACKGROUND: Compared with whites, sleep disturbance and sleep deprivation appear more prevalent in African Americans (AA). Long-term sleep deprivation may increase the risk of obesity through multiple metabolic and endocrine alterations. …”
Publicado 2010
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6650“…We found that European Americans, unlike Chinese participants, did not show a “boss effect” and maintained the self-face advantage even in the presence of their supervisor's face. …”
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6651“…We examined health status and access to care among Asian Americans by the following acculturation indicators: nativity, percent lifetime in the US, self-rated English proficiency, and interview language, to assess whether any measure better distinguishes acculturation. …”
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6652por Wei, Gina S., Coady, Sean A., Goff, David C., Brancati, Frederick L., Levy, Daniel, Selvin, Elizabeth, Vasan, Ramachandran S., Fox, Caroline S.“…OBJECTIVE: We examined the association between high blood pressure and incident type 2 diabetes in African Americans and whites aged 35–54 years at baseline. …”
Publicado 2011
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6653por Khalili, Mandana, Guy, Jennifer, Yu, Albert, Li, Alexander, Diamond-Smith, Nadia, Stewart, Susan, Chen, Moon, Nguyen, Tung“…BACKGROUND: Physician patterns of screening for hepatitis B (HBV) and hepatocellular carcinoma (HCC) among Asian Americans are not well described. AIMS: To describe HBV and HCC screening practices among providers with large Asian American populations. …”
Publicado 2010
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6654por Wheeler, Heather E., Gorsic, Lidija K., Welsh, Marleen, Stark, Amy L., Gamazon, Eric R., Cox, Nancy J., Dolan, M. Eileen“…Although our results require further study, we have identified variants and genes associated with chemotherapeutic susceptibility in African Americans by using an approach that incorporates local ancestry information.…”
Publicado 2011
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6655por Kamran, Haroon, Lazar, Jason M., Patel, Rinkesh, Maraj, IIir, Berman, Heather, Salciccioli, Louis“…Mechanisms implicated for higher central pressures include a higher forward incident pressure wave (P1), higher augmented pressure (AP), and shorter reflected wave round trip travel time (Tr). African-Americans (AA) have more frequent and deleterious blood pressure elevation. …”
Publicado 2011
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6656por Fernandez, Senaida, Tobin, Jonathan N, Cassells, Andrea, Diaz-Gloster, Marleny, Kalida, Chamanara, Ogedegbe, Gbenga“…METHODS: Participants included 1,039 hypertensive African Americans receiving care in 30 CHCs in the New York Metropolitan area. …”
Publicado 2011
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6657“…PURPOSE: Findings from previous studies have not revealed significant, inverse relationships between socioeconomic position (SEP) and depression among African Americans. This study examined the relationship between multiple indicators of SEP and Major Depressive Episode (MDE) among African Americans. …”
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6658por Kidambi, Srividya, Ghosh, Soumitra, Kotchen, Jane M, Grim, Clarence E, Krishnaswami, Shanthi, Kaldunski, Mary L, Cowley, Allen W, Patel, Shailendra B, Kotchen, Theodore A“…BACKGROUND: A recent genome wide association study in 1017 African Americans identified several single nucleotide polymorphisms that reached genome-wide significance for systolic blood pressure. …”
Publicado 2012
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6659por O’Malley, A. James, Arbesman, Samuel, Steiger, Darby Miller, Fowler, James H., Christakis, Nicholas A.Enlace del recurso
Publicado 2012
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6660por Roewer, Lutz, Nothnagel, Michael, Gusmão, Leonor, Gomes, Veronica, González, Miguel, Corach, Daniel, Sala, Andrea, Alechine, Evguenia, Palha, Teresinha, Santos, Ney, Ribeiro-dos-Santos, Andrea, Geppert, Maria, Willuweit, Sascha, Nagy, Marion, Zweynert, Sarah, Baeta, Miriam, Núñez, Carolina, Martínez-Jarreta, Begoña, González-Andrade, Fabricio, Fagundes de Carvalho, Elizeu, da Silva, Dayse Aparecida, Builes, Juan José, Turbón, Daniel, Lopez Parra, Ana Maria, Arroyo-Pardo, Eduardo, Toscanini, Ulises, Borjas, Lisbeth, Barletta, Claudia, Ewart, Elizabeth, Santos, Sidney, Krawczak, Michael“…Numerous studies of human populations in Europe and Asia have revealed a concordance between their extant genetic structure and the prevailing regional pattern of geography and language. For native South Americans, however, such evidence has been lacking so far. …”
Publicado 2013
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