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6701por Chandler, Madison R., Keene, Kimberly S., Tuomela, Johanna M., Forero-Torres, Andres, Desmond, Renee, Vuopala, Katri S., Harris, Kevin W., Merner, Nancy D., Selander, Katri S.“…Germline TLR9 variants in European Americans (EAs) and AAs were investigated, to determine their contribution to AA breast cancer risk. …”
Publicado 2017
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6702por Chan, Gary C., Divers, Jasmin, Russell, Gregory B., Langefeld, Carl D., Wagenknecht, Lynne E., Xu, Jianzhao, Smith, S. Carrie, Bowden, Donald W., Register, Thomas C., Carr, J. Jeffrey, Lenchik, Leon, Freedman, Barry I.“…This study was performed to assess cross-sectional and longitudinal relationships between computed tomography-determined visceral (VAT), subcutaneous (SAT), inter-muscular (IMAT), and pericardial adipose tissue (PAT) volumes with respective changes in thoracic vertebral and lumbar vertebral volumetric trabecular bone mineral density (vBMD) in African Americans with type 2 diabetes. Generalized linear models were fitted to test relationships between baseline and change in adipose volumes with change in vBMD in 300 African American-Diabetes Heart Study participants; adjustment was performed for age, sex, diabetes duration, study interval, smoking, hypertension, BMI, kidney function, and medications. …”
Publicado 2018
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6703
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6704por Assari, Shervin“…Methods: With a cross-sectional design, the National Survey of American Life (NSAL), 2003, included 3570 non-Hispanic African Americans and 891 non-Hispanic Whites. …”
Publicado 2018
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6705por Charles, Bashira A., Hsieh, Matthew M., Adeyemo, Adebowale A., Shriner, Daniel, Ramos, Edward, Chin, Kyung, Srivastava, Kshitij, Zakai, Neil A., Cushman, Mary, McClure, Leslie A., Howard, Virginia, Flegel, Willy A., Rotimi, Charles N., Rodgers, Griffin P.“…METHODS: We conducted an extreme phenotype design genome-wide association study (GWAS), analyzed ~16 million single nucleotide polymorphisms (SNP) in 1,178 African-Americans individuals from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study and replicated from 819 African-American participants in the Atherosclerosis Risk in Communities (ARIC) study. …”
Publicado 2018
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6706por Murray, Michael D., Hendrie, Hugh C., Lane, Kathleen A., Zheng, Mengjie, Ambuehl, Roberta, Li, Shanshan, Unverzagt, Frederick W., Callahan, Christopher M., Gao, Sujuan“…BACKGROUND: African Americans are especially at risk of hypertension and dementia. …”
Publicado 2018
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6707por Tabet, Maya, Sanders, Erin A., Schootman, Mario, Chang, Jen Jen, Wolinsky, Fredric D., Malmstrom, Theodore K., Miller, Douglas K.“…Objective: We examined associations between observed neighborhood conditions (good/adverse) and psychosocial outcomes (stress, depressive symptoms, resilience, and sense of control) among middle-aged and older African Americans. Methods: The sample included 455 middle-aged and older African Americans examined in Wave 10 of the African American Health (AAH) study. …”
Publicado 2016
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6708por Kim, Eun Ji, Kressin, Nancy R., Paasche-Orlow, Michael K., Lopez, Lenny, Rosen, Jennifer E., Lin, Mengyun, Hanchate, Amresh D.“…But little is known about this outcome among Asian Americans (Asians), a fast growing racial/ethnic minority in the country. …”
Publicado 2018
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6709por Cologne, John, Loo, Lenora, Shvetsov, Yurii B., Misumi, Munechika, Lin, Philip, Haiman, Christopher A., Wilkens, Lynne R., Le Marchand, LoïcEnlace del recurso
Publicado 2018
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6711“…BACKGROUND: Compared with other racial and ethnic groups, African Americans are disproportionately burdened by high rates of deaths due to diabetes. …”
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6712por Lynn, Heather, Sun, Xiaoguang, Ayshiev, Djanybek, Siegler, Jessica H., Rizzo, Alicia N., Karnes, Jason H., Gonzales Garay, Manuel, Wang, Ting, Casanova, Nancy, Camp, Sara M., Ellis, Nathan A., Garcia, Joe GN“…Genotyping studies identified two MYLKP1 SNPs (rs12490683; rs12497343) that significantly increase risk of colon cancer in African Americans compared to African American controls. Rs12490683 and rs12497343 further increase MYLKP1 promoter activity compared to the wild type MYLKP1 promoter. …”
Publicado 2018
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6713“…Objective: Food insecurity remains a major public health issue in the United States, though lack of research among Asian Americans continue to underreport the issue. The purpose of this study was to evaluate the prevalence and burden of food insecurity among disaggregated Asian American populations. …”
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6714por Conway, Olivia J, Carrasquillo, Minerva M, Wang, Xue, Bredenberg, Jenny M, Reddy, Joseph S, Strickland, Samantha L, Younkin, Curtis S, Burgess, Jeremy D, Allen, Mariet, Lincoln, Sarah J, Nguyen, Thuy, Malphrus, Kimberly G, Soto, Alexandra I, Walton, Ronald L, Boeve, Bradley F, Petersen, Ronald C, Lucas, John A, Ferman, Tanis J, Cheshire, William P, van Gerpen, Jay A, Uitti, Ryan J, Wszolek, Zbigniew K, Ross, Owen A, Dickson, Dennis W, Graff-Radford, Neill R, Ertekin-Taner, Nilüfer“…METHODS: We tested the association of these variants with five neurodegenerative diseases in Caucasian case-control cohorts: 2742 AD, 231 progressive supranuclear palsy (PSP), 838 Parkinson’s disease (PD), 306 dementia with Lewy bodies (DLB) and 150 multiple system atrophy (MSA) vs. 3351 controls; and in an African-American AD case-control cohort (181 AD, 331 controls). 1479 AD and 1491 controls were non-overlapping with a prior report. …”
Publicado 2018
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6715por Han, Seung Jin, Boyko, Edward J., Kim, Soo-Kyung, Fujimoto, Wilfred Y., Kahn, Steven E., Leonetti, Donna L.“…Greater thigh muscle area predicts a lower risk of incident T2DM for leaner Japanese Americans.…”
Publicado 2018
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6716por Chacón-Duque, Juan-Camilo, Adhikari, Kaustubh, Fuentes-Guajardo, Macarena, Mendoza-Revilla, Javier, Acuña-Alonzo, Victor, Barquera, Rodrigo, Quinto-Sánchez, Mirsha, Gómez-Valdés, Jorge, Everardo Martínez, Paola, Villamil-Ramírez, Hugo, Hünemeier, Tábita, Ramallo, Virginia, Silva de Cerqueira, Caio C., Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Villena, Mercedes, Vásquez, René, Llop, Elena, Sandoval, José R., Salazar-Granara, Alberto A., Parolin, Maria-Laura, Sandoval, Karla, Peñaloza-Espinosa, Rosenda I., Rangel-Villalobos, Hector, Winkler, Cheryl A., Klitz, William, Bravi, Claudio, Molina, Julio, Corach, Daniel, Barrantes, Ramiro, Gomes, Verónica, Resende, Carlos, Gusmão, Leonor, Amorim, Antonio, Xue, Yali, Dugoujon, Jean-Michel, Moral, Pedro, González-José, Rolando, Schuler-Faccini, Lavinia, Salzano, Francisco M., Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Poletti, Giovanni, Gallo, Carla, Bedoya, Gabriel, Rothhammer, Francisco, Balding, David, Hellenthal, Garrett, Ruiz-Linares, Andrés“…Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. …”
Publicado 2018
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6717por Zhao, Xueyan, Geng, Xin, Srinivasasainagendra, Vinodh, Chaudhary, Ninad, Judd, Suzanne, Wadley, Virginia, Gutiérrez, Orlando M., Wang, Henry, Lange, Ethan M., Lange, Leslie A., Woo, Daniel, Unverzagt, Frederick W., Safford, Monika, Cushman, Mary, Limdi, Nita, Quarells, Rakale, Arnett, Donna K., Irvin, Marguerite R., Zhi, Degui“…However, knowledge of genetic determinants of those diseases in African Americans remains limited. RESULTS: In our study, associations between 4956 GWAS catalog reported SNPs and 67 traits were examined among 7726 African Americans from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, which is focused on identifying factors that increase stroke risk. …”
Publicado 2019
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6718por Silzer, Talisa, Barber, Robert, Sun, Jie, Pathak, Gita, Johnson, Leigh, O’Bryant, Sid, Phillips, Nicole“…Studying the shared phenomena in Mexican Americans is of particular importance due to the disproportionate prevalence of both T2D and AD in this population. …”
Publicado 2019
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6719por Spear, Melissa L., Hu, Donglei, Pino-Yanes, Maria, Huntsman, Scott, Eng, Celeste, Levin, Albert M., Ortega, Victor E., White, Marquitta J., McGarry, Meghan E., Thakur, Neeta, Galanter, Joshua, Mak, Angel C.Y., Oh, Sam S., Ampleford, Elizabeth, Peters, Stephen P., Davis, Adam, Kumar, Rajesh, Farber, Harold J., Meade, Kelley, Avila, Pedro C., Serebrisky, Denise, Lenoir, Michael A., Brigino-Buenaventura, Emerita, Cintron, William Rodriguez, Thyne, Shannon M., Rodriguez-Santana, Jose R., Ford, Jean G., Chapela, Rocio, Estrada, Andrés Moreno, Sandoval, Karla, Seibold, Max A., Winkler, Cheryl A., Bleecker, Eugene R., Myers, Deborah A., Keoki Williams, L., Hernandez, Ryan D., Torgerson, Dara G., Burchard, Esteban G.“…However, the genetic variation that contributes to BDR is largely undefined in African Americans with asthma(3). To identify genetic variants that may contribute to differences in BDR in African Americans with asthma, we performed a genome-wide association study (GWAS) of BDR in 949 African American children with asthma, genotyped with the Axiom World Array 4 (Affymetrix, Santa Clara, CA) followed by imputation using 1000 Genomes phase III genotypes. …”
Publicado 2018
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6720“…While ABCA7 rs115550680 has been linked to the development of late-onset AD in African Americans, no association between ABCA7 variant rs3764650 and AD has been found in this population. …”
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