Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

por Hu, Shikai, Liu, Silvia, Bian, Yu, Poddar, Minakshi, Singh, Sucha, Cao, Catherine, McGaughey, Jackson, Bell, Aaron, Blazer, Levi L., Adams, Jarret J., Sidhu, Sachdev S., Angers, Stephane, Monga, Satdarshan P.
Publicado 2022

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

por Tao, Yuyong, Mis, Monika, Blazer, Levi, Ustav, Mart, Steinhart, Zachary, Chidiac, Rony, Kubarakos, Elli, O'Brien, Siobhan, Wang, Xiaomei, Jarvik, Nick, Patel, Nish, Adams, Jarrett, Moffat, Jason, Angers, Stephane, Sidhu, Sachdev S
Publicado 2019

Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates

por Falcon, Benjamin, Cavallini, Annalisa, Angers, Rachel, Glover, Sarah, Murray, Tracey K., Barnham, Luanda, Jackson, Samuel, O'Neill, Michael J., Isaacs, Adrian M., Hutton, Michael L., Szekeres, Philip G., Goedert, Michel, Bose, Suchira
Publicado 2015

Molecular characterization of an unauthorized genetically modified Bacillus subtilis production strain identified in a vitamin B(2) feed additive

por Paracchini, Valentina, Petrillo, Mauro, Reiting, Ralf, Angers-Loustau, Alexandre, Wahler, Daniela, Stolz, Andrea, Schönig, Birgit, Matthies, Anastasia, Bendiek, Joachim, Meinel, Dominik M., Pecoraro, Sven, Busch, Ulrich, Patak, Alex, Kreysa, Joachim, Grohmann, Lutz
Publicado 2017

CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma

por Houles, Thibault, Lavoie, Geneviève, Nourreddine, Sami, Cheung, Winnie, Vaillancourt-Jean, Éric, Guérin, Célia M., Bouttier, Mathieu, Grondin, Benoit, Lin, Sichun, Saba-El-Leil, Marc K., Angers, Stephane, Meloche, Sylvain, Roux, Philippe P.
Publicado 2022

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

por Chidiac, Rony, Abedin, Md., Macleod, Graham, Yang, Andy, Thibeault, Pierre E, Blazer, Levi L, Adams, Jarrett J, Zhang, Lingling, Roehrich, Heidi, Jo, Ha‐Neul, Seshagiri, Somasekar, Sidhu, Sachdev S, Junge, Harald J, Angers, Stephane
Publicado 2021

A Bacterial Acetyltransferase Destroys Plant Microtubule Networks and Blocks Secretion

por Lee, Amy Huei-Yi, Hurley, Brenden, Felsensteiner, Corinna, Yea, Carmen, Ckurshumova, Wenzislava, Bartetzko, Verena, Wang, Pauline W., Quach, Van, Lewis, Jennifer D., Liu, Yulu C., Börnke, Frederik, Angers, Stephane, Wilde, Andrew, Guttman, David S., Desveaux, Darrell
Publicado 2012

Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling

por Kejiou, Nevraj S, Ilan, Lena, Aigner, Stefan, Luo, Enching, Tonn, Tori, Ozadam, Hakan, Lee, Muyoung, Cole, Gregory B, Rabano, Ines, Rajakulendran, Nishani, Yee, Brian A, Najafabadi, Hamed S, Moraes, Trevor F, Angers, Stephane, Yeo, Gene W, Cenik, Can, Palazzo, Alexander F
Publicado 2023

Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes

por Wang, Xian, Gong, Zheyuan, Wang, Tiancong, Law, Junhui, Chen, Xin, Wanggou, Siyi, Wang, Jintian, Ying, Binbin, Francisco, Michelle, Dong, Weifan, Xiong, Yi, Fan, Jerry J., MacLeod, Graham, Angers, Stephane, Li, Xuejun, Dirks, Peter B., Liu, Xinyu, Huang, Xi, Sun, Yu
Publicado 2023

Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition

por Cao, Wen Xi, Kabelitz, Sarah, Gupta, Meera, Yeung, Eyan, Lin, Sichun, Rammelt, Christiane, Ihling, Christian, Pekovic, Filip, Low, Timothy C.H., Siddiqui, Najeeb U., Cheng, Matthew H.K., Angers, Stephane, Smibert, Craig A., Wühr, Martin, Wahle, Elmar, Lipshitz, Howard D.
Publicado 2020

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

por Aubert, Léo, Nandagopal, Neethi, Steinhart, Zachary, Lavoie, Geneviève, Nourreddine, Sami, Berman, Jacob, Saba-El-Leil, Marc K., Papadopoli, David, Lin, Sichun, Hart, Traver, Macleod, Graham, Topisirovic, Ivan, Gaboury, Louis, Fahrni, Christoph J., Schramek, Daniel, Meloche, Sylvain, Angers, Stephane, Roux, Philippe P.
Publicado 2020

The Human PDZome: A Gateway to PSD95-Disc Large-Zonula Occludens (PDZ)-mediated Functions

por Belotti, Edwige, Polanowska, Jolanta, Daulat, Avais M., Audebert, Stéphane, Thomé, Virginie, Lissitzky, Jean-Claude, Lembo, Frédérique, Blibek, Karim, Omi, Shizue, Lenfant, Nicolas, Gangar, Akanksha, Montcouquiol, Mireille, Santoni, Marie-Josée, Sebbagh, Michael, Aurrand-Lions, Michel, Angers, Stéphane, Kodjabachian, Laurent, Reboul, Jérome, Borg, Jean-Paul
Publicado 2013

Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates

por Saleeb, Rebecca S., Leighton, Craig, Lee, Ji-Eun, O’Shaughnessy, Judi, Jeacock, Kiani, Chappard, Alexandre, Cumberland, Robyn, Zhao, Tianxiao, Ball, Sarah R., Sunde, Margaret, Clarke, David J., Piché, Kristin, McPhail, Jacob A., Louwrier, Ariel, Angers, Rachel, Gandhi, Sonia, Downey, Patrick, Kunath, Tilo, Horrocks, Mathew H.
Publicado 2023

How to measure, report and verify soil carbon change to realize the potential of soil carbon sequestration for atmospheric greenhouse gas removal

por Smith, Pete, Soussana, Jean‐Francois, Angers, Denis, Schipper, Louis, Chenu, Claire, Rasse, Daniel P., Batjes, Niels H., van Egmond, Fenny, McNeill, Stephen, Kuhnert, Matthias, Arias‐Navarro, Cristina, Olesen, Jorgen E., Chirinda, Ngonidzashe, Fornara, Dario, Wollenberg, Eva, Álvaro‐Fuentes, Jorge, Sanz‐Cobena, Alberto, Klumpp, Katja
Publicado 2019

The EU one-stop-shop collection of publicly available information on COVID-19 in vitro diagnostic medical devices

por Petrillo, Mauro, Querci, Maddalena, Tkachenko, Olga, Siska, Ioana-Raluca, Ben, Enrico, Angers-Loustau, Alexandre, Bogni, Alessia, Brunetto, Antonino, Fabbri, Marco, Garlant, Linda, Lievens, Antoon, Munoz, Amalia, Paracchini, Valentina, Pietretti, Danilo, Puertas-Gallardo, Antonio, Raffael, Barbara, Sarno, Eleonora, Tregoat, Virginie, Zaro, Fabrizio, Van den Eede, Guy
Publicado 2020

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau

por Courade, Jean-Philippe, Angers, Rachel, Mairet-Coello, Georges, Pacico, Nathalie, Tyson, Kerry, Lightwood, Daniel, Munro, Rebecca, McMillan, David, Griffin, Robert, Baker, Terry, Starkie, Dale, Nan, Ruodan, Westwood, Marta, Mushikiwabo, Marie-Laetitia, Jung, Sophie, Odede, Geofrey, Sweeney, Berni, Popplewell, Andrew, Burgess, Gillian, Downey, Patrick, Citron, Martin
Publicado 2018

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

por Rajakulendran, Nishani, Rowland, Katherine J., Selvadurai, Hayden J., Ahmadi, Moloud, Park, Nicole I., Naumenko, Sergey, Dolma, Sonam, Ward, Ryan J., So, Milly, Lee, Lilian, MacLeod, Graham, Pasiliao, Clarissa, Brandon, Caroline, Clarke, Ian D., Cusimano, Michael D., Bernstein, Mark, Batada, Nizar, Angers, Stephane, Dirks, Peter B.
Publicado 2019

ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development

por Magomedova, Lilia, Tiefenbach, Jens, Zilberman, Emma, Le Billan, Florian, Voisin, Veronique, Saikali, Michael, Boivin, Vincent, Robitaille, Melanie, Gueroussov, Serge, Irimia, Manuel, Ray, Debashish, Patel, Rucha, Xu, ChangJiang, Jeyasuria, Pancharatnam, Bader, Gary D, Hughes, Timothy R, Morris, Quaid D, Scott, Michelle S, Krause, Henry, Angers, Stephane, Blencowe, Benjamin J, Cummins, Carolyn L
Publicado 2019

The challenges of designing a benchmark strategy for bioinformatics pipelines in the identification of antimicrobial resistance determinants using next generation sequencing techno...

por Angers-Loustau, Alexandre, Petrillo, Mauro, Bengtsson-Palme, Johan, Berendonk, Thomas, Blais, Burton, Chan, Kok-Gan, Coque, Teresa M., Hammer, Paul, Heß, Stefanie, Kagkli, Dafni M., Krumbiegel, Carsten, Lanza, Val F., Madec, Jean-Yves, Naas, Thierry, O'Grady, Justin, Paracchini, Valentina, Rossen, John W.A., Ruppé, Etienne, Vamathevan, Jessica, Venturi, Vittorio, Van den Eede, Guy
Publicado 2018

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

por Zimmermann, Michal, Murina, Olga, Reijns, Martin A. M., Agathanggelou, Angelo, Challis, Rachel, Tarnauskaitė, Žygimantė, Muir, Morwenna, Fluteau, Adeline, Aregger, Michael, McEwan, Andrea, Yuan, Wei, Clarke, Matthew, Lambros, Maryou B., Paneesha, Shankara, Moss, Paul, Chandrashekhar, Megha, Angers, Stephane, Moffat, Jason, Brunton, Valerie G., Hart, Traver, de Bono, Johann, Stankovic, Tatjana, Jackson, Andrew P., Durocher, Daniel
Publicado 2018