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6681por Blackburn, August, Almeida, Marcio, Dean, Angela, Curran, Joanne E, Johnson, Matthew P, Moses, Eric K, Abraham, Lawrence J, Carless, Melanie A, Dyer, Thomas D, Kumar, Satish, Almasy, Laura, Mahaney, Michael C, Comuzzie, Anthony, Williams-Blangero, Sarah, Blangero, John, Lehman, Donna M, Göring, Harald H H“…Here we identify effects of copy number variable regions (CNVRs) on nearby gene expression by investigating 909 CNVRs and expression levels of 12059 nearby genes in white blood cells from Mexican-American participants of the San Antonio Family Heart Study. …”
Publicado 2015
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6682por Jacovas, Vanessa Cristina, Rovaris, Diego Luiz, Peréz, Orlando, de Azevedo, Soledad, Macedo, Gabriel Souza, Sandoval, José Raul, Salazar-Granara, Alberto, Villena, Mercedes, Dugoujon, Jean-Michel, Bisso-Machado, Rafael, Petzl-Erler, Maria Luiza, Salzano, Francisco Mauro, Ashton-Prolla, Patricia, Ramallo, Virginia, Bortolini, Maria Cátira“…The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 individuals belonging to Quechua, Aymara, Chivay, Cabanaconde, Yanke, Taquile, Amantani, Anapia, Uros, Guarani Ñandeva, and Guarani Kaiowá populations, characterized as Native American or as having a high level (> 90%) of Native American ancestry. …”
Publicado 2015
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6683por Sakashita, Yu, Nakanishi, Shuhei, Yoneda, Masayasu, Nakashima, Reiko, Yamane, Kiminori, Kohno, Nobuoki“…MetS was defined on the basis of American Heart Association/National Heart, Lung, and Blood Institute criteria. …”
Publicado 2015
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6684“…CONCLUSIONS: Over- and underuse of medical care are important problems for many Americans, and experiences vary by race/ethnicity. …”
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6685por Del-Aguila, Jorge L., Fernández, Maria Victoria, Jimenez, Jessica, Black, Kathleen, Ma, Shengmei, Deming, Yuetiva, Carrell, David, Saef, Ben, Howells, Bill, Budde, John, Cruchaga, Carlos“…Here, we try to replicate the association between AD risk and ABCA7 loss-of-function variants at both the single-variant and gene level in a large and well-characterized European American dataset. METHODS: We genotyped the GWAS common variant and four rare variants previously reported for ABCA7 in 3476 European–Americans. …”
Publicado 2015
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6686por Sieverdes, John Christopher, Nemeth, Lynne S, Magwood, Gayenell S, Baliga, Prabhakar K, Chavin, Kenneth D, Brunner-Jackson, Brenda, Patel, Sachin K, Ruggiero, Kenneth J, Treiber, Frank A“…BACKGROUND: There is a critical need to expand the pool of available kidneys for African Americans who are on the transplant wait-list due to the disproportionally lower availability of deceased donor kidneys compared with other races/ethnic groups. …”
Publicado 2015
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6687por Hamadeh, IS, Shahin, MH, Lima, SM, Oliveira, F, Wilson, L, Khalifa, SI, Langaee, TY, Cooper‐DeHoff, RM, Cavallari, LH, Johnson, JA“…Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin dose requirements in African‐Americans. We sought to determine if they influenced warfarin dose in European‐Americans, and another African population, specifically Egyptians. …”
Publicado 2016
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6688por Sung, Jung Hye, Yeboah, Joseph, Lee, Jae Eun, Smith, Che L., Terry, James G., Sims, Mario, Samdarshi, Tandaw, Musani, Solomon, Fox, Ervin, Ge, Yaorong, Wilson, James G., Taylor, Herman A., Carr, J. Jeffery“…BACKGROUND: The role of coronary artery calcium (CAC) as a screening tool for cardiovascular disease (CVD) risk in African Americans (AAs) is unclear. We compared the diagnostic accuracy for CVD prevalence using the CAC score and the Framingham Risk Score (FRS) in an adult population of AAs. …”
Publicado 2015
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6689por Smalls, Brittany L., Walker, Rebekah J., Bonilha, Heather S., Campbell, Jennifer A., Egede, Leonard E.“…CONCLUSION: In general, the community interventions assessed led to significant reductions in HbA1C in African Americans with type 2 diabetes. Community health workers did not have a greater impact on glycemic control in this sample. …”
Publicado 2015
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6690por Basa, Ranor C. B., Davies, Vince, Li, Xiaoxiao, Murali, Bhavya, Shah, Jinel, Yang, Bing, Li, Shi, Khan, Mohammad W., Tian, Mengxi, Tejada, Ruth, Hassan, Avan, Washington, Allen, Mukherjee, Bhramar, Carethers, John M., McGuire, Kathleen L.“…Colorectal cancer is a leading cause of cancer related deaths in the U.S., with African-Americans having higher incidence and mortality rates than Caucasian-Americans. …”
Publicado 2016
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6691Age-period-cohort analysis of suicide mortality by gender among white and black Americans, 1983–2012por Wang, Zhenkun, Yu, Chuanhua, Wang, Jinyao, Bao, Junzhe, Gao, Xudong, Xiang, Huiyun“…BACKGROUND: Previous studies suggested that the racial differences in U.S. suicide rates are decreasing, particularly for African Americans, but the cause behind the temporal variations has yet to be determined. …”
Publicado 2016
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6692por Millen, Amy E., Sahli, Michelle W., Nie, Jing, LaMonte, Michael J., Lutsey, Pamela L., Klein, Barbara E. K., Mares, Julie A., Meyers, Kirstin J., Andrews, Christopher A., Klein, Ronald“…METHODS: Among participants in the Atherosclerosis Risk in Communities (ARIC) study with diabetes at visit 3 (1993–1995), 1339 (906 Caucasians, 433 African Americans) had serum 25-hydroxyvitamin (25[OH]D) concentrations assessed at visit 2 (1989–1992) and nonmydriatic retinal photographs taken at visit 3. …”
Publicado 2016
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6693“…Objective: To examine the individual and combined effects of depression and diabetes on mortality and disability over 6 years among Mexican Americans aged ≥75. Method: The final sample included 1,785 participants from the Hispanic Established Population for the Epidemiological Study of the Elderly. …”
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6694por Franceschini, Nora, Carty, Cara L., Lu, Yingchang, Tao, Ran, Sung, Yun Ju, Manichaikul, Ani, Haessler, Jeff, Fornage, Myriam, Schwander, Karen, Zubair, Niha, Bien, Stephanie, Hindorff, Lucia A., Guo, Xiuqing, Bielinski, Suzette J., Ehret, Georg, Kaufman, Joel D., Rich, Stephen S., Carlson, Christopher S., Bottinger, Erwin P., North, Kari E., Rao, D. C., Chakravarti, Aravinda, Barrett, Paula Q., Loos, Ruth J. F., Buyske, Steven, Kooperberg, Charles“…Using the Metabochip array, we sought to characterize the genetic architecture of previously identified blood pressure loci, and identify novel cardiometabolic variants related to systolic and diastolic blood pressure in a multi-ethnic US population including Hispanics (n = 19,706) and African Americans (n = 18,744). Several known blood pressure loci replicated in African Americans and Hispanics. …”
Publicado 2016
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6695por Pescatello, Linda S., Schifano, Elizabeth D., Ash, Garrett I., Panza, Gregory A., Lamberti, Lauren, Chen, Ming‐Hui, Deshpande, Ved, Zaleski, Amanda, Farinatti, Paulo, Taylor, Beth A., Thompson, Paul D.“…Obese (30.9 ± 3.6 kg m(−2)) adults (n = 23; 61% African Americans [AF], 39% Caucasian) 42.0 ± 9.8 years with hypertension (139.8 ± 10.4/84.6 ± 6.2 mmHg) completed three random experiments: bouts of vigorous and moderate intensity cycling and control. …”
Publicado 2016
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6696por Quinlan, Jacklyn, Pearson, Laurel N., Clukay, Christopher J., Mitchell, Miaisha M., Boston, Qasimah, Gravlee, Clarence C., Mulligan, Connie J.“…Hypertension is a leading risk factor for cardiovascular disease and afflicts more African Americans than any other racially defined group in the US. …”
Publicado 2016
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6697por Schneider, Bryan P., Lai, Dongbing, Shen, Fei, Jiang, Guanglong, Radovich, Milan, Li, Lang, Gardner, Laura, Miller, Kathy D., O'Neill, Anne, Sparano, Joseph A., Xue, Gloria, Foroud, Tatiana, Sledge, George W.“…PURPOSE: Taxane-induced peripheral neuropathy (TIPN) is one of the most important survivorship issues for cancer patients. African Americans (AA) have previously been shown to have an increased risk for this toxicity. …”
Publicado 2016
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6698por Collins, Tracie C., Slovut, David P., Newton, Robert, Johnson, William D., Larrivee, Sandra, Patterson, Jeremy, Johnston, Judy A., Correa, Adolfo“…African American men and women (N = 4403) age 35–84 years participated in the study. …”
Publicado 2017
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6699por Shendre, Aditi, Irvin, Marguerite R., Wiener, Howard, Zhi, Degui, Limdi, Nita A., Overton, Edgar T., Shrestha, Sadeep“…BACKGROUND: Local ancestry in relation to clinical cardiovascular events (CVEs) among African Americans can provide insight into their genetic susceptibility to the disease. …”
Publicado 2017
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6700por Riestra, Pia, Gebreab, Samson Y, Xu, Ruihua, Khan, Rumana J, Quarels, Rakale, Gibbons, Gary, Davis, Sharon K“…The purpose of this study was to explore the associations between the risk of obstructive sleep apnea and telomere length in African Americans. METHODS: The analysis included 184 women and 122 men aged 30–55 years from the Morehouse School of Medicine Study. …”
Publicado 2017
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