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2401“…In this respect, marine animals have been used to extract many new compounds exerting different actions. …”
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2402“…Through this interaction a cascade of events responsible for the MC cytotoxic and genotoxic effects in animal cells may take place. Moreover MC induces oxidative stress in animal cells and together with the inhibition of PPs, this pathway is considered to be one of the main mechanisms of MC toxicity. …”
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2403“…The 3-D skin equivalent can be viewed as physiologically comparable to the natural skin and therefore is a suitable alternative for animal testing. This highly differentiated in vitro human skin equivalent is used to assess the efficacy and mode of action of novel agents. …”
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2404“…The extension of the model to non-genotyped animals is made by using the pedigree to derive an extension of the genomic relationship matrix to non-genotyped animals. …”
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2405
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2406“…Hence, emphasis is given on animal trade and suitable ecologic conditions, including competent vectors and vertebrate hosts.…”
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2407
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2408por Emmanuel, Francis Xavier, Seagar, Amie-Louise, Doig, Christine, Rayner, Alan, Claxton, Pauline, Laurenson, Ian“…During 1994–2005, we isolated Mycobacterium microti from 5 animals and 4 humans. Only 1 person was immunocompromised. …”
Publicado 2007
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2409
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2410
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2411por Workman, P, Aboagye, E O, Balkwill, F, Balmain, A, Bruder, G, Chaplin, D J, Double, J A, Everitt, J, Farningham, D A H, Glennie, M J, Kelland, L R, Robinson, V, Stratford, I J, Tozer, G M, Watson, S, Wedge, S R, Eccles, S A“…Excellent standards of animal care are fully consistent with the conduct of high quality cancer research. …”
Publicado 2010
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2412“…In periodontal research, animal studies are complementary to in vitro experiments prior to testing new treatments. …”
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2413“…However, the relative contributions of the different molecular mechanisms that underlie domain gains in animals are still unknown. By using animal gene phylogenies we were able to identify a set of high confidence domain gain events and by looking at their coding DNA investigate the causative mechanisms. …”
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2414
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2415“…We have reviewed the different animal models and biomarkers of neuropathy in diabetic rodents of either type 1 or type 2 diabetes.…”
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2416
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2417“…Animals can be used in many ways in science and scientific research. …”
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2418por Bhattarai, Narayan Raj, Van der Auwera, Gert, Rijal, Suman, Picado, Albert, Speybroeck, Niko, Khanal, Basudha, De Doncker, Simonne, Das, Murari Lal, Ostyn, Bart, Davies, Clive, Coosemans, Marc, Berkvens, Dirk, Boelaert, Marleen, Dujardin, Jean-Claude“…To determine possible reasons for its persistence during interepidemic periods, we mapped Leishmania infections among healthy persons and animals in an area of active VL transmission in Nepal. …”
Publicado 2010
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2419por Delles, Christian, McBride, Martin W., Graham, Delyth, Padmanabhan, Sandosh, Dominiczak, Anna F.“…It has therefore been difficult to discover the genes that contribute to blood pressure variation using traditional approaches including candidate gene studies and linkage studies. Animal models of hypertension, particularly in the rat, have led to the discovery of quantitative trait loci harbouring one or several hypertension related genes, but translation of these findings into human essential hypertension remains challenging. …”
Publicado 2010
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2420